I-4-Chloro-N-Methyl-2-Pyridinecarboxamide CAS 220000-87-3 Sorafenib Tosylate Factory Intermediate Factory High Purity
Ubonelelo ngezoRhwebo i-Sorafenib Tosylate kunye neziPhakathi eziNxulumeneyo:
I-Sorafenib Tosylate CAS: 475207-59-1
Sorafenib CAS: 284461-73-0
I-4-Chloro-N-Methyl-2-Pyridinecarboxamide CAS: 220000-87-3
I-4-(4-Aminophenoxy)-N-Methylpicolinamide CAS: 284462-37-9
I-4-Chloro-3-(Trifluoromethyl)phenyl Isocyanate CAS: 327-78-6
| Igama leMchiza | I-4-Chloro-N-Methyl-2-Pyridinecarboxamide |
| Izithethantonye | I-4-Chloro-N-Methylpicolinamide;N-Methyl-4-Chloropyridine-2-Carboxamide;I-4-Chloro-N-Methylpyridine-2-Carboxamide |
| Inombolo yeCAS | 220000-87-3 |
| Inombolo yeCAT | RF-PI165 |
| Ubume beStokhwe | Kwi-Stock, iMveliso yoMveliso ukuya kwiiToni |
| Ifomula yeemolekyuli | C7H7ClN2O |
| Ubunzima beMolekyuli | 170.60 |
| Indawo yokunyibilika | 41.0 ~ 438.0℃ |
| Indawo yokubilisa | 317.8℃ ku-760 mmHg |
| Ukuxinana | 1.264 g/cm3 |
| Ukunyibilika (Nyibilika ngaphakathi) | I-Methanol, i-Ethylacetate |
| Iimeko zokuthumela ngenqanawe | I-Ambient |
| Uphawu | Ruifu Chemical |
| Into | Iinkcukacha |
| Imbonakalo | I-Off-White ukuya kwiPowder eKhanyayo etyheli |
| Ukuchongwa | (1) MS (2) 1H-NMR |
| Ubunyulu / Indlela yokuHlalutya | 98.0% ~ 101.0% (kwisiseko esomileyo) (HPLC) |
| Ukufuma (KF) | ≤1.0% |
| Ilahleko ekomisweni | ≤1.0% |
| Iintsimbi ezinzima | ≤20ppm |
| Ukungacoceki Okukodwa | ≤1.0% |
| Ukungcola ngokupheleleyo | ≤2.0% |
| Umgangatho woVavanyo | Umgangatho woShishino |
| Ukusetyenziswa | Umbindi weSorafenib Tosylate (CAS: 475207-59-1) |
Iphakheji: Ibhotile, ingxowa yefoyile yeAluminiyam, igubu lekhadibhodi, 25kg/Igubu, okanye ngokwemfuno yomthengi.
Imeko yoGcino:Gcina kwizikhongozeli ezivaliweyo kwindawo epholileyo neyomileyo;Khusela ekukhanyeni, ukufuma kunye nokuhlaselwa zizinambuzane.
I-Shanghai Ruifu Chemical Co., Ltd. ngumenzi ohamba phambili kunye nomthengisi we-4-Chloro-N-Methyl-2-Pyridinecarboxamide (CAS: 220000-87-3) enomgangatho ophezulu, yinto ephakathi ngokuqhelekileyo kwi-synthesis ye-Sorafenib Tosylate ( I-CAS: 475207-59-1).I-Sorafenib Tosylate luhlobo olutsha lwechiza le-antitumor ekujoliswe kulo, laphuhliswa yi-German Bayer Pharmaceuticals, kwaye libonise umsebenzi owandayo wokulwa nethumba kuvavanyo lwezilwanyana zangaphambi kweklinikhi.I-Sorafenib ifumaneka kwiipilisi ze-200-mg zolawulo lomlomo kwaye isetyenziselwa unyango lwe-RCC kunye ne-HCC.I-Sorafenib Tosylate (i-CAS: 475207-59-1) inokuchaphazela ngaxeshanye iiseli ze-tumor kunye nemithambo yegazi ye-tumor.
