4-[(1-Pyrrolidinylsulfonyl)methyl]aniline CAS 334981-10-1 Ubunyulu>99.0% (HPLC) I-Almotriptan Aniline Precursor Factory

Inkcazelo emfutshane:

Igama: 4-[(1-Pyrrolidinylsulfonyl)methyl]aniline

CAS: 334981-10-1

Ubunyulu: >99.0% (HPLC)

Imbonakalo: Mhlophe ukuya kuFaka umgubo weCrystalline oMthubi

Umbindi we-Almotriptan Malate (CAS: 181183-52-8)

Umgangatho ophezulu, iMveliso yoRhwebo

E-Mail: alvin@ruifuchem.com


Iinkcukacha zeMveliso

Iimveliso ezinxulumeneyo

Iithegi zeMveliso

Inkcazo:

Iipropati zeMichiza:

Igama leMchiza 4-[(1-Pyrrolidinylsulfonyl)methyl]aniline
Izithethantonye 1-[(4-Aminobenzyl)sulfonyl]pyrrolidine;Almotriptan Aniline Precursor
Inombolo yeCAS 334981-10-1
Inombolo yeCAT RF-PI1948
Ubume beStokhwe Kwi-Stock, iMveliso yoMveliso ukuya kwiiToni
Ifomula yeemolekyuli I-C11H16N2O2S
Ubunzima beMolekyuli 240.32
Indawo yokunyibilika 170.0 ukuya 176.0℃
Ukuxinana 1.31
Ukunyibilika Inyibilika kancinane kwiToluene
Uphawu Ruifu Chemical

Iinkcukacha:

Into Iinkcukacha
Imbonakalo Umgubo weCrystalline oMthubi ukuya kuMthubi
Ubunyulu / Indlela yokuHlalutya >99.0% (HPLC)
Ilahleko ekomisweni <0.50%
Intsalela kwi-Ignition <0.50%
Ukungahlambuluki Okukodwa okuphezulu <0.50%
Ukungcola ngokupheleleyo <1.00%
Iintsimbi ezinzima <20ppm
I-Infrared Spectrum Iyahambelana noLwakhiwo
NMR Iyahambelana noLwakhiwo
Umgangatho woVavanyo Umgangatho woShishino
Ukusetyenziswa Almotriptan Aniline Precursor

Ukupakishwa kunye noGcino:

Iphakheji: Ibhotile, ingxowa yefoyile yeAluminiyam, 25kg/Igubu lekhadibhodi, okanye ngokwemfuno yomthengi

Imeko yoGcino:Gcina kwizikhongozeli ezivaliweyo kwindawo epholileyo neyomileyo;Khusela ukukhanya kunye nokufuma

Izinto eziluncedo:

1

FAQ:

Isicelo:

I-4-[(1-Pyrrolidinylsulfonyl) methyl]aniline (CAS: 334981-10-1) iphakathi ekulungiseleleni i-Almotriptan Malate (CAS: 181183-52-8), i-Almotriptan Aniline Precursor.I-Almotriptan Malate luhlobo lwechiza le-triptan elinokusetyenziswa kunyango lwentloko eqaqambayo.I-Almotriptan iyinxalenye yeziyobisi ezikhethiweyo ze-serotonin receptor agonists.I-Almotriptan inobudlelwane obuphezulu kunye obucacileyo be-serotonin i-5-HT i-receptors, ngakumbi ikhokelela kwi-vascoconstriction ye-brain blood vessel kunye nokuchaphazela ukwabiwa kwakhona kwegazi.Ezi ziphumo zimisa iimpawu zentlungu ekuthunyelweni kwengqondo, kwaye zicinezela ngakumbi ukukhululwa kwezinto ezithile zendalo ezibangela intlungu, isicaphucaphu kunye nezinye iimpawu ze-migraine.Nangona kunjalo, i-Almotriptan ayikuthinteli ukuhlaselwa kwe-migraine.I-Almotriptan, ithengiswe ngo-2000, ineyona ndawo iphezulu ye-oralbioavailability kuzo zonke iitriptan.I-Almotriptan i-metabolized zombini i-MAO-A kunye ne-CYP3A4, ngoko ke ineprofayili yeziphumo ezithandekayo xa ithelekiswa ne-Sumatriptan.

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