(2S,3S)-1,2-Epoxy-3-(Boc-Amino)-4-Phenylbutane CAS 98737-29-2 Atazanavir Intermediate High Purity
Ubonelelo loMvelisi oluNxulumeneyo ne-Atazanavir
I-Moc-L-Tert-Leucine CAS 162537-11-3
4-(2-Pyridyl)benzaldehyde CAS 127406-56-8
(2S,3S)-1,2-Epoxy-3-(Boc-Amino)-4-Phenylbutane CAS 98737-29-2
(2R,3S)-1,2-Epoxy-3-(Boc-Amino)-4-Phenylbutane CAS 98760-08-8
tert-Butyl 2-(4-(pyridin-2-yl)benzyl)hydrazinecarboxylate CAS 198904-85-7
Atazanavir CAS 198904-31-3
Atazanavir Sulfate CAS 229975-97-7
Igama leMchiza | (2S,3S)-1,2-Epoxy-3-(Boc-Amino)-4-Phenylbutane |
Izithethantonye | (2S,3S)-3-(Boc-Amino)-1,2-Epoxy-4-Phenylbutane;(2S,3S)-3-(tert-Butoxycarbonylamino)-1,2-epoxy-4-phenylbutane;I-Darunavir ePhakathi |
Inombolo yeCAS | 98737-29-2 |
Inombolo yeCAT | RF-PI286 |
Ubume beStokhwe | Kwi-Stock, iMveliso yoMveliso ukuya kwiiToni |
Ifomula yeemolekyuli | C15H21NO3 |
Ubunzima beMolekyuli | 263.33 |
Ukunyibilika | Ayinyibilikiyo emanzini.Inyibilika kwiMethanol, iChloroform |
Imeko yokuthumela ngenqanawa | Ithunyelwe Ngaphantsi Kweqondo Lobushushu Le-Ambient |
Uphawu | Ruifu Chemical |
Into | Iinkcukacha |
Imbonakalo | Mhlophe ukuya kuMhlophe oMhlophe wePowder |
Ukuchongwa (HPLC) | Ukuchongwa kungqinwe yi-HPLC |
Indawo yokunyibilika | 123.0 ~ 128.0℃ |
Ukufuma (KF) | ≤0.50% |
Intsalela kwi-Ignition | ≤0.20% |
Ubunyulu / Indlela yokuHlalutya | ≥99.0% (HPLC) |
I-Chlorohydrin (HPLC) | ≤0.20% |
I-Chloromethyl Ketone | ≤0.10% |
Okunye Ukungcola Okukodwa | ≤0.20% |
Ukungcola ngokupheleleyo | ≤1.0% |
Ukungacoceki kweChiral | ≤0.30% |
Iintsimbi ezinzima | ≤20ppm |
Umgangatho woVavanyo | Umgangatho woShishino |
Ukusetyenziswa | Umbindi weDarunavir (CAS 206361-99-1) HIV-1 Protease Inhibitor |
Iphakheji: Ibhotile, ingxowa yefoyile yeAluminiyam, Igubu lekhadibhodi, 25kg/Igubu, okanye ngokwemfuno yomthengi.
Imeko yoGcino:Gcina kwizikhongozeli ezivaliweyo kwindawo epholileyo neyomileyo;Khusela ekukhanyeni, ukufuma kunye nokuhlaselwa zizinambuzane.
I-Shanghai Ruifu Chemical Co., Ltd. ngumenzi ohamba phambili kunye nomthengisi we (2S,3S) -1,2-Epoxy-3- (Boc-Amino) -4-Phenylbutane (CAS: 98737-29-2) kunye nomgangatho ophezulu. , i-intermediate ngokuqhelekileyo kwi-synthesis ye-Atazanavir (CAS 198904-31-3) kunye ne-Atazanavir Sulfate (CAS 229975-97-7).
I-Atazanavir yi-HIV-1 protease inhibitor enamandla kakhulu.Ibonise ukuba inamandla ngokubanzi kunentlanu evunyiweyo ngoku ye-HIV-1 Prt inhibitors.I-Atazanavir (BMS-232632) ithintele ukuqhekeka kwe-proteolytic ye-viral gag precursor p55 polyprotein ngendlela exhomekeke kwithamo, kunye ne-EC 50 emalunga nama-47 nM.Kwakhona ukukhetha kakhulu kwi-HIV-1 Prt kwaye ibonisa i-cytotoxicity kuphela ekugxininiseni i-6,500- ukuya kuma-23,000 ngokuphindwe ngaphezulu kunoko kufunekayo kumsebenzi ochasene ne-HIV.I-Atazanavir (BMS-232632) inokuba sisithinteli se-HIV-1 esisebenzayo esinokuthi sisetyenziswe kwiindidi ezahlukeneyo zendibaniselwano yamachiza.