4-Chloro-3-(Trifluoromethyl)phenyl Isocyanate CAS 327-78-6 Ucoceko ≥99.0% Sorafenib Tosylate Intermediate Factory
Ubonelelo ngezoRhwebo i-Sorafenib Tosylate kunye neziPhakathi eziNxulumeneyo:
I-Sorafenib Tosylate CAS: 475207-59-1
Sorafenib CAS: 284461-73-0
I-4-Chloro-N-Methyl-2-Pyridinecarboxamide CAS: 220000-87-3
I-4-(4-Aminophenoxy)-N-Methylpicolinamide CAS: 284462-37-9
I-4-Chloro-3-(Trifluoromethyl)phenyl Isocyanate CAS: 327-78-6
| Igama | 4-Chloro-3-(Trifluoromethyl)phenyl Isocyanate |
| Izithethantonye | Isocyanic Acid 4-Chloro-3-(Trifluoromethyl)phenyl Ester |
| Inombolo yeCAS | 327-78-6 |
| Inombolo yeCAT | RF-PI167 |
| Ubume beStokhwe | Kwi-Stock, iMveliso yoMveliso ukuya kwiiToni |
| Ifomula yeemolekyuli | C8H3ClF3NO |
| Ubunzima beMolekyuli | 221.56 |
| Indawo yokunyibilika | 37.0~42.0℃ (ilayiti.) |
| Indawo yokubilisa | 86.0~90.0℃ 14 mmHg (lit.) |
| Ukuxinana | 1.4720 |
| Iimeko zokuthumela ngenqanawe | I-Ambient |
| Uphawu | Ruifu Chemical |
| Into | Iinkcukacha |
| Imbonakalo | Ikristale emhlophe |
| Ubunyulu / Indlela yokuHlalutya | ≥99.0% (HPLC) |
| Ukuchongwa | (1) IR (2) HPLC |
| Ukufuma (KF) | ≤0.50% |
| Iintsimbi ezinzima | ≤10ppm |
| Ukungcola A | ≤0.15% |
| Ukungcola B | ≤1.0% |
| Ukungcola C | ≤1.0% |
| Okunye Ukungcola Okukodwa | ≤0.50% |
| Ukungcola ngokupheleleyo | ≤1.0% |
| Intsalela yokunyibilika | Itoluene ≤0.089% |
| Umgangatho woVavanyo | Umgangatho woShishino |
| Ukusetyenziswa | Umbindi weSorafenib Tosylate (CAS: 475207-59-1) |
Iphakheji: Ibhotile, ingxowa yefoyile yeAluminiyam, igubu lekhadibhodi, 25kg/Igubu, okanye ngokwemfuno yomthengi.
Imeko yoGcino:Gcina kwizikhongozeli ezivaliweyo kwindawo epholileyo neyomileyo;Khusela ekukhanyeni, ukufuma kunye nokuhlaselwa zizinambuzane.
Umenzi onobunyulu obuPhezulu kunye noMgangatho oZinzile
Ubonelelo ngezoRhwebo i-Sorafenib Tosylate (CAS: 475207-59-1) IziPhakathi eziNxulumeneyo:
I-Sorafenib Tosylate CAS: 475207-59-1
Sorafenib CAS: 284461-73-0
I-4-Chloro-N-Methyl-2-Pyridinecarboxamide CAS: 220000-87-3
I-4-(4-Aminophenoxy)-N-Methylpicolinamide CAS: 284462-37-9
I-4-Chloro-3-(Trifluoromethyl)phenyl Isocyanate CAS: 327-78-6
I-Sorafenib Tosylate (i-CAS: 475207-59-1) luhlobo olutsha lwechiza le-antitumor ekujoliswe kulo, laphuhliswa yi-German Bayer Pharmaceuticals, kwaye yabonisa umsebenzi owandayo we-antitumor kwiimvavanyo zezilwanyana zangaphambili.I-Sorafenib ifumaneka kwiipilisi ze-200-mg zolawulo lomlomo kwaye isetyenziselwa unyango lwe-RCC kunye ne-HCC.I-Sorafenib Tosylate (i-CAS: 475207-59-1) inokuchaphazela ngaxeshanye iiseli ze-tumor kunye nemithambo yegazi ye-tumor.Unempembelelo ephindwe kabini ye-antitumor: inokuthintela iindlela zokudluliselwa komqondiso weseli elamlwa yi-RAF/MEK/ERK ukuthintela ngokuthe ngqo ukukhula kweseli yethumba, ngelixa ikwathintela i-VEGF kunye ne-platelet derived growth factor (PDGF) receptors ukuthintela ukubunjwa kwegazi elitsha lethumba. imikhumbi, ngaloo ndlela inqanda ngokungangqalanga ukukhula iseli ithumba.
