I-1-Methylindazole-3-Carboxylic Acid CAS 50890-83-0 Ucoceko >99.0% (HPLC) Granisetron Hydrocholride Intermediate Factory Featured Image

1-Methylindazole-3-Carboxylic Acid CAS 50890-83-0 Ubunyulu >99.0% (HPLC) Granisetron Hydrocholride Intermediate Factory

Inkcazelo emfutshane:

Igama leKhemikhali: 1-Methylindazole-3-Carboxylic Acid

Izithethantonye: 1-Methyl-1H-Indazole-3-Carboxylic Acid

CAS: 50890-83-0

Ubunyulu: >99.0% (HPLC) (T)

Imbonakalo: Mhlophe ukuya kuMhlophe-Mhlophe wePowder

Phakathi kweGranisetron Hydrocholride (CAS: 107007-99-8)

Umgangatho ophezulu, iMveliso yoRhwebo

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Iimveliso ezinxulumeneyo

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Inkcazo:

Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer and supplier of 1-Methylindazole-3-Carboxylic Acid (CAS: 50890-83-0) with high quality. We can provide COA, worldwide delivery, small and bulk quantities available. If you are interested in this product, please send detailed information includes CAS number, product name, quantity to us. Please contact: alvin@ruifuchem.com

Iipropati zeMichiza:

Igama leMchiza	I-1-Methylindazole-3-Carboxylic Acid
Izithethantonye	I-1-Methyl-1H-Indazole-3-Carboxylic Acid
Ukungcola	I-Granisetron eNxulumene neCompound D;Granisetron EP Ukungcola D
Inombolo yeCAS	50890-83-0
Inombolo yeCAT	RF2673
Ubume beStokhwe	KwiSitokhwe, Umthamo weMveliso iiToni ezingama-25 ngenyanga
Ifomula yeemolekyuli	C9H8N2O2
Ubunzima beMolekyuli	176.18
Indawo yokunyibilika	213.0 ~ 218.0℃
Indawo yokubilisa	383.7±15.0℃
Ukuxinana	1.35±0.1 g/cm
Ukunyibilika emanzini	Ayinyibilikiyo emanzini.Inyibilika kwi-DMSO kunye neMethanol
Uphawu	Ruifu Chemical

Iinkcukacha:

Into	Iinkcukacha
Imbonakalo	Mhlophe ukuya kuMhlophe oMhlophe wePowder
Ubunyulu / Indlela yokuHlalutya	>99.0% (Ummandla weHPLC)
Ubunyulu / Indlela yokuHlalutya	99.0 ~ 102.5% (Titration by NaOH)
Indawo yokunyibilika	213.0 ~ 218.0℃
Ilahleko ekomisweni	<0.50%
Uthuthu lweSulfated	<0.10%
Izinto ezinxulumeneyo
Indazole Acid	<0.50%
2-Methylindazole Acid	<0.50%
Okunye Ukungcola Okukodwa	<0.50%
Ukungcola okuNxulumene ngokupheleleyo	<1.00%
I-Infrared Spectrum	Iyahambelana neSakhiwo
Proton NMR Spectrum	Iyahambelana neSakhiwo
Umgangatho woVavanyo	Umgangatho woShishino
Ukusetyenziswa	Phakathi kweGranisetron Hydrocholride (CAS: 107007-99-8)

Ukupakishwa kunye noGcino:

Iphakheji: Ibhotile, ingxowa yefoyile yeAluminiyam, 25kg/Igubu lekhadibhodi, okanye ngokwemfuno yomthengi

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Ipakethe ye-OEM: Iphakheji yesiko kunye neleyibhile ekhoyo

Ukuhanjiswa ngokukhawuleza: Ukuba ngaphakathi kwesitokhwe, ukuhanjiswa kweentsuku ezintathu kuqinisekisiwe

Ubonelelo oluzinzileyo: Gcina isitokhwe esifanelekileyo

Inkxaso yobuGcisa: Isisombululo seTekhnoloji siyafumaneka

Inkonzo yesiNtu yoHlanganiso: Isuka kwiigram ukuya kwiikhilos

Umgangatho ophezulu: Kusekwe inkqubo epheleleyo yokuqinisekisa umgangatho

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Isicelo:

I-1-Methylindazole-3-Carboxylic Acid (CAS: 50890-83-0) iphakathi kweGranisetron Hydrocholride (CAS: 107007-99-8).I-Granisetron Hydrochloride ikhetha kakhulu i-5-HT3 ye-receptor antagonist, enemiphumo emihle yokukhusela kunye neyonyango kwi-nausea kunye nokuhlanza okubangelwa yi-radiotherapy, i-chemotherapy kunye nokuhlinzwa.Izinto ezifana ne-radiotherapy, i-chemotherapy kunye nokuhlinzwa kunokubangela ukukhululwa kwe-5-HT kwiiseli ze-chromaffin zamathumbu, kunye ne-5-HT ingenza i-receptor ye-5-HT3 kwi-nerve central okanye i-vagus kwaye ibangele i-reflex yokuhlanza.Indlela yesicaphucaphu kunye nokuhlanza okulawulwa yile mveliso kukuthintelwa kwe-nausea kunye nokuhlanza ngokuchasa i-5-HT3 i-receptors kwindawo ephakathi ye-chemoreceptor kunye ne-peripheral vagal terminals.I-Granisetron Hydrochloride inokukhethwa okuphezulu, akukho mpendulo ye-extrapyramidal, i-sedation engaphezulu kunye nezinye iziphumo zecala.