I-1-Chlorocarbonyl-4-Piperidinopiperidine Hydrochloride CAS 143254-82-4 Irinotecan Hydrochloride ePhakathi Ucoceko oluPhezulu
Ubonelelo lwabavelisi be-Irinotecan kunye nabaPhakathi abaNxulumeneyo:
Irinotecan Hydrochloride CAS: 100286-90-6
I-Irinotecan Isiseko sasimahla seCAS: 97682-44-5
Irinotecan Hydrochloride Trihydrate CAS: 136572-09-3
I-7-Ethyl-10-Hydroxycamptothecin CAS: 86639-52-3
I-1-Chlorocarbonyl-4-Piperidinopiperidine Hydrochloride CAS: 143254-82-4
| Igama leMchiza | I-1-Chlorocarbonyl-4-Piperidinopiperidine Hydrochloride |
| Inombolo yeCAS | 143254-82-4 |
| Inombolo yeCAT | RF-PI243 |
| Ubume beStokhwe | Kwi-Stock, iMveliso yoMveliso ukuya kwiiToni |
| Ifomula yeemolekyuli | I-C11H20Cl2N2O |
| Ubunzima beMolekyuli | 267.2 |
| Uphawu | Ruifu Chemical |
| Into | Iinkcukacha |
| Imbonakalo | Umgubo oMhlophe okanye oKhanyayo oMthubi |
| Isivavanyi | ≥98.0% (HPLC) |
| Ilahleko ekomisweni | ≤1.0% |
| Iintsimbi ezinzima | ≤20ppm |
| Umgangatho woVavanyo | Umgangatho woShishino |
| Ukusetyenziswa | Phakathi kwe-Irinotecan Hydrochloride (CAS: 100286-90-6) |
Iphakheji: Ibhotile, ingxowa yefoyile yeAluminiyam, igubu lekhadibhodi, 25kg/Igubu, okanye ngokwemfuno yomthengi.
Imeko yoGcino:Gcina kwizikhongozeli ezivaliweyo kwindawo epholileyo neyomileyo;Khusela ekukhanyeni, ukufuma kunye nokuhlaselwa zizinambuzane.
I-Shanghai Ruifu Chemical Co., Ltd. ngumenzi ohamba phambili kunye nomthengisi we-1-Chlorocarbonyl-4-Piperidinopiperidine Hydrochloride (CAS: 143254-82-4) enomgangatho ophezulu.Yinto ephakathi ngokuqhelekileyo kwi-synthesis ye-Irinotecan Hydrochloride (CAS: 100286-90-6), i-DNA Topoisomerase I Inhibitor.
I-lrinotecan hydrochloride, i-semi-synthetic, ephuma emanzini ephuma kwi-agent anticancer enamandla i-camptothecin, yaziswa eJapan kunyango lwemiphunga, i-ovarian, kunye nomhlaza womlomo wesibeleko.I-lrinotecan yenza umsebenzi wayo we-antitumor nge-inhibition ye-topoisomerase I, i-enzyme yeselula ebandakanyekayo ekugcineni i-topographic structure ye-DNA ngexesha lenkqubo yokuguqulela, ukukhutshelwa, kunye ne-mitosis.I-lrinotecan idlula kwi-de-esterification kwi-vivo ukuze ivelise i-metabolite esebenzayo, i-SN-38, ephindwe ka-1000 inamandla ngaphezu komzali.Nangona inetyhefu encinci kune-camptothecin, inani elibalulekileyo lezigulana kulingo lwezonyango libonise iziphumo ebezingalindelekanga ze-leukopenia, urhudo, isicaphucaphu, kunye ne-alopecia.
