I-2-Butyl-4-Chloro-5-Formylimidazole (BCFI) CAS 83857-96-9 Losartan Potassium Intermediate Factory
Ukubonelela ngeLosartan Potassium kunye neMidiya eNxulumeneyo
I-Losartan Potassium CAS 124750-99-8
I-2-Butyl-4-Chloro-5-Formylimidazole (BCFI) CAS 83857-96-9
Umgangatho ophezulu, iMveliso yoRhwebo
Igama leMchiza | 2-Butyl-4-chloro-5-formylimidazole |
Izithethantonye | I-BCFI;I-2-Butyl-5-chloro-1H-imidazole-4-carboxaldehyde |
Inombolo yeCAS | 83857-96-9 |
Inombolo yeCAT | RF-PI319 |
Ubume beStokhwe | Kwi-Stock, iMveliso yoMveliso ukuya kwiiToni |
Ifomula yeemolekyuli | I-C8H11ClN2O |
Ubunzima beMolekyuli | 186.64 |
Ukuxinana | 1.240 |
Ukunyibilika | Inyibilika kwiMethanol kunye neChloroform;Inyibilika kancinane emanzini |
Uphawu | Ruifu Chemical |
Into | Iinkcukacha |
Imbonakalo | Umgubo oMthubi oKhanyayo ukuya koMthubi |
Ukuchongwa | Kufuneka Ingqinelane noMgangatho weReferensi |
Indawo yokunyibilika | 96.0~99.0℃(lit.) |
Isiqulatho sokufuma (KF) | ≤0.50% |
Imidazolol | Ayifunyanwa |
Valeronitile | ≤0.15% |
Ukungcola okukodwa | ≤0.15% |
Ukungcola ngokupheleleyo | ≤1.0% |
Ubunyulu / Indlela yokuHlalutya | ≥99.0% (nge-HPLC) |
Umgangatho woVavanyo | Umgangatho woShishino |
Ukusetyenziswa | Phakathi kweLosartan Potassium (CAS 124750-99-8) I-Antihypertensive |
Iphakheji: Ibhotile, ingxowa yefoyile yeAluminiyam, igubu lekhadibhodi, 25kg/Igubu, okanye ngokwemfuno yomthengi.
Imeko yoGcino:Gcina kwizikhongozeli ezivaliweyo kwindawo epholileyo neyomileyo;Khusela ekukhanyeni, ukufuma.
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I-2-Butyl-4-chloro-5-formylimidazole (BCFI) (i-CAS 83857-96-9) iphakathi kwe-Losartan Potassium (i-CAS 124750-99-8), i-angiotensin II receptor antagonist.I-Losartan Potassium yityuwa ye-potassium ye-losartan enomsebenzi we-antihypertensive, esetyenziswa kakhulu kunyango lwe-high blood pressure (uxinzelelo lwegazi) kunye ne-nephropathy yesifo seswekile.Isebenza ngokuphumza imithambo yegazi ukuze igazi likwazi ukuhamba lula.Ikwayasebenza ekuncedeni ukukhusela izintso kumonakalo owenziwe sisifo seswekile kunye nokunciphisa imingcipheko ye-stroke kwizigulana ezinoxinzelelo lwegazi kunye nokwandiswa kwe-myocardial.Ngaphandle koko, uphononongo lwakutsha nje lucebise ukuba i-losartan iluncedo ekubuyiseleni umva ukungasebenzi kakuhle okunxulumene nobudala ekugcineni uxinzelelo lwegazi oluqhelekileyo kunye nokusetyenziswa kwamandla eselula kwi-mitochondria kwaye inokusetyenziswa ukunyanga i-hypertrophy ye-ventricular yasekhohlo.