I-4-Chloro-7-Methoxyquinoline-6-Carboxamide CAS 417721-36-9 Ucoceko >98.5% (HPLC) Lenvatinib Mesylate Intermediate Factory Featured Image

I-4-Chloro-7-Methoxyquinoline-6-Carboxamide CAS 417721-36-9 Ubunyulu > 98.5% (HPLC) I-Lenvatinib Mesylate Intermediate Factory

Inkcazelo emfutshane:

Igama: 4-Chloro-7-Methoxyquinoline-6-Carboxamide

CAS: 417721-36-9

Ubunyulu: >98.5% (HPLC)

Imbonakalo: Okumhlophe-Kumhlophe ukuya kwiPowder eKhanyayo etyheli

Umbindi weLenvatinib Mesylate CAS 857890-39-2

Umgangatho ophezulu, iMveliso yoRhwebo

E-Mail: alvin@ruifuchem.com

Thumela i-imeyile kuthi

Iinkcukacha zeMveliso

Iimveliso ezinxulumeneyo

Iithegi zeMveliso

Inkcazo:

I-Ruifu Chemical Supply Lenvatinib Mesylate Intermediate with High Purity
Lenvatinib Mesylate CAS 857890-39-2
I-4-Chloro-7-Methoxyquinoline-6-Carboxamide CAS 417721-36-9
I-Desquinolinyl Lenvatinib;I-1-(2-Chloro-4-Hydroxyphenyl)-3-Cyclopropylurea CAS 796848-79-8
Methyl 7-Methoxy-4-Oxo-1,4-Dihydroquinoline-6-Carboxylate CAS 205448-65-3
Methyl 4-Amino-2-Methoxybenzoate CAS 27492-84-8
5-(Methoxymethylene) -2,2-Dimethyl-1,3-Dioxane-4,6-Dione CAS 15568-85-1
I-4-Amino-3-Chlorophenol CAS 17609-80-2
I-4-Amino-3-Chlorophenol Hydrochloride CAS 52671-64-4
Methyl 4-Chloro-7-Methoxyquinoline-6-Carboxylate CAS 205448-66-4

Iipropati zeMichiza:

Igama leMchiza	I-4-Chloro-7-Methoxyquinoline-6-Carboxamide
Izithethantonye	I-4-Chloro-7-Methoxy-6-Quinolinecarboxamide;Ukungcola kweLenvatinib 12;Ukungacoceki kweLenvatinib B;Lenvatinib Ukungcola LFS-B
Inombolo yeCAS	417721-36-9
Inombolo yeCAT	RF-PI1971
Ubume beStokhwe	Kwi-Stock, iMveliso yeMveliso ye-50MT / Year
Ifomula yeemolekyuli	I-C11H9ClN2O2
Ubunzima beMolekyuli	236.65
Indawo yokunyibilika	>205℃ (ngoDisemba)
Ukuxinana	1.380±0.060 g/cm3
Uphawu	Ruifu Chemical

Iinkcukacha:

Into	Iinkcukacha
Imbonakalo	I-Off-White ukuya kwiPowder eKhanyayo etyheli
Ubunyulu / Indlela yokuHlalutya	>98.5% (HPLC)
Ilahleko ekomisweni	<0.50%
Intsalela kwi-Ignition	<0.50%
Ukungcola ngokupheleleyo	<1.50%
Proton NMR Spectrum	Iyahambelana noLwakhiwo
Umgangatho woVavanyo	Umgangatho woShishino
Ukusetyenziswa	Umbindi weLenvatinib Mesylate (CAS: 857890-39-2)

Ukupakishwa kunye noGcino:

Iphakheji: Ibhotile, ingxowa yefoyile yeAluminiyam, 25kg/Igubu lekhadibhodi, okanye ngokwemfuno yomthengi

Imeko yoGcino:Gcina kwizikhongozeli ezivaliweyo kwindawo epholileyo neyomileyo;Khusela ukukhanya kunye nokufuma

Izinto eziluncedo:

FAQ:

Isicelo:

I-4-Chloro-7-Methoxyquinoline-6-Carboxamide (i-CAS: 417721-36-9) isetyenziswa kakhulu njenge-intermediate ye-Lenvatinib Mesylate (CAS: 857890-39-2).Iphuhliswe yi-Eisai Inc., i-lenvatinib mesylate yi-vascular endothelial growth factor receptor (VEGF) inhibitor enomsebenzi ochasene ne-VEGF subtypes 1, 2, kunye ne-3 kwaye yamkelwa yi-FDA kwi-2015 yonyango lomhlaza we-thyroid owahlukileyo okhoyo ekuhlaleni. iphindaphinda, i-metastatic, okanye iqhubela phambili kwaye ayizange iphendule kunyango lwe-iodine ye-radioactive.NgoMeyi ka-2016, i-FDA yavuma ichiza njengonyango oludityanisiweyo kunye ne-everolimus kunyango lwe-advanced renal cell carcinoma.Ngenxa yokuba i-VEGF (kunye ne-fibroblast growth factor receptors, eyaziwa ngokuba yi-FGFRs) icingelwa ukuba idlala indima kwi-cardiovascular signaling pathways, i-VEGF2R kunye ne-FGFR inhibition kucingelwa ukuba ziinkqubo ezisemva kwesiphumo sokuqala se-lenvatinib mesylate, i-hypertension.