I-3-HydroxyCephem (3-OH) CAS 54639-48-4 Ubunyulu ≥99.0% (HPLC) Cephalosporin Ceftaroline Fosamil Intermediate
Ubonelelo lwabavelisi, ubunyulu obuphezulu, iMveliso yoRhwebo
Igama leMchiza: 3-HydroxyCephem (3-OH)
CAS: 54639-48-4
Igama leMchiza | (6R,7R) -3-Hydroxy-8-oxo-7-[(phenylacetyl) amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid diphenyl methyl ester |
Izithethantonye | 3-HydroxyCephem;3-OH;GHYH |
Inombolo yeCAS | 54639-48-4 |
Inombolo yeCAT | RF-PI560 |
Ubume beStokhwe | Kwi-Stock, iMveliso yoMveliso ukuya kwiiToni |
Ifomula yeemolekyuli | I-C28H24N2O5S |
Ubunzima beMolekyuli | 500.57 |
Uphawu | Ruifu Chemical |
Into | Iinkcukacha |
Imbonakalo | Umgubo oMhlophe okanye oMhlophe |
Ukuchongwa | IR, NMR Positive |
Ubunyulu / Indlela yokuHlalutya | ≥99.0% (HPLC) |
Ukufuma (KF) | ≤0.50% |
Ukungacoceki Okukodwa | ≤0.50% |
Ukungcola ngokupheleleyo | ≤1.0% |
Izinyibilikisi ezishiyekileyo | ≤1.0% |
Penicillin Potassium Residual | ≤1ppm |
Umgangatho woVavanyo | Umgangatho woShishino |
Ukusetyenziswa | Iphakathi kwiCephalosporins-derived inhibitors, iCeftaroline Fosamil |
Iphakheji: Ibhotile, ingxowa yefoyile yeAluminiyam, 25kg/Igubu lekhadibhodi, okanye ngokwemfuno yomthengi.
Imeko yoGcino:Gcina kwizikhongozeli ezivaliweyo kwindawo epholileyo neyomileyo;Khusela ukukhanya kunye nokufuma.
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I-3-Hydroxycephem (3-OH) (i-CAS: 54639-48-4), ikhonkco eliphambili leCephalosporin, lisetyenziselwa ukulungiselela i-Cephalosporin-derived inhibitors.Isenokusetyenziswa ukwenza i-Ceftaroline Fosamil eyi-antibiotic ye-Cephalosporin.I-Ceftaroline, i-metabolite esebenzayo ye-prodrug i-Ceftaroline Fosamil (i-Zinforo, i-Teflaro), isizukulwana esihambele phambili, i-Cephalosporin yomzali kunye nomsebenzi obanzi we-antibacterial in vitro ngokuchasene ne-Gram-positive bacteria, kuquka i-methicillin-resistant Staphylococcus aureus (MRSA) kunye ne-multidrug resistant. I-Streptococcus pneumoniae kunye ne-Gram-negative bacteria, kuquka i-Haemophilus influenzae kunye ne-Moraxella catarrhalis, kodwa kungekhona i-Pseudomonas aeruginosa.
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