Olaparib Intermediate CAS 763114-26-7 Ubunyulu ≥98.5% Factory
Ukucoceka okuphezulu, iMveliso yoRhwebo
I-Olaparib kunye nabaPhakathi abaNxulumeneyo:
Olaparib CAS 763113-22-0
2-Fluoro-5-Formylbenzonitrile CAS 218301-22-5
I-2-Fluoro-5-((4-oxo-3,4-dihydrophthalazin-1-yl)methyl)benzoic acid CAS 763114-26-7
1-(Cyclopropylcarbonyl)piperazine Hydrochloride CAS 1021298-67-8
3-Oxo-1,3-Dihydroisobenzofuran-1-Ylphosphonic Acid CAS 61260-15-9
| Igama leMchiza | 2-Fluoro-5-((4-oxo-3,4-dihydrophthalazin-1-yl)methyl)benzoic acid |
| Izithethantonye | 2-Fluoro-5-[(4-oxo-3H-phthalazin-1-yl)methyl]benzoic acid |
| Inombolo yeCAS | 763114-26-7 |
| Inombolo yeCAT | RF-PI450 |
| Ubume beStokhwe | Kwi-Stock, iMveliso yoMveliso ukuya kwiiToni |
| Ifomula yeemolekyuli | I-C16H11FN2O3 |
| Ubunzima beMolekyuli | 298.27 |
| Uphawu | Ruifu Chemical |
| Into | Iinkcukacha |
| Imbonakalo | Mthubi ukuya kumgubo oMhlophe |
| Isivavanyi | ≥98.5% |
| Ukufuma (KF) | ≤0.50% |
| Ukungcola ngokupheleleyo | ≤1.5% |
| Umgangatho woVavanyo | Umgangatho woShishino |
| Ukusetyenziswa | Umbindi we-Olaparib (CAS: 763113-22-0) |
Iphakheji: Ibhotile, ingxowa yefoyile yeAluminiyam, Igubu lekhadibhodi, 25kg/Igubu, okanye ngokwemfuno yomthengi.
Imeko yoGcino:Gcina kwizikhongozeli ezivaliweyo kwindawo epholileyo neyomileyo;Khusela ukukhanya kunye nokufuma.
I-2-Fluoro-5- ((4-oxo-3,4-dihydrophthalazin-1-yl) methyl) i-benzoic acid (i-CAS: 763114-26-7) yindawo ephakathi esetyenziswe kwi-synthesis ye-Olaparib (CAS: 763113-22) -0).I-Olaparib, ethengiswe ngu-AstraZeneca phantsi kwegama le-brand Lynparza, yamkelwa e-USA ngoDisemba ka-2014 njengonyango olujoliswe kuyo, lwe-arhente enye yonyango lwe-germline ye-BRCA-mediated advanced ovarian cancer. , isebenza njenge-poly ADP ribose polymerase inhibitor kwaye yamkelwe ngokukodwa izigulane ezifumene unyango lwechemotherapy ezintathu nangaphezulu.Kulingo lweklinikhi, ichiza landisa ixesha elide lokusinda kwizigulane ezinomhlaza we-ovarian we-serous ovarian-sensitive yeplatinam.I-Olaparib ikwangoku ikwizigaba ezahlukeneyo zophando kunyango lwebele, i-gastric, i-prostate, i-pancreatic kunye nomhlaza wemiphunga weseli ongemncinci.
