I-2-(Chloromethyl)-4-Methylquinazoline CAS 109113-72-6 iLinagliptin ePhakathi yoBusulungekileyo ≥99.0% (HPLC)

Inkcazelo emfutshane:

Igama leKhemikhali: 2-(Chloromethyl) -4-Methylquinazoline

CAS: 109113-72-6

Ubunyulu: ≥99.0% (HPLC)

Imbonakalo: Mthubi oMthubi ukuya kwiPowder emdaka

I-Intermediate ye-Linagliptin (i-CAS: 668270-12-0) yonyango lwabantu abadala abane-type 2 yesifo sikashukela.

Umgangatho ophezulu, iMveliso yoRhwebo

E-Mail: alvin@ruifuchem.com


Iinkcukacha zeMveliso

Iimveliso ezinxulumeneyo

Iithegi zeMveliso

Inkcazo:

Iipropati zeMichiza:

Igama leMchiza I-2-(Chloromethyl) -4-Methylquinazoline
Izithethantonye ILinagliptin ePhakathi A
Inombolo yeCAS 109113-72-6
Inombolo yeCAT RF-PI498
Ubume beStokhwe Kwi-Stock, iMveliso yoMveliso ukuya kwiiToni
Ifomula yeemolekyuli I-C10H9ClN2
Ubunzima beMolekyuli 192.64
Ukuxinana 1.251
Uphawu Ruifu Chemical

Iinkcukacha:

Into Iinkcukacha
Imbonakalo Umgubo oMthubi oMthubi ukuya kwiPowder emdaka
Isazisi A Isampulu ye-IR kufuneka ihambelane ne-spectrum eqhelekileyo
Isazisi B Ixesha lokugcinwa kwencopho yomgaqo wesampulu kufuneka ihambelane nomgangatho
Ukunyibilika Inyibilika kwiMethylene Chloride;Ayinyibilikiyo emanzini
Ubunyulu / Indlela yokuHlalutya ≥99.0% (HPLC)
Indawo yokunyibilika 60.0 ukuba 65.0℃
Amanzi (KF) ≤0.50%
Intsalela kwi-Ignition ≤0.50%
Izinto ezinxulumeneyo  
Ukungacoceki Okukodwa ≤0.30%
Ukungcola ngokupheleleyo ≤1.0%
Umgangatho woVavanyo Umgangatho woShishino
Ukusetyenziswa Esiphakathi kwiLinagliptin (CAS: 668270-12-0)

Ukupakishwa kunye noGcino:

Iphakheji: Ibhotile, ingxowa yefoyile yeAluminiyam, 25kg/Igubu lekhadibhodi, okanye ngokwemfuno yomthengi.

Imeko yoGcino:Gcina kwizikhongozeli ezivaliweyo kwindawo epholileyo neyomileyo;Khusela ukukhanya kunye nokufuma.

Izinto eziluncedo:

1

FAQ:

Isicelo:

I-2-(Chloromethyl) -4-Methylquinazoline (i-CAS: 109113-72-6) isetyenziswe njengendawo ephakathi yokulungiswa kweLinagliptin (CAS: 668270-12-0), kunye nokungcola kwayo.I-Linagliptin, ethengiswa phantsi kwegama lebrendi iTradjenta phakathi kwezinye, liyeza elisetyenziselwa ukunyanga isifo seswekile sohlobo lwesi-2. Ngokuqhelekileyo ayithandwa kakhulu kune-metformin kunye ne-sulfonylureas njengonyango lokuqala.Isetyenziswa kunye nokuzilolonga kunye nokutya.Ayikhuthazwa kuhlobo lwe-1 yeswekile.Isebenza ngokwandisa imveliso ye-insulin kunye nokunciphisa ukuveliswa kweglucagon yi-pancreas.I-Linagliptin yamkelwa ukuba isetyenziswe kwezonyango e-United States ngo-2011. I-Linagliptin inamandla kakhulu, ikhetha i-dipeptidyl peptidase-4 (DPP-4) inhibitor ene-IC50 ye-1 nM.

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