1-(Cyclopropylcarbonyl)piperazine Hydrochloride CAS 1021298-67-8 Ubunyulu ≥99.0% Olaparib Intermediate Factory
I-Olaparib kunye nabaPhakathi abaNxulumeneyo:
Olaparib CAS 763113-22-0
2-Fluoro-5-Formylbenzonitrile CAS 218301-22-5
I-2-Fluoro-5-((4-oxo-3,4-dihydrophthalazin-1-yl)methyl)benzoic acid CAS 763114-26-7
1-(Cyclopropylcarbonyl)piperazine Hydrochloride CAS 1021298-67-8
3-Oxo-1,3-Dihydroisobenzofuran-1-Ylphosphonic Acid CAS 61260-15-9
Igama leMchiza | 1-(Cyclopropylcarbonyl)piperazine Hydrochloride |
Inombolo yeCAS | 1021298-67-8 |
Inombolo yeCAT | RF-PI452 |
Ubume beStokhwe | Kwi-Stock, iMveliso yoMveliso ukuya kwiiToni |
Ifomula yeemolekyuli | C8H14N2O·HCl |
Ubunzima beMolekyuli | 190.67 |
Indawo yokunyibilika | 175.0 ukuya 179.0℃ |
Ukunyibilika | Inyibilika emanzini |
Uphawu | Ruifu Chemical |
Into | Iinkcukacha |
Imbonakalo | Umgubo oMhlophe |
Ubunyulu | ≥99.0% |
Ukufuma (KF) | ≤0.50% |
Ukungacoceki Okukodwa | ≤0.50% |
Ukungcola ngokupheleleyo | ≤1.0% |
Umgangatho woVavanyo | Umgangatho woShishino |
Ukusetyenziswa | Pharmaceutical Intermediate |
Iphakheji: Ibhotile, ingxowa yefoyile yeAluminiyam, Igubu lekhadibhodi, 25kg/Igubu, okanye ngokwemfuno yomthengi.
Imeko yoGcino:Gcina kwizikhongozeli ezivaliweyo kwindawo epholileyo neyomileyo;Khusela ukukhanya kunye nokufuma.
I-1-(Cyclopropylcarbonyl) i-piperazine Hydrochloride (CAS: 1021298-67-8) isetyenziswe njenge-pharmaceutical intermediate.Ingasetyenziswa njengendawo ephakathi ye-Olaparib (CAS: 763113-22-0).I-Olaparib iyi-inhibitor enamandla kuzo zombini i-PARP-1 kunye ne-PARP-2 kwaye ivakalelwa kakhulu kwiiseli ze-KB2P ngenxa yokunyanzeliswa kokulungiswa kwe-base excision nge-PARP inhibition.I-Olaparib yamkelwa kwi-2014 yi-FDA yokunyanga umhlaza we-ovarian ophezulu.