(1S,2S,3R,5S)-(+)-2,3-Pinanediol CAS 18680-27-8 ee ≥99.0% Ubunyulu ≥99.0% Bortezomib Intermediate High Purity
Ukubonelela nge-Bortezomib eNxulumene ne-Intermediates kunye ne-High Purity
(1S,2S,3R,5S)-(+)-2,3-Pinanediol CAS 18680-27-8
(1R,2R,3S,5R)-(-)-2,3-Pinanediol CAS 22422-34-0
I-Bortezomib CAS 179324-69-7
| Igama leMchiza | (1S,2S,3R,5S)-(+)-2,3-Pinanediol |
| Izithethantonye | (1S,2S,3R,5S)-2,6,6-Trimethylbicyclo[3.1.1]heptane-2,3-diol |
| Inombolo yeCAS | 18680-27-8 |
| Inombolo yeCAT | RF-CC290 |
| Ubume beStokhwe | Kwi-Stock, iMveliso yoMveliso ukuya kwiiToni |
| Ifomula yeemolekyuli | C10H18O2 |
| Ubunzima beMolekyuli | 170.25 |
| Ukunyibilika | I-Chloroform, iToluene |
| Imeko yokuthumela ngenqanawa | Ithunyelwe Ngaphantsi Kweqondo Lobushushu Le-Ambient |
| Uphawu | Ruifu Chemical |
| Into | Iinkcukacha |
| Imbonakalo | Mhlophe ukuya kuMhlophe-Obumhlophe obukhazimlisiweyo |
| Indawo yokunyibilika | 56.0 ~ 59.0℃ |
| Ilahleko ekomisweni | ≤0.50% |
| Intsalela kwi-Ignition | ≤0.50% |
| Ukugqithiswa kwe-Enantiomeric | ee≥99.0% |
| Ubunyulu / Indlela yokuHlalutya | ≥99.0% (GC) |
| Ukujikeleziswa okuthe ngqo [α]20/D | +8.5° ukuya +9.5° (C=6.5, iToluene) |
| I-Infrared Spectrum | Iyahambelana |
| Umgangatho woVavanyo | Umgangatho woShishino |
| Ukusetyenziswa | IiCompounds zeChiral;abaPhakathi bamayeza;I-Bortezomib ePhakathi |
Iphakheji: Ibhotile, ingxowa yefoyile yeAluminiyam, Igubu lekhadibhodi, 25kg/Igubu, okanye ngokwemfuno yomthengi.
Imeko yoGcino:Gcina kwizikhongozeli ezivaliweyo kwindawo epholileyo neyomileyo;Khusela ekukhanyeni, ukufuma kunye nokuhlaselwa zizinambuzane.
I-Shanghai Ruifu Chemical Co., Ltd. ngumenzi ohamba phambili kunye nomthengisi we (1S,2S,3R,5S)-(+)-2,3-Pinanediol (CAS 18680-27-8) kunye nomgangatho ophezulu, osetyenziswa ngokubanzi kwizinto eziphilayo. i-synthesis, i-synthesis ye-pharmaceutical intermediates kunye ne-fine chemical synthesis.
I-Shanghai Ruifu Chemical Co., Ltd. idlala indima ebalulekileyo kwi-chemistry ye-chiral, inkampani izinikele ekuveliseni i-chiral compounds.Iimveliso zethu zinconywa ngokubanzi ngabathengi.
(1S, 2S, 3R, 5S) - (+) -2,3-Pinanediol (CAS 18680-27-8), i-reagent ye-Chiral eluncedo esetyenziswe kwi-synthesis ye-homochiral α-hydroxyketones kunye nesisombululo se-prolineboronate esters.Kwakhona kuluncedo lwangaphambili kwi-chiral allyl boronate esetyenziselwa ukulungiswa kwe-chiral β-hydroxyallylsilanes.
(1S,2S,3R,5S)-(+)-2,3-Pinanediol (CAS 18680-27-8) i-Intermediate ye-Bortezomib (CAS 179324-69-7) kunyango lwe-Multiple Myeloma.I-Bortezomib, i-ubiquitin proteasome enamandla (26S) inhibitor (Ki = 0.6 nM), yasungulwa e-US njengonyango lwe-myeloma eninzi.Le proteasome iyadingeka ekuthotyweni kweproteolytic uninzi lweeproteni zeselula kwaye ikhona kuzo zonke iiseli.Kuyimfuneko ekulawuleni iinkqubo ezivuthayo, ukulawulwa komjikelo weeseli kunye nokubonakaliswa kofuzo kwaye kujoliswe kuyo inoveli kunyango lomhlaza.
