1-(4-Aminophenyl) -4-(4-hydroxyphenyl)piperazine CAS 74853-08-0 Posaconazole Intermediate Purity ≥99.0%
IFactory Supply Posaconazole Related Intermediates, Commercial Production
I-Posaconazole CAS 171228-49-2
I-Posaconazole ePhakathi POA CAS 149809-43-8
Phenyl (4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)carbamate CAS 184177-81-9
1-(4-Aminophenyl)-4-(4-hydroxyphenyl)piperazine CAS 74853-08-0
2-[(1S,2S)-1-Ethyl-2-(phenylmethoxy)propyl]hydrazinecarboxal CAS 170985-85-0
I-Diethyl L-(+)-Tartrate CAS 87-91-2
Igama leMchiza | 1-(4-Aminophenyl)-4-(4-hydroxyphenyl)piperazine |
Izithethantonye | 4-[4-(4-Aminophenyl)piperazin-1-yl]phenol |
Inombolo yeCAS | 74853-08-0 |
Inombolo yeCAT | RF-PI292 |
Ubume beStokhwe | Kwi-Stock, iMveliso yoMveliso ukuya kwiiToni |
Ifomula yeemolekyuli | I-C16H19N3O |
Ubunzima beMolekyuli | 269.34 |
Indawo yokunyibilika | >180℃(ngoDisemba) |
Ukuxinana | 1.237g/cm3 |
Imeko yokuthumela ngenqanawa | Phantsi koBubushushu be-Ambient |
Uphawu | Ruifu Chemical |
Into | Iinkcukacha |
Imbonakalo | Umdaka omdaka ukuya kwiPowder emhlophe |
Ubunyulu | ≥99.0% |
Ilahleko ekomisweni | ≤0.50% |
Intsalela kwi-Ignition | ≤0.20% |
Ukungacoceki Okukodwa | ≤0.50% |
Ukungcola ngokupheleleyo | ≤1.0% |
Iintsimbi ezinzima (njenge Pb) | ≤20ppm |
Izinyibilikisi ezishiyekileyo | Hlangana nemigaqo |
Umgangatho woVavanyo | Umgangatho woShishino |
Ukusetyenziswa | Umbindi wePosaconazole (CAS 171228-49-2) |
Iphakheji: Ibhotile, ingxowa yefoyile yeAluminiyam, igubu lekhadibhodi, 25kg/Igubu, okanye ngokwemfuno yomthengi.
Imeko yoGcino:Gcina kwizikhongozeli ezivaliweyo kwindawo epholileyo neyomileyo;Khusela ekukhanyeni, ukufuma kunye nokuhlaselwa zizinambuzane.
I-1- (4-Aminophenyl) -4- (4-hydroxyphenyl) ipiperazine (CAS 74853-08-0) iphakathi kwePosaconazole (CAS 171228-49-2).I-Posaconazole lichiza le-triazole le-antifungal elithengiswa e-United States ngu-Schering-Plough phantsi kwegama lezorhwebo elithi Noxafil.I-Posaconazole i-spectrum ebanzi, isizukulwana sesibini, i-triazole edibeneyo kunye nomsebenzi we-antifungal.I-Posaconazole inqanda kakhulu i-14-alpha demethylase, i-cytochrome P450-exhomekeke kwi-enzyme.Ukuvinjelwa kwe-14-alpha-demethylase kuthintela ukuguqulwa kwe-lanosterol kwi-ergosterol, inxalenye ebalulekileyo yodonga lwe-fungal cell.Xa kuthelekiswa nezinye i-azole antifungals, i-posaconazole iyi-inhibitor enamandla kakhulu ye-sterol 14-alpha demethylase.