4-Amino-2-Methylbenzoic Acid CAS 2486-75-1 Tolvaptan Intermediate Factory
Ubonelelo loMvelisi, uMgangatho oPhezulu, iMveliso yoRhwebo
I-Tolvaptan kunye nabaPhakathi abaNxulumeneyo:
Tolvaptan CAS 150683-30-0
7-Chloro-1,2,3,4-tetrahydrobenzo[b]azepin-5-enye CAS 160129-45-3
o-Toluoyl Chloride CAS 933-88-0
I-4-Amino-2-Methylbenzoic Acid CAS 2486-75-1
I-2-Methyl-4-Nitrobenzoic Acid CAS 1975-51-5
| Igama leMchiza | I-4-Amino-2-Methylbenzoic Acid |
| Izithethantonye | I-4-Amino-o-toluic Acid;Tolvaptan Intermediate N-2 |
| Inombolo yeCAS | 2486-75-1 |
| Inombolo yeCAT | RF-PI394 |
| Ubume beStokhwe | Kwi-Stock, iMveliso yoMveliso ukuya kwiiToni |
| Ifomula yeemolekyuli | C8H9NO2 |
| Ubunzima beMolekyuli | 151.17 |
| Ukunyibilika | Inyibilika kwiMethanol |
| Uphawu | Ruifu Chemical |
| Into | Iinkcukacha |
| Imbonakalo | Umgubo weCrystal omhlophe okanye otyheli |
| Indlela yokuhlanjululwa / yoHlalutya | ≥99.0% (HPLC) |
| Ukufuma | ≤0.50% (KF) |
| Indawo yokunyibilika | 161.0 ~ 168.0℃ |
| Intsalela kwi-Ignition | ≤0.50% |
| Ukungacoceki Okukodwa | ≤0.50% |
| Ukungcola ngokupheleleyo | ≤1.0% |
| Umgangatho woVavanyo | Umgangatho woShishino |
| Ukusetyenziswa | Phakathi kweTolvaptan (CAS 150683-30-0), unyango lwe-Hyponatremia |
Iphakheji: Ibhotile, ingxowa yefoyile yeAluminiyam, 25kg/Igubu lekhadibhodi, okanye ngokwemfuno yomthengi.
Imeko yoGcino:Gcina kwizikhongozeli ezivaliweyo kwindawo epholileyo neyomileyo;Khusela ukukhanya kunye nokufuma.
I-4-Amino-2-Methylbenzoic Acid (i-CAS 2486-75-1) isetyenziswe njengendawo ephakathi kwi-synthesis ye-pharmaceutical intermediates kunye ne-Active Pharmaceutical Ingredient (API) synthesis.I-4-Amino-2-Methylbenzoic Acid iphakathi kweTolvaptan (CAS 150683-30-0).I-Tolvaptan ngumchasi we-vasopressin okhethiweyo womlomo ophuhliswe ngu-Otsuka kunyango lwe-hyponatremia, kwaye i-non-peptide ekhethiweyo ye-antidiuretic hormone receptor antagonist.Ichiza linokunyusa ukuxinwa kwee-ion zesodium kwiplasma, kwaye incede ukuphuma kwamanzi amaninzi kumchamo.Ichiza linokuphucula amandla ezintso ekujonganeni namanzi, kwaye linciphise kakhulu ubunzima kunye ne-edema yezigulana ngelixa lingakhatshwa kukonyuka kwe-electrolyte excretion, ngaphandle kokutshabalalisa ibhalansi ye-electrolyte yegazi.Ichiza lingasetyenziselwa ukunyanga i-hyponatremia ebangelwa kukungaphumeleli kwentliziyo, izifo ezahlukeneyo ze-edema, i-cirrhosis kunye ne-antidiuretic hormone deficiency syndrome.
![7-Chloro-1,2,3,4-tetrahydrobenzo[b]azepin-5-enye CAS 160129-45-3 Tolvaptan Intermediate](https://www.ruifuchemical.com/uploads/7-Chloro-1234-tetrahydrobenzobazepin-5-one-CAS-160129-45-3-300x300.jpg)
