I-4-Hydroxycoumarin CAS 1076-38-6 Ubunyulu > 99.0% (HPLC)
I-Shanghai Ruifu Chemical Co., Ltd. ngumenzi ohamba phambili we-4-Hydroxycoumarin (i-CAS: 1076-38-6) enomgangatho ophezulu.I-Ruifu Chemical inokubonelela ngenkonzo yehlabathi jikelele, ixabiso elikhuphisanayo, amancinci kunye nenani elikhulu elikhoyo.Thenga i-4-Hydroxycoumarin,Please contact: alvin@ruifuchem.com
| Igama leMchiza | 4-Hydroxycoumarin |
| Izithethantonye | 4-Hydroxy-1-Benzopyran-2-enye;I-4-Coumarinyl Utywala;I-4-Coumarinol;4-Hydroxy-2H-Benzo[b]pyran-2-enye;I-4-Hydroxy-2H-Chromen-2-enye;4-Hydroxychromen-2-enye;Benzotronic Acid |
| Ubume beStokhwe | Kwi-Stock, Kwenziwa uRhwebo |
| Inombolo yeCAS | 1076-38-6 |
| Ifomula yeemolekyuli | C9H6O3 |
| Ubunzima beMolekyuli | 162.14 g/mol |
| Indawo yokunyibilika | 213.0~217.0℃(lit.) |
| Ukuxinana | 1.446 |
| Ukunyibilika kwamanzi | Ayinyibilikiyo emanzini |
| Ukunyibilika | Inyibilika kwi-Ethanol kunye ne-Dimethyl Formamide |
| Ugcino Temp. | Indawo epholileyo kunye neyomileyo |
| I-COA kunye ne-MSDS | Iyafumaneka |
| Udidi | AbaPhakathi bamayeza |
| Uphawu | Ruifu Chemical |
| Izinto | ImiGangatho yokuHlola | Iziphumo |
| Imbonakalo | Umgubo weCrystalline oMhlophe okanye ophantse wamhlophe | Iyahambelana |
| Indawo yokunyibilika | 213.0 ~ 217.0℃ | 213.6 ~ 214.7℃ |
| Ilahleko ekomisweni | <0.50% | 0.32% |
| Intsalela kwi-Ignition | <0.20% | 0.08% |
| Iintsimbi ezinzima (Pb) | ≤10ppm | <10ppm |
| Ukungacoceki Okukodwa | <0.30% | Iyahambelana |
| Ubunyulu / Indlela yokuHlalutya | >99.0% (HPLC) | 99.64% |
| I-Infrared Spectrum | Iyahambelana neSakhiwo | Iyahambelana |
| I-1 H NMR Spectrum | Iyahambelana neSakhiwo | Iyahambelana |
| Ukuqukumbela | Imveliso ivavanyiwe kwaye iyahambelana neenkcukacha ezinikiweyo | |
Umqulu:Ibhotile, ingxowa yefoyile yeAluminiyam, 25kg/Igubu lekhadibhodi, okanye ngokwemfuno yomthengi.
Imeko yoGcino:Gcina kwisitya esivaliweyo.Gcina kwindawo epholileyo, eyomileyo kwaye engenamoya.Khusela ukukhanya kunye nokufuma.Ayihambelani ne-oxidizing agents ezinamandla kunye neziseko ezinamandla.
Ukuhambisa ngenqanawe:Zisa kwihlabathi liphela ngomoya, ngeFedEx / DHL Express.Ukubonelela ngokukhawuleza nangokuthembekileyo.
4 Indlela yokuvavanya
4.1 Imbonakalo (ukuhlolwa okubonwayo)
4.2 Ilahleko ekomisweni
4.3 Ukumiselwa komxholo we-4-Hydroxycoumarin
4.3.1 Indlela yokumisela
Iisampulu zinyibilike kwisigaba esihambahambayo kwaye zimiselwe yichromatography yolwelo oluphezulu olusebenzayo kwikholamu ye-C18 ngeyona ndlela iphakamileyo yokulinganisa indawo.
4.3.2 I-Reagent
a) I-acetonitrile: i-chromatographic ecocekileyo (engeniswe ngaphandle);
b) Amanzi: Amanzi adiyiziweyo okanye amanzi adiliweyo esibini.
4.3.3 Isixhobo
a) Ukusebenza okuphezulu kwechromatography yolwelo;
b) I-spectrometer ye-wavelength ehlengahlengiswayo ye-UV;
c) Ikholam yohlalutyo: ikholam ye-C18;
d) Ii-oscillators ze-Ultrasonic.
4.3.4 Iimeko zokusebenza zeChromatographic
a) Isigaba seselula: i-acetonitrile: amanzi: i-phosphoric acid = 700:300:1 (V/V/ V);
b) Izinga lokuhamba: 1.0ml / min;
c) Ubushushu bekholamu: ubushushu begumbi;
d) Ukubona ubude bobude: 254nm
e) Ubungakanani besampuli: 20μL
4.3.5 Ukulungiswa kwesisombululo sovavanyo
Ukulinganisa isampula ye-20mg (echanekileyo ukuya kwi-0.002g), yibeke kwibhotile ye-volumetric ye-25ml, yichithe ngesigaba seselula kwi-4.2.4 a) kwisikali, yigubungele kakuhle kwi-shaker ye-ultrasonic ukuze isetyenziswe kamva.
4.3.6 Ukumiselwa komxholo
Ngaphantsi kweemeko ze-4.3.4 ngasentla, isisombululo sokuvavanya siya kugqitywa emva kokuba isixhobo sizinzile.
4.3.7 Ukubala
Incopho yendawo yokulinganisa isetyenziselwe ukubala iziphumo.
4.3.8 Ukutenxa okuvumelekileyo
Ukuphambuka kwemilinganiselo emibini akukho ngaphezu kwe-0.5%, kwaye ixabiso eliphakathi elibaliweyo lithathwa njengesiphumo sovavanyo.
4.4 Ukumiselwa