I-Darunavir Intermediate CAS 102123-74-0 Ubunyulu ≥98.0% (HPLC)
Ubonelelo loMvelisi kwiiMveliso eziNxulumene neDarunavir:
I-Darunavir CAS 206361-99-1
I-Darunavir Ethanolate CAS 635728-49-3
(2S,3S)-1,2-Epoxy-3-(Boc-Amino)-4-Phenylbutane CAS 98737-29-2
(2R,3S)-1,2-Epoxy-3-(Boc-Amino)-4-Phenylbutane CAS 98760-08-8
(3S)-3-(tert-Butoxycarbonyl)amino-1-Chloro-4-Phenyl-2-Butanone CAS 102123-74-0
| Igama leMchiza | (3S)-3-(tert-Butoxycarbonyl)amino-1-Chloro-4-Phenyl-2-Butanone |
| Izithethantonye | (S)-tert-Butyl (4-Chloro-3-oxo-1-Phenylbutan-2-yl)Carbamate |
| Inombolo yeCAS | 102123-74-0 |
| Inombolo yeCAT | RF-PI287 |
| Ubume beStokhwe | Kwi-Stock, iMveliso yoMveliso ukuya kwiiToni |
| Ifomula yeemolekyuli | I-C15H20ClNO3 |
| Ubunzima beMolekyuli | 297.78 |
| Imeko yokuthumela ngenqanawa | Ithunyelwe Ngaphantsi Kweqondo Lobushushu Le-Ambient |
| Uphawu | Ruifu Chemical |
| Into | Iinkcukacha |
| Imbonakalo | Mhlophe ukuya kuMhlophe-Mhlophe wePowder |
| Ukuchongwa (HPLC) | Ukuchongwa kungqinwe yi-HPLC |
| Ilahleko ekomisweni | ≤0.50% |
| Ukufuma (KF) | ≤0.50% |
| Indawo yokunyibilika | 104.0 ~ 107.0℃ |
| Intsalela kwi-Ignition | ≤0.20% |
| Ukujikeleziswa okuthe ngqo | -48.0 ° ~ -42.0 ° |
| Ubunyulu / Indlela yokuHlalutya | ≥98.0% (HPLC) |
| Umgangatho woVavanyo | Umgangatho woShishino |
| Ukusetyenziswa | Umbindi weDarunavir (CAS 206361-99-1) HIV-1 Protease Inhibitor |
Iphakheji: Ibhotile, ingxowa yefoyile yeAluminiyam, Igubu lekhadibhodi, 25kg/Igubu, okanye ngokwemfuno yomthengi.
Imeko yoGcino:Gcina kwizikhongozeli ezivaliweyo kwindawo epholileyo neyomileyo;Khusela ekukhanyeni, ukufuma kunye nokuhlaselwa zizinambuzane.
I-Shanghai Ruifu Chemical Co., Ltd. ngumenzi ohamba phambili kunye nomthengisi we (3S) -3- (tert-Butoxycarbonyl) amino-1-Chloro-4-Phenyl-2-Butanone (CAS: 102123-74-0) kunye umgangatho, ophakathi ngokuqhelekileyo kwi-synthesis yeDarunavir (CAS 206361-99-1) kunye neDarunavir Ethanolate (CAS 635728-49-3).
I-Darunavir (i-CAS 206361-99-1) (i-TMC114) sisizukulwana sesibini se-nonpeptidic HIV protease inhibitor, esetyenziselwa ukunyanga i-AIDS kunye nosulelo lwe-HIV, ngokwesakhiwo esifana ne-amprenavir.I-Antiviral.Ngenxa yokuvela kokunganyangeki kweyeza le-Antiviral xa lisetyenziswa lodwa, lilawulwa ngokudibeneyo nezinye ii-Anti-HIV.I-Darunavir yi-oral-bioavailable non-peptidic inhibitor ye-human immunodeficiency virus type 1 (HIV-1) protease enqanda ngokukhethayo i-HIV-1 protease enzyme ebangela ukuqhekeka kwe-gag kunye ne-gag-pol poly-protein ethintela ukukhula kwee-virions kwaye ikwanqanda intsholongwane. Ukunciphisa i-HIV-1 protease icinezela umsebenzi weproteolytic kunye nokuphindaphinda okulandelayo kwe-HIV-1.
