2′-Fluoroacetophenone CAS 445-27-2 Ubunyulu > 98.0% (GC)
I-Shanghai Ruifu Chemical Co., Ltd. ngumenzi ohamba phambili kunye nomthengisi we-2'-Fluoroacetophenone (CAS: 445-27-2) enomgangatho ophezulu.Sinokubonelela nge-COA, ukuhanjiswa kwehlabathi jikelele, ubuninzi obuncinci kunye nobuninzi obukhoyo.Ukuba unomdla kule mveliso, nceda uthumele ulwazi oluneenkcukacha lubandakanya inombolo ye-CAS, igama lemveliso, ubuninzi kuthi.Please contact: alvin@ruifuchem.com
Igama leMchiza | I-2'-Fluoroacetophenone |
Izithethantonye | o-Fluoroacetophenone;I-2-Fluoroacetophenone;I-1-(2-Fluorophenyl)ithanone;1-(2-Fluorophenyl)than-1-enye |
Inombolo yeCAS | 445-27-2 |
Inombolo yeCAT | RF2963 |
Ubume beStokhwe | KwiSitokhwe, Umthamo weMveliso iiToni ezingama-20 ngenyanga |
Ifomula yeemolekyuli | C8H7FO |
Ubunzima beMolekyuli | 138.14 |
Indawo yokubilisa | 82.0~83.0℃/10 mmHg |
Indawo yokuflasha | 61℃(141°F) |
Ukunyibilika | Inyibilika kwiAcetone, Chloroform, Dichloromethane, Ethanol, Ethyl Acetate kunye neMethanol |
IKlasi yeeNgozi | Iyacaphukisa |
Iqela lokuPakisha | III |
Ikhowudi ye-HS | 29147090 |
Uphawu | Ruifu Chemical |
Into | Iinkcukacha |
Imbonakalo | AbunaMbala ukuya kuLwelo oluKhanyayo |
Ubunyulu / Indlela yokuHlalutya | >98.0% (GC) |
Ubuninzi (20℃) | 1.139~1.142 |
Refractive Index n20/D | 1.507~1.509 |
I-1 H NMR Spectrum | Ukungqinelana Nolwakhiwo |
I-LCMS | Ukungqinelana Nolwakhiwo |
Amanzi (nguKarl Fischer) | <0.50% |
Ukungcola ngokupheleleyo | <2.00% |
Umgangatho woVavanyo | Umgangatho woShishino |
Ukusetyenziswa | Phakathi kwezamayeza;Vonoprazan Fumarate Intermediate / Ukungcola |
Iphakheji: Ibhotile eFluorinated, 25kg/Drum, 200kg/Drum, okanye ngokwemfuno yomthengi
Imeko yoGcino:Gcina kwizikhongozeli ezivaliweyo kwindawo epholileyo neyomileyo.Khusela ukukhanya kunye nokufuma.Gcina kude neearhente ezinamandla oxidizing.
Ukuthenga njani?Nceda uqhagamshelaneDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
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I-2'-Fluoroacetophenone (i-CAS: 445-27-2) yindawo ephakathi kweyeza, engasetyenziselwa njengento yokuqala ukudibanisa i-Vonoprazan Fumarate (i-CAS: 1260141-27-2).I-Vonoprazan Fumarate (i-Takecab®), efunyenwe kwaye yaphuhliswa ngu-Takeda no-Otsuka, yavunywa yi-PMDA yaseJapan ngoDisemba 2014, kwaye ibonakaliswe kunyango lwesilonda sesisu, isilonda se-duodenal kunye ne-reflux esophagitis.I-Vonoprazan Fumarate inendlela inoveli yesenzo esibizwa ngokuba yi-potassium-competitive acid blockers, ekhuphisana ngokunqanda ukubophelela kwe-potassium ions kwi-H +, K + -ATPase (eyaziwa ngokuba yipompo yeproton) kwinqanaba lokugqibela le-gastric acid secretion in gastric parietal cells.I-Vonoprazan ayivimbeli umsebenzi we-Na +, i-K + -ATPase nakwizigxina ze-500 ngamaxesha aphakamileyo ngaphezu kwexabiso labo le-IC50 ngokumelene ne-gastric H +, K + -ATPase umsebenzi.Ngaphezu koko, iyeza alichatshazelwa yi-gastric secretory state, ngokungafaniyo neePPIs.