Wholesale Price China Sodium Valproate - Palbociclib CAS 571190-30-2 Purity >99.5% (HPLC) API Factory – Ruifu

Ruifu Chemical Supply Palbociclib Related Intermediates:
Palbociclib CAS 571190-30-2
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Package: Bottle, Aluminium foil bag, 25kg/Cardboard Drum, or according to customer’s requirement

Storage Condition: Store in sealed containers at cool and dry place; Protect from light and moisture

Palbociclib (CAS: 571190-30-2) is an orally available cyclin-dependent kinase (CDK) inhibitor with potential antineoplastic activity. Palbociclib selectively inhibits cyclin-dependent kinase 4 (CDK4) and 6 (CDK6), thereby inhibiting retinoblastoma (Rb) protein phosphorylation early in the G1 phase leading to cell cycle arrest. This suppresses DNA replication and decreases tumor cell proliferation. Palbociclib is the first representative of the new drug class of cyclin-dependent kinase inhibitors. This effect limits cell proliferation (cell growth and division). It is used as an antineoplastic agent in advanced or metastatic breast cancer.