1-[(4-Nitrophenylmethyl)sulfonyl]pyrrolidine CAS 340041-91-0 Ubunyulu>98.0% (HPLC) Almotriptan Malate Intermediate Factory
I-Ruifu Chemical Supply Almotriptan Malate Intermediates:
Almotriptan Malate CAS 181183-52-8
I-1-((4-Hydrazinylbenzyl)sulfonyl)pyrrolidine Hydrochloride CAS 334981-11-2
4-[(1-Pyrrolidinylsulfonyl)methyl]aniline CAS 334981-10-1
1-[(4-Nitrophenylmethyl)sulfonyl]pyrrolidine CAS 340041-91-0
I-4-Chlorobutyraldehyde Diethyl Acetal CAS 6139-83-9
Igama leMchiza | 1-[(4-Nitrophenylmethyl)sulfonyl]pyrrolidine |
Izithethantonye | N-[(4-Nitrophenyl)-methylsulfonyl]pyryolidine;I-1-((4-Nitrobenzyl)sulfonyl)pyrrolidine |
Inombolo yeCAS | 340041-91-0 |
Inombolo yeCAT | RF-PI1959 |
Ubume beStokhwe | Kwi-Stock, iMveliso yoMveliso ukuya kwiiToni |
Ifomula yeemolekyuli | I-C11H14N2O4S |
Ubunzima beMolekyuli | 270.30 |
Uphawu | Ruifu Chemical |
Into | Iinkcukacha |
Ubunyulu / Indlela yokuHlalutya | >98.0% (HPLC) |
Ilahleko ekomisweni | <1.00% |
Umgangatho woVavanyo | Umgangatho woShishino |
Ukusetyenziswa | Umbindi we-Almotriptan Malate (CAS: 181183-52-8) |
Iphakheji: Ibhotile, ingxowa yefoyile yeAluminiyam, 25kg/Igubu lekhadibhodi, okanye ngokwemfuno yomthengi
Imeko yoGcino:Gcina kwizikhongozeli ezivaliweyo kwindawo epholileyo neyomileyo;Khusela ukukhanya kunye nokufuma
I-1-[(4-Nitrophenylmethyl)sulfonyl]pyrrolidine (CAS: 340041-91-0) yindawo ephakathi kuLungiselelo lwe-Almotriptan Malate (CAS: 181183-52-8).I-Almotriptan Malate yi-agonist ye-serotonin (5-HT) i-receptor subtypes ye-5-HT1Bkunye ne-5-HT1D(NDIYABONA50s=12 kunye ne-13 nM, ngokulandelelanayo, kwi-radioligand binding assay).I-Almotriptan Malate (i-LAS 31416) i-5-hydroxytryptamine1B / 1D (5-HT1B / 1D) i-receptor agonist ekhethiweyo, esetyenziselwa unyango lwe-Migraine ukuhlaselwa kwabantu abadala.I-Almotriptan, ithengiswe ngo-2000, ineyona ndawo iphezulu ye-oralbioavailability kuzo zonke iitriptan.I-metabolized yi-MAO-A kunye ne-CYP3A4, ngoko ke ineprofayili yeziphumo ezithandekayo xa ithelekiswa ne-Sumatriptan.