I-3-Methyl-6-Nitroindazole CAS 6494-19-5 Ubunyulu > 98.0% (HPLC)

Inkcazelo emfutshane:

Igama leKhemikhali: 3-Methyl-6-Nitroindazole

CAS: 6494-19-5

Ubunyulu: >98.0% (HPLC)

Mthubi oKhanyayo ukuya kuMthubi oMnyama ukuya kwiPowder eBrown ukuya kwiCrystal

Umgangatho ophezulu, iMveliso yoRhwebo

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Inkcazo:

Shanghai Ruifu Chemical Co., Ltd. is the leading supplier of 3-Methyl-6-Nitroindazole (CAS: 6494-19-5) with high quality. We can provide COA, worldwide delivery, small and bulk quantities available. If you are interested in this product, please send detailed information includes CAS number, product name, quantity to us. Please contact: alvin@ruifuchem.com

Iipropati zeMichiza:

Igama leMchiza	3-Methyl-6-Nitroindazole
Izithethantonye	3-Methyl-6-Nitro-1H-Indozole;6-Nitro-3-Methylindazole
Inombolo yeCAS	6494-19-5
Inombolo yeCAT	RF2682
Ubume beStokhwe	Kwi-Stock, iMveliso yoMveliso ukuya kwiiToni
Ifomula yeemolekyuli	C8H7N3O2
Ubunzima beMolekyuli	177.16
Indawo yokunyibilika	184.0 ukuba 188.0℃
Indawo yokubilisa	384.9±22.0℃
Ukuxinana	1.437
Ukunyibilika	I-Chloroform (Kancinci), iMethanol (Kancinci)
Uphawu	Ruifu Chemical

Iinkcukacha:

Into	Iinkcukacha
Imbonakalo	Mthubi oKhanyayo ukuya kuMthubi oMnyama ukuya kwiPowder eBrown ukuya kwiCrystal
Ubunyulu / Indlela yokuHlalutya	>98.0% (HPLC)
Indawo yokunyibilika	184.0 ukuba 188.0℃
Ilahleko ekomisweni	<1.00%
Ukungcola ngokupheleleyo	<2.00%
I-Infrared Spectrum	Iyahambelana neSakhiwo
Proton NMR Spectrum	Iyahambelana neSakhiwo
Umgangatho woVavanyo	Umgangatho woShishino
Ukusetyenziswa	Phakathi kwezamayeza;Pazopanib Hydrochloride Intermediate

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Isicelo:

I-3-Methyl-6-Nitroindazole (i-CAS: i-6494-19-5) isetyenziswe njenge-Pharmaceutical Intermediate.Ingasetyenziselwa njengendawo ephakathi yePazopanib Hydrochloride (CAS: 635702-64-6).I-Pazopanib Hydrochloride iphandiwe kwaye yaphuhliswa yi-GlaxoSmithKline, yinoveli yomlomo we-vascular generation inhibitor enokuphazamisa ukusinda kwethumba elinenkani kunye nokukhula kwemithambo yegazi emitsha efunekayo.Ukujolisa i-vascular endothelial growth factor receptor (VEGFR), isebenza ngokuthintela i-angiogenesis ye-tumor blood supply.Ifanelekile kwi-renal cell carcinoma ye-renal cell (ukufunyanwa kweeseli zomhlaza kwii-renal tubules), i-soft tissue sarcoma (STS), umhlaza we-ovarian we-epithelial kunye nonyango olungelulo oluncinci lwe-cell lung (NSCLC).I-US Food and Drug Administration (FDA) yamkelwe ngo-Okthobha 19, 2009 ukuba iPazopanib Hydrochloride (igama lorhwebo iVotrient) idweliswe, iyeza lesithandathu elivunyiweyo lonyango lomhlaza wezintso ukusukela ngo-2005.