1,3,5-Tri-O-benzoyl-D-Ribofuranose CAS 22224-41-5 Ubunyulu ≥99.0% Clofarabine Intermediate High Purity

Inkcazelo emfutshane:

Igama leKhemikhali: 1,3,5-Tri-O-benzoyl-D-Ribofuranose

CAS: 22224-41-5

Imbonakalo: I-White okanye i-Off-White Powder

Ubunyulu: ≥99.0%

Phakathi kweClofarabine (CAS: 123318-82-1) kunyango lwaBantwana abane-Acute Lymphoblastic Leukemia (ALL)

Inquiry: alvin@ruifuchem.com

Thumela i-imeyile kuthi

Iinkcukacha zeMveliso

Iimveliso ezinxulumeneyo

Iithegi zeMveliso

Inkcazo:

Ubonelelo ngezoRhwebo lweClofarabine oluNxulumene neMiphakathi:
I-Clofarabine CAS: 123318-82-1
I-2-Deoxy-2-fluoro-1,3,5-tri-O-benzoyl-α-D-arabinofuranose CAS: 97614-43-2
I-β-D-Ribofuranose 1-Acetate 2,3,5-Tribenzoate CAS: 6974-32-9
1,3,5-Tri-O-benzoyl-D-Ribofuranose CAS: 22224-41-5
2,6-Dichloropurine CAS: 5451-40-1

Iipropati zeMichiza:

Igama leMchiza	1,3,5-Tri-O-benzoyl-D-Ribofuranose
Inombolo yeCAS	22224-41-5
Inombolo yeCAT	RF-PI223
Ubume beStokhwe	Kwi-Stock, iMveliso yoMveliso ukuya kwiiToni
Ifomula yeemolekyuli	C26H22O8
Ubunzima beMolekyuli	462.45
Indawo yokunyibilika	125.0-129.0℃(lit.)
Ukunyibilika	Ayinyibilikiyo emanzini
Uphawu	Ruifu Chemical

Iinkcukacha:

Into	Iinkcukacha
Imbonakalo	Umgubo oMhlophe okanye oMhlophe
Ubunyulu	≥99.0%
Ilahleko ekomisweni	≤1.00%
Ukungacoceki okuphezulu okukodwa	≤0.50%
Ukungcola ngokupheleleyo	≤1.00%
Iintsimbi ezinzima	≤20ppm
Umgangatho woVavanyo	Umgangatho woShishino
Ukusetyenziswa	Umbindi weClofarabine (CAS: 123318-82-1)

Ukupakishwa kunye noGcino:

Iphakheji: Ibhotile, ingxowa yefoyile yeAluminiyam, igubu lekhadibhodi, 25kg/Igubu, okanye ngokwemfuno yomthengi.

Imeko yoGcino:Gcina kwizikhongozeli ezivaliweyo kwindawo epholileyo neyomileyo;Khusela ekukhanyeni, ukufuma kunye nokuhlaselwa zizinambuzane.

Izinto eziluncedo:

FAQ:

Isicelo:

I-1,3,5-Tri-O-benzoyl-D-Ribofuranose (i-CAS: 22224-41-5) yinto yokuqala ye-nucleoside synthesis.Ingasetyenziselwa njengendawo ephakathi kweClofarabine (CAS: 123318-82-1).I-Clofarabine yinoveli ye-purine nucleoside anticancer yamachiza iphuhliswe ngempumelelo yinkampani ye-biopharmaceutical eyi-Top10 yase-United States-Genzyme Corporation ngamagama orhwebo athi “Clofarabine”.Ngomhla wama-28 kuDisemba, i-2004 i-FDA yasebenzisa i-fast-track ukuze yamkelwe i-Clofarabine kwisicelo kubantwana abane-refractory okanye i-relapsed acute lymphocytic leukemia.I-Clofarabine idibanisa iingenelo zeFludarabine kunye neCladribine ukuvimbela zombini i-DNA polymerase kunye ne-RIbonucleic acid reductase.Okwangoku kuphela kwechiza elilungele unyango lwe-leukemia yabantwana.Uphononongo luye lwabonisa ukuba ukusebenza kwayo konyango kuphezulu kakhulu, kwaye ireyithi yokuphendula iyonke yezigulane ezingenampendulo kwi-chemotherapy ezimbini eziqhelekileyo yi-31%.Kwaye ukunyamezela ngomonde kulungile, akukho kusabela okubi okungalindelekanga;Ineepropati ezinokuba ne-antitumor ebanzi.