I-4-Aminosalicylic Acid CAS 65-49-6 Ubunyulu > 99.0% (HPLC) (T) Factory

Inkcazelo emfutshane:

Igama leKhemikhali: 4-Aminosalicylic Acid

Izithethantonye: 4-Amino-2-Hydroxybenzoic Acid;4-ASA;I-PAS

CAS: 65-49-6

Ubunyulu: >99.0% (HPLC) (T)

Imbonakalo: Umgubo oMhlophe-Obumhlophe okanye oMthubi kancinane

Umgangatho we-USP, iMveliso yoRhwebo

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Inkcazo:

I-Shanghai Ruifu Chemical Co., Ltd. ngumenzi ohamba phambili kunye nomthengisi we-4-Aminosalicylic Acid (CAS: 65-49-6) enomgangatho ophezulu.Sinokubonelela nge-COA, ukuhanjiswa kwehlabathi jikelele, ubuninzi obuncinci kunye nobuninzi obukhoyo.Ukuba unomdla kule mveliso, nceda uthumele ulwazi oluneenkcukacha lubandakanya inombolo ye-CAS, igama lemveliso, ubuninzi kuthi.Please contact: alvin@ruifuchem.com

Iipropati zeMichiza:

Igama leMchiza	I-4-Aminosalicylic Acid
Izithethantonye	I-4-Amino-2-Hydroxybenzoic Acid;I-4-Amino-Salicylic Acid;4-ASA;I-PAS;I-Para-Aminosalicylic Acid;p-Aminosalicylic Acid;I-Aminosalicylic Acid;Amino-PAS;4-Aminosalicylate
Ukungcola	Mesalazine EP Ukungcola E
Inombolo yeCAS	65-49-6
Inombolo yeCAT	RF2746
Ubume beStokhwe	KwiSitokhwe, Umthamo weMveliso iiToni ezingama-30 ngenyanga
Ifomula yeemolekyuli	C7H7NO3
Ubunzima beMolekyuli	153.14
Indawo yokunyibilika	135.0~145.0℃(lit.)
Inovakalelo	Hygroscopic.UkuKhanya okungevayo, ukungeva komoya
Ukunyibilika kwiMethanol	Phantse Ukungafihli
Uphawu	Ruifu Chemical

Iinkcukacha:

Into	Iinkcukacha
Imbonakalo	Umgubo oMhlophe okanye oMthubi kancinane
Ukuchongwa	Qalisa Ukusabela Okulungileyo
Ukucaca kunye nombala wesisombululo	Iyahambelana
Ubunyulu / Indlela yokuHlalutya	>99.0% (HPLC)
Ubunyulu / Indlela yokuHlalutya	98.5 ~ 101.5% (Titration by NaOH)
Indawo yokunyibilika	135.0 ~ 145.0℃
Ilahleko ekomisweni	<0.50%
Intsalela kwi-Ignition	<0.20%
Ikloridi (Cl)	<0.042%
Iintsimbi ezinzima	<30ppm
M-Aminophenol Umxholo	<0.25% (HPLC)
I-Hydrogen Sulfide, i-Sulfur Dioxide kunye ne-Amyl Alcohol	Iyahambelana
Ukungcola ngokupheleleyo	<1.00%
pH	3.0~3.7
I-Infrared Spectrum	Iyahambelana neSakhiwo
Proton NMR Spectrum	Iyahambelana neSakhiwo
Umgangatho woVavanyo	Le Mveliso ngokuHlolwa ngokweSivumelwano soMgangatho we-USP30
Ukusetyenziswa	AbaPhakathi bamayeza

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Isicelo:

I-4-Aminosalicylic Acid (4-ASA) (i-CAS: 65-49-6), i-aminobenzoic acid ene-salicylic acid ethatyathwe liqela le-amino kwindawo ye-4, yenye yeziyobisi eziseleyo ezifumanekayo zokunyanga iziyobisi ezixhasiweyo ( XDR) isifo sephepha.Yi-agent ye-antitubercular ehlala ilawulwa ngokubambisana ne-Isoniazid.I-4-Aminosalicylic Acid ibonisa imisebenzi yokuchasa, i-antioxidative, kunye ne-antibacterial;isetyenziswe ngokweklinikhi ukunyanga isifo sofuba (IBD), isifo sikaCrohn, kunye ne-colitis, njengoko isebenza ngokuyinhloko kwikholoni.Ngokuqhelekileyo ithathwa ngomlomo.I-4-Aminosalicylic Acid isetyenziswa ngokuchasene neMycobacterium njengonyango lwesifo sephepha;inqanda umsebenzi we-dihydrofolate reductase (DHFR) njenge-antimetabolite.I-4-Aminosalicylic Acid, ichiza le-antituberculosis, ngumzekelo osebenzayo we-pharmaceutical ingredient ukufunda ityuwa kunye nokwakheka kwe-cocrystal kwi-molecule ye-hydrogen-bonding functionality kunye ne-carboxylic acid, i-amine kunye namaqela e-phenol.I-antibacterial ekwazi ukuthintela ukukhula kwe-Mycobacterium tuberculosis.I-4-Aminosalicylic Acid ingasetyenziselwa ukuhlanganiswa kwe: I-Azo derivatives ye-4-ASA eneziphumo ezichasayo;I-Ammonium 4-aminosalicylate i-polymorphs yetyuwa esetyenziswa njengezithako zamachiza;I-Salicylic acid-triazole analogs ezisetyenziswa njenge-quorum sensing inhibitors ngokuchasene nePseudomonas aeruginosa.