I-PyBOP CAS 128625-52-5 Ubunyulu > 99.0% (HPLC) Factory Coupling Reagent

Inkcazelo emfutshane:

Igama leKhemikhali: PyBOP

CAS: 128625-52-5

Ubunyulu: >99.0% (HPLC)

Imbonakalo: Mhlophe ukuya kuMhlophe-Mhlophe wePowder

Ukudibanisa i-Reagent ye-Peptide, uMgangatho oPhezulu

Qhagamshelana: UGqr. Alvin Huang

Iselula/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com

Thumela i-imeyile kuthi

Iinkcukacha zeMveliso

Iimveliso ezinxulumeneyo

Iithegi zeMveliso

Inkcazo:

I-Shanghai Ruifu Chemical Co., Ltd. ngumenzi ohamba phambili wePyBOP (CAS: 128625-52-5) enomgangatho ophezulu.I-Ruifu ibonelela ngothotho lwee-reagents ezikhuselayo kunye ne-coupling reagents.I-Ruifu inokubonelela ngenkonzo yehlabathi jikelele, ixabiso elikhuphisanayo, amanani amancinci kunye nesixa esikhulu esikhoyo.Thenga iPyBOP,Please contact: alvin@ruifuchem.com

Iipropati zeMichiza:

Igama leMchiza	I-PyBOP
Izithethantonye	1H-Benzotriazol-1-yloxytripyrrolidinophosphonium Hexafluorophosphate;(Benzotriazol-1-yloxy)tripyrrolidinophosphonium Hexafluorophosphate;1H-Benzotriazol-1-yloxytri(1-pyrrolidinyl)phosphonium Hexafluorophosphate
Ubume beStokhwe	Kwi-Stock, iMveliso yeMisa
Inombolo yeCAS	128625-52-5
Ifomula yeemolekyuli	I-C18H28F6N6OP2
Ubunzima beMolekyuli	520.40 g/mol
Indawo yokunyibilika	150.0 ~ 158.0℃
Ukuxinana	1.438 kwi-20℃
Inovakalelo	UkuKhanya Kunovakalelo, Ubunobuzaza bokufuma, Bunobuva ubushushu
Ukunyibilika	Inyibilika kwiChloroform
Ugcino Temp.	Indawo epholileyo neyomileyo (2~8℃)
I-COA kunye ne-MSDS	Iyafumaneka
Udidi	Coupling Reagents
Uphawu	Ruifu Chemical

Iinkcukacha:

Izinto	ImiGangatho yokuHlola	Iziphumo
Imbonakalo	Mhlophe ukuya kuMhlophe-Mhlophe wePowder	Iyahambelana
Indawo yokunyibilika	150.0 ~ 158.0℃	154.0 ~ 158.0℃
Ilahleko ekomisweni	<0.50%	0.09%
Iintsimbi ezinzima (Pb)	≤20ppm	<20ppm
Ubunyulu / Indlela yokuHlalutya	>99.0% (HPLC)	99.8%
Ukucaca kwesisombululo	I-1 mmole kwi-2 ml ye-DMF ecacileyo isisombululo	Iyahambelana
I-Infrared Spectrum	Iyahambelana neSakhiwo	Iyahambelana
Proton NMR Spectrum	Iyahambelana neSakhiwo	Iyahambelana
Ukuqukumbela	Imveliso ivavanyiwe kwaye iyahambelana neenkcukacha ezinikiweyo

Ukupakishwa/uGcino/Ukuhambisa ngenqanawe:

Umqulu:Ibhotile, ingxowa yefoyile yeAluminiyam, 25kg/Igubu lekhadibhodi, okanye ngokwemfuno yomthengi.
Imeko yoGcino:Gcina kwizikhongozeli ezivaliweyo kwindawo yokugcina impahla epholileyo neyomileyo (2~8℃) kude nezinto ezingahambelaniyo.Khusela ukukhanya kunye nokufuma.Ayihambelani ne-oxidizing agents kunye namanzi.
Ukuhambisa ngenqanawe:Zisa kwihlabathi liphela ngeFedEx / DHL Express.Ukubonelela ngokukhawuleza nangokuthembekileyo.

