I-2-Methyltryptamine CAS 2731-06-8 Ubunyulu > 99.0% (HPLC) Panobinostat Umgangatho oPhakamileyo weFactory

Inkcazelo emfutshane:

Igama leKhemikhali: 2-Methyltryptamine

CAS: 2731-06-8

Ubunyulu: >99.0% (HPLC)

Imbonakalo: I-Brown Solid

Phakathi kwePanobinostat (CAS: 404950-80-7)

Umgangatho ophezulu, iMveliso yoRhwebo

E-Mail: alvin@ruifuchem.com


Iinkcukacha zeMveliso

Iimveliso ezinxulumeneyo

Iithegi zeMveliso

Inkcazo:

Ubonelelo loMvelisi ngoMgangatho oPhezulu, iMveliso yoRhwebo
Igama leKhemikhali: 2-Methyltryptamine CAS: 2731-06-8

Iipropati zeMichiza:

Igama leMchiza 2-Methyltryptamine
Izithethantonye 2-Methylindole-3-Ethylamine;2-(2-Methyl-1H-indol-3-yl) ethanamine;3-(2-Aminoethyl)-2-Methylindole
Inombolo yeCAS 2731-06-8
Inombolo yeCAT RF-PI1480
Ubume beStokhwe Kwi-Stock, iMveliso yoMveliso ukuya kwiiToni
Ifomula yeemolekyuli C11H14N2
Ubunzima beMolekyuli 174.25
Indawo yokunyibilika 106.0 ukuba 110.0℃
Indawo yokubilisa 177℃/1.5mmHg(lit.)
Uphawu Ruifu Chemical

Iinkcukacha:

Into Iinkcukacha
Imbonakalo Umdaka oqinileyo
Ubunyulu / Indlela yokuHlalutya >99.0% (Ummandla weHPLC)
1-HNMR Ukungqinelana Nolwakhiwo
Ilahleko ekomisweni <1.00%
Ukungacoceki Okukodwa <0.50%
Ukungcola ngokupheleleyo <1.00%
Iintsimbi ezinzima (njenge Pb) <20ppm
Umgangatho woVavanyo Umgangatho woShishino
Ukusetyenziswa abaPhakathi bamayeza;I-Panobinostat ePhakathi

Ukupakishwa kunye noGcino:

Iphakheji: Ibhotile, ingxowa yefoyile yeAluminiyam, 25kg/Igubu lekhadibhodi, okanye ngokwemfuno yomthengi.

Imeko yoGcino:Gcina kwizikhongozeli ezivaliweyo kwindawo epholileyo neyomileyo;Khusela ukukhanya kunye nokufuma.

Izinto eziluncedo:

1

FAQ:

Isicelo:

I-2-Methyltryptamine (i-CAS: i-2731-06-8) yinto ephambili yokuqala kwi-synthesis ye-Panobinostat (LBH589) (i-CAS: 404950-80-7).I-Panobinostat yi-inhibitor enamandla yazo zonke i-histone deacetylases (i-HDACs), kunye namaxabiso e-Ki ukusuka kwi-0.6 ukuya kwi-31 nM ye-HDAC1-11.Ngesi senzo, kukhokelela kwi-acetylation yoluhlu lweeproteni zeselula, ezikhokelela ekubanjweni komjikelo weeseli kunye ne-apoptosis kwiiseli zomhlaza.I-Panobinostat yi-HDAC inhibitor yokuqala eyavunywa yi-FDA kunyango lwe-myeloma emininzi.I-Panobinostat ithengiswa njenge-Farydak, isetyenziswe ngokudibanisa ne-Bortezomib (CAS: 179324-69-7) kunye ne-Dexamethasone (i-CAS: i-50-02-2) ukunyanga i-myeloma ephindaphindiweyo emva kokunyangwa kwangaphambili kunye ne-Bortezomib kunye ne-immunomodulator.

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