2-(p-Tolyl)benzoic Acid CAS 7148-03-0 Purity >98.0% (GC) Sartan APIs Intermediate Factory
Ubonelelo lweMichiza yeRuifu yeTelmisartan ePhakathi ngoKucoceka okuPhezulu
I-Telmisartan CAS 144701-48-4
Methyl 2-(p-Tolyl)benzoate CAS 114772-34-8
2-(p-Tolyl)benzoic Acid CAS 7148-03-0
Telmisartan Benzimidazole Acid CAS 152628-03-0
Telmisartan Methyl Ester CAS 528560-93-2
Methyl 2-[4-(Bromomethyl)phenyl]benzoate CAS 114772-38-2
Methyl 4-(Butyrylamino)-3-Methyl-5-Nitrobenzoate CAS 152628-01-8
2-n-Propyl-4-Methyl-6-(1-Methylbenzimidazole-2-yl)benzimidazole CAS 152628-02-9
Igama leMchiza | 2-(p-Tolyl)benzoic Acid |
Izithethantonye | 4'-Methylbiphenyl-2-Carboxylic Acid;2-(4-Methylphenyl) benzoic Acid |
Inombolo yeCAS | 7148-03-0 |
Inombolo yeCAT | RF-PI1884 |
Ubume beStokhwe | Kwi-Stock, iMveliso yoMveliso ukuya kwiiToni |
Ifomula yeemolekyuli | C14H12O2 |
Ubunzima beMolekyuli | 212.25 |
Uphawu | Ruifu Chemical |
Into | Iinkcukacha |
Imbonakalo | IMhlophe ukuya kwiCrystal eNtuthulu ngokuKakhulu okanye uPowder |
Ubunyulu / Indlela yokuHlalutya | >98.0% (GC) |
Indawo yokunyibilika | 148.0 ~ 152.0℃ |
Ilahleko ekomisweni | <1.00% |
Ukungcola ngokupheleleyo | <2.00% |
Ukunyibilika kwiMethanol | Phantse Ukungafihli |
Proton NMR Spectrum | Iyahambelana noLwakhiwo |
Umgangatho woVavanyo | Umgangatho woShishino |
Ukusetyenziswa | I-Intermediate ye-Sartan APIs;I-Telmisartan |
Iphakheji: Ibhotile, ingxowa yefoyile yeAluminiyam, 25kg/Igubu lekhadibhodi, okanye ngokwemfuno yomthengi
Imeko yoGcino:Gcina kwizikhongozeli ezivaliweyo kwindawo epholileyo neyomileyo;Khusela ukukhanya kunye nokufuma
I-2-(p-Tolyl) i-benzoic Acid (i-CAS: 7148-03-0) yinto ebalulekileyo ephakathi kwi-sartan APIs.I-Sartan antihypertensive drug luhlobo olutsha lwamachiza oluqhele ukusetyenziswa kunyango lwezonyango loxinzelelo lwegazi, kwaye sisishunqulelo se-angiotensin II receptor antagonist.Xa sithetha ngokuthelekisa, la machiza anefuthe eliphezulu le-antihypertensive kunye neziphumo ebezingalindelekanga ezimbalwa.1. I-Losartan: Eli lelona chiza lokuqala le-Sartan le-antihypertensive lisetyenziswe kunyango lwezonyango, kwaye kunokuthiwa limele olu hlobo lwechiza.Ngokuqhelekileyo, izigulane kufuneka zikhethe umthamo ofanelekileyo wokuwuthatha kanye ngosuku.Emva kokuyithatha iintsuku ezi-5 ezilandelelanayo, uxinzelelo lwegazi lwesigulane luya kuncipha ngokucacileyo.Omnye umsebenzi weli yeza kukunceda izigulana zikhuphe i-uric acid eninzi kumchamo.Ngoko ke, ngokubanzi, kufanelekile kwaye kukhuselekile ukuthatha eli yeza xa izigulane ezinoxinzelelo lwegazi zikhatshwa yimpawu zokwanda kwe-uric acid.Kwiminyaka yakutshanje, kwiklinikhi, i-losartan idityaniswe ne-diuretic hydrochloride yenziwa ithebhulethi edibeneyo ebizwa ngokuba yi-Hyzaar.2. I-Valsartan: Isiphumo seli chiza le-antihypertensive sikhawuleza kakhulu, kwaye ixesha lokuqala lincinci, kwaye ngokubanzi izigulane kufuneka zilithathe kanye ngosuku.3. Irbesartan: Igama lentengiso yeli chiza le-sartan antihypertensive yi-Ambovir Ngokubanzi, izigulane kufuneka zithathe ithebhulethi enye ngosuku.Ukuthetha ngokuthelekisayo, ukufunxa ngomlomo kulungile, kwaye umphumo awuchatshazelwa kukutya.4. I-Telmisartan, lichiza elisebenza ixesha elide le-antihypertensive.Isetyenziswe kuphela kwimisebenzi yeklinikhi kwiminyaka yamuva.Inefuthe elihle kunye neziphumo ezibi eziphantsi.Ithathwa kanye ngosuku.