4-Chloro-3-(Trifluoromethyl)phenyl Isocyanate CAS 327-78-6 Ucoceko ≥99.0% Sorafenib Tosylate Intermediate Factory
Ubonelelo ngezoRhwebo i-Sorafenib Tosylate kunye neziPhakathi eziNxulumeneyo:
I-Sorafenib Tosylate CAS: 475207-59-1
Sorafenib CAS: 284461-73-0
I-4-Chloro-N-Methyl-2-Pyridinecarboxamide CAS: 220000-87-3
I-4-(4-Aminophenoxy)-N-Methylpicolinamide CAS: 284462-37-9
I-4-Chloro-3-(Trifluoromethyl)phenyl Isocyanate CAS: 327-78-6
Igama | 4-Chloro-3-(Trifluoromethyl)phenyl Isocyanate |
Izithethantonye | Isocyanic Acid 4-Chloro-3-(Trifluoromethyl)phenyl Ester |
Inombolo yeCAS | 327-78-6 |
Inombolo yeCAT | RF-PI167 |
Ubume beStokhwe | Kwi-Stock, iMveliso yoMveliso ukuya kwiiToni |
Ifomula yeemolekyuli | C8H3ClF3NO |
Ubunzima beMolekyuli | 221.56 |
Indawo yokunyibilika | 37.0~42.0℃ (ilayiti.) |
Indawo yokubilisa | 86.0~90.0℃ 14 mmHg (lit.) |
Ukuxinana | 1.4720 |
Iimeko zokuthumela ngenqanawe | I-Ambient |
Uphawu | Ruifu Chemical |
Into | Iinkcukacha |
Imbonakalo | Ikristale emhlophe |
Ubunyulu / Indlela yokuHlalutya | ≥99.0% (HPLC) |
Ukuchongwa | (1) IR (2) HPLC |
Ukufuma (KF) | ≤0.50% |
Iintsimbi ezinzima | ≤10ppm |
Ukungcola A | ≤0.15% |
Ukungcola B | ≤1.0% |
Ukungcola C | ≤1.0% |
Okunye Ukungcola Okukodwa | ≤0.50% |
Ukungcola ngokupheleleyo | ≤1.0% |
Intsalela yokunyibilika | Itoluene ≤0.089% |
Umgangatho woVavanyo | Umgangatho woShishino |
Ukusetyenziswa | Umbindi weSorafenib Tosylate (CAS: 475207-59-1) |
Iphakheji: Ibhotile, ingxowa yefoyile yeAluminiyam, igubu lekhadibhodi, 25kg/Igubu, okanye ngokwemfuno yomthengi.
Imeko yoGcino:Gcina kwizikhongozeli ezivaliweyo kwindawo epholileyo neyomileyo;Khusela ekukhanyeni, ukufuma kunye nokuhlaselwa zizinambuzane.
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Umenzi onobunyulu obuPhezulu kunye noMgangatho oZinzile
Ubonelelo ngezoRhwebo i-Sorafenib Tosylate (CAS: 475207-59-1) IziPhakathi eziNxulumeneyo:
I-Sorafenib Tosylate CAS: 475207-59-1
Sorafenib CAS: 284461-73-0
I-4-Chloro-N-Methyl-2-Pyridinecarboxamide CAS: 220000-87-3
I-4-(4-Aminophenoxy)-N-Methylpicolinamide CAS: 284462-37-9
I-4-Chloro-3-(Trifluoromethyl)phenyl Isocyanate CAS: 327-78-6
I-Sorafenib Tosylate (i-CAS: 475207-59-1) luhlobo olutsha lwechiza le-antitumor ekujoliswe kulo, laphuhliswa yi-German Bayer Pharmaceuticals, kwaye yabonisa umsebenzi owandayo we-antitumor kwiimvavanyo zezilwanyana zangaphambili.I-Sorafenib ifumaneka kwiipilisi ze-200-mg zolawulo lomlomo kwaye isetyenziselwa unyango lwe-RCC kunye ne-HCC.I-Sorafenib Tosylate (i-CAS: 475207-59-1) inokuchaphazela ngaxeshanye iiseli ze-tumor kunye nemithambo yegazi ye-tumor.Unempembelelo ephindwe kabini ye-antitumor: inokuthintela iindlela zokudluliselwa komqondiso weseli elamlwa yi-RAF/MEK/ERK ukuthintela ngokuthe ngqo ukukhula kweseli yethumba, ngelixa ikwathintela i-VEGF kunye ne-platelet derived growth factor (PDGF) receptors ukuthintela ukubunjwa kwegazi elitsha lethumba. imikhumbi, ngaloo ndlela inqanda ngokungangqalanga ukukhula iseli ithumba.