(2R,3S)-1,2-Epoxy-3-(Boc-Amino)-4-Phenylbutane CAS 98760-08-8 Atazanavir Intermediate High Purity

Inkcazelo emfutshane:

Igama: (2R,3S)-1,2-Epoxy-3-(Boc-Amino)-4-Phenylbutane

(2R,3S)-3-(tert-Boc)amino-1,2-epoxy-4-phenylbutane

CAS: 98760-08-8

Imbonakalo: Mhlophe ukuya kuMhlophe-Mhlophe wePowder

Ubunyulu: ≥99.0% (HPLC)

Umbindi we-Atazanavir (CAS 198904-31-3) HIV-1 Protease Inhibitor

Umgangatho ophezulu, iMveliso yoRhwebo

Inquiry: alvin@ruifuchem.com

Thumela i-imeyile kuthi

Iinkcukacha zeMveliso

Iimveliso ezinxulumeneyo

Iithegi zeMveliso

Inkcazo:

Ubonelelo loMvelisi oluNxulumeneyo ne-Atazanavir
I-Moc-L-Tert-Leucine CAS 162537-11-3
4-(2-Pyridyl)benzaldehyde CAS 127406-56-8
(2S,3S)-1,2-Epoxy-3-(Boc-Amino)-4-Phenylbutane CAS 98737-29-2
(2R,3S)-1,2-Epoxy-3-(Boc-Amino)-4-Phenylbutane CAS 98760-08-8
tert-Butyl 2-(4-(pyridin-2-yl)benzyl)hydrazinecarboxylate CAS 198904-85-7
Atazanavir CAS 198904-31-3
Atazanavir Sulfate CAS 229975-97-7
Umgangatho ophezulu, iMveliso yoRhwebo

Iipropati zeMichiza:

Igama leMchiza	(2R,3S)-1,2-Epoxy-3-(Boc-Amino)-4-Phenylbutane
Izithethantonye	(2R,3S)-3-(tert-Boc)amino-1,2-epoxy-4-phenylbutane;(2R,3S)-3-(tert-Butoxycarbonyl)amino-1,2-epoxy-4-phenylbutane;I-Atazanavir ePhakathi;Ukungacoceki kwe-Atazanavir C;I-threo-N-Boc-L-phenylalanine epoxide
Inombolo yeCAS	98760-08-8
Inombolo yeCAT	RF-PI288
Ubume beStokhwe	Kwi-Stock, iMveliso yoMveliso ukuya kwiiToni
Ifomula yeemolekyuli	C15H21NO3
Ubunzima beMolekyuli	263.34
Imeko yokuthumela ngenqanawa	Phantsi koBubushushu be-Ambient
Uphawu	Ruifu Chemical

Iinkcukacha:

Into	Iinkcukacha
Imbonakalo	Mhlophe ukuya kuMhlophe-Mhlophe wePowder
Ukuchongwa	Ukuchongwa kuqinisekiswe yi-HPLC RT
Ukunyibilika	Inyibilika kwiMethanol
Ukujikeleziswa okuthe ngqo	-10°~ -20°
Amanzi (KF)	≤0.50%
Intsalela kwi-Ignition	≤0.20%
Izinto ezinxulumeneyo
Ukungcola (RRT0.97)	≤0.30%
Nakuphi na Ukungacoceki Okukodwa	≤0.30%
Ukungcola ngokupheleleyo	≤1.0%
Iintsimbi ezinzima	≤20ppm
Ubunyulu / Indlela yokuHlalutya	≥99.0% (HPLC)
Ucoceko lwe-Enantiomeric	≤0.30%
Umgangatho woVavanyo	Umgangatho woShishino
Ukusetyenziswa	Umbindi we-Atazanavir (CAS 198904-31-3) HIV-1 Protease Inhibitor

Ukupakishwa kunye noGcino:

Iphakheji: Ibhotile, ingxowa yefoyile yeAluminiyam, Igubu lekhadibhodi, 25kg/Igubu, okanye ngokwemfuno yomthengi.

Imeko yoGcino:Gcina kwizikhongozeli ezivaliweyo kwindawo epholileyo neyomileyo;Khusela ekukhanyeni, ukufuma kunye nokuhlaselwa zizinambuzane.

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FAQ:

Isicelo:

I-Shanghai Ruifu Chemical Co., Ltd. ngumenzi ohamba phambili kunye nomthengisi we (2R,3S) -1,2-Epoxy-3- (Boc-Amino) -4-Phenylbutane (CAS 98760-08-8) kunye nomgangatho ophezulu, i-intermediate ye-Atazanavir (CAS 198904-31-3) kunye ne-Atazanavir Sulfate (CAS 229975-97-7).I-Atazanavir yinoveli ye-azapeptide HIV protease inhibitor (PI).

I-Atazanavir sisithinteli sohlobo loku-1 lwentsholongwane yokhuselo lomzimba (HIV-1) protease, i-enzyme eyimfuneko ekusetyenzweni kwe-Gag kunye ne-Gag-Pol polyproteins ibe yiprotein yolwakhiwo kunye ne-enzymatic efunekayo kuphindaphindo lwentsholongwane.Ine-pharmacophore motif efanayo kwezinye ii-HIV protease inhibitors ezintandathu ezithengiswe ngokubanzi, uninzi lwazo zisekelwe kwitemplate ye-hydroxyethylamine.Ngokukodwa, ine-aza-peptide motif kodwa igcina izinto ezininzi ezifanayo ze-pharmacophore kuquka i-lipophilic moieties ekucingelwa ukuba ibophelela kwizithuba ze-S2, S1, S′1, kunye ne-S′2.