Indlela yoVavanyo:

1. Izixhobo kunye nee-reagents: I-LC-10AVP i-chromatograph yolwelo ephezulu yokusebenza;SPD-10AVP umtshini;I-acetonitrile (i-chromatographic ecocekileyo)
2. Amanyathelo okusebenza: ngokumiselwa kolwelo oluphezulu lwechromatography.
a.Iimeko zeChromatographic: i-octadecylsilane edibeneyo ye-silica gel yasetyenziswa njenge-filler (150 * 4.6mm * 5.0μm);Ukusebenzisa i-Acetonitrile: Amanzi = 3: 2 njengesigaba seselula;Ubude bokubona ubude be-258nm.Ubushushu bekholamu: 25℃;Izinga lokuhamba: 0.5ml / min;Inani leeplati zeethiyori kufuneka lingabi ngaphantsi kwe-2000 ngokweyona nto iphambili yePyBOP.
b.Indlela yokumisela: Thatha le mveliso kwaye ungeze isigaba seselula ukwenza isisombululo esiqulethe i-PyBOP 100ug nge-1ml njengesisombululo semveliso yovavanyo.I-20μl yesisombululo sovavanyo yafakwa kwi-chromatograph, kwaye i-chromatogram yabhalwa ngamaxesha angama-2 ixesha lokugcinwa kwenqununu yenqununu.
c.Iziphumo: Le mveliso ibalwa njengemveliso eyomileyo, equkethe akukho ngaphantsi kwe-99.0% yePyBOP.

Izinto eziluncedo:

Umthamo owaneleyo: Izixhobo ezaneleyo kunye namagcisa

Inkonzo yobuNgcali: Inkonzo enye yokuyeka ukuthenga

Ipakethe ye-OEM: Iphakheji yesiko kunye neleyibhile ekhoyo

Ukuhanjiswa ngokukhawuleza: Ukuba ngaphakathi kwesitokhwe, ukuhanjiswa kweentsuku ezintathu kuqinisekisiwe

Ubonelelo oluzinzileyo: Gcina isitokhwe esifanelekileyo

Inkxaso yobuGcisa: Isisombululo seTekhnoloji siyafumaneka

Inkonzo yesiNtu yoHlanganiso: Isuka kwiigram ukuya kwiikhilos

Umgangatho ophezulu: Kusekwe inkqubo epheleleyo yokuqinisekisa umgangatho

FAQ:

Ukuthenga njani?Nceda uqhagamshelaneDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com

Amava Eminyaka Eli-15?Sineminyaka engaphezu kwe-15 yamava ekwenziweni nasekuthumeleni kumazwe angaphandle uluhlu olubanzi oluphezulu lwamayeza aphakathi okanye amachiza alungileyo.

Iimarike eziphambili?Thengisa kwimarike yasekhaya, eMntla Melika, eYurophu, eIndiya, eKorea, eJapan, eOstreliya, njl.

Iingenelo?Umgangatho ophezulu, ixabiso elifikelelekayo, iinkonzo zengcali kunye nenkxaso yobugcisa, ukuhanjiswa ngokukhawuleza.

UmgangathoIsiqinisekiso?Inkqubo yokulawula umgangatho ongqongqo.Izixhobo zobuchwephesha zokuhlalutya ziquka i-NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, njl.

Iisampulu?Uninzi lweemveliso zibonelela ngeesampulu zasimahla zokuvavanya umgangatho, iindleko zokuthumela kufuneka zihlawulwe ngabathengi.

Factory Audit?Uphicotho-zincwadi lwasefektri wamkelekile.Nceda wenze idinga kwangaphambili.

MOQ?Akukho MOQ.Umyalelo omncinci wamkelekile.

Ixesha lokuzisa? Ukuba ngaphakathi kwesitokhwe, ukuhanjiswa kweentsuku ezintathu kuqinisekisiwe.

Ezothutho?Nge-Express (FedEx, DHL), ngoMoya, ngoLwandle.

Amaxwebhu?Emva kwenkonzo yokuthengisa: I-COA, i-MOA, i-ROS, i-MSDS, njl.

Udibaniso lweSiko?Inokubonelela ngeenkonzo zesiko lokudibanisa ukuze zilungele iimfuno zakho zophando.

Immimiselo yokuhlawula?I-invoyisi yeProforma iya kuthunyelwa kuqala emva kokuqinisekiswa kwe-odolo, efakwe kwiinkcukacha zethu zebhanki.Intlawulo nge-T / T (i-Telex Transfer), i-PayPal, i-Western Union, njl.

128625-52-5 - Umngcipheko kunye noKhuseleko:

Iimpawu zeHazard Xi - Irritant
Iikhowudi zoMngcipheko
I-R37/38 - Iyacaphukisa inkqubo yokuphefumla kunye nolusu.
I-R44 - Umngcipheko wogqabhuko-dubulo ukuba uthe watshisa uvalelwe
R36/37/38 - Ukucaphukisa emehlweni, inkqubo yokuphefumla kunye nolusu.
Inkcazelo yoKhuseleko
S26 - Xa udibana namehlo, hlambulula ngokukhawuleza ngamanzi amaninzi kwaye ufune iingcebiso zonyango.
S36 - Nxiba iimpahla ezifanelekileyo zokukhusela.
I-S24/25 - Gwema ukudibana nolusu kunye namehlo.
I-S37/39 - Nxiba iiglavu ezifanelekileyo kunye nokukhusela amehlo / ubuso
Ii-ID ze-UN UN 1325 4.1/PG 2
WGK eJamani 3
FLUKA BRAND F IIKHOWUDI 8-10-21
Ikhowudi yeHS 2933990099
I-Hazard Note irritant

Isicelo:

I-1H-Benzotriazol-1-yloxytripyrrolidinophosphonium Hexafluorophosphate (PyBOP) (i-CAS: i-128625-52-5) yenye yezona zinto zilungele kakhulu i-peptide coupling reagents ezisetyenziswe kwi-peptide yesigaba esiqinileyo synthesis ngaphandle kwe-carcinogenic by-products.Ikwasetyenziswa njengento ebambeleyo (benzotriazol-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate (BOP) reagent.Inokusebenza kwakhona okufana ne-BOP, kodwa imveliso yayo ayinayo i-carcinogenic ephezulu.I-PyBOP ifanelekile ngokukodwa kwi-soli-phase peptide synthesis, igwema i-racemization.Ngokwahlukileyo kwi-uronium-based coupling reagents, i-PyBOP ayenzi i-guanidinated byproducts xa isetyenziswe ngokugqithisileyo.Oku kuyenza ibe luncedo kwiintshukumo zokujikwa kweqhekeza kunye neebhayisikile zentloko ukuya kumsila.
I-analogues ye-BOP yokudibanisa i-reagents, kodwa musa ukwenza i-carcinogens i-HMPA yimveliso ephuma kuyo.Ingasetyenziswa endaweni ye-BOP kwi-peptide synthesis ngaphandle kokulahlekelwa kokusebenza kakuhle kokudibanisa.Iimpendulo zokudibanisa zikhawuleza, ziphantse zigqitywe kwimizuzu embalwa.Ngokukodwa kuluncedo kumanyathelo okuhamba ngebhayisikile ukuze kusebenze i-amino acid ethintelweyo.
I-Reagent ye: Ukudityaniswa kwe-oligonucleotides enye ephawulwe nge-fluoresce phezu komxube ohambelanayo;Isizukulwana sezibophelelo zeekhemikhali eziphazamisayo ze-endocrine;I-Cycloaddition ukuya kwiiconjugates ze-peptide ezininzi ezidityanisiweyo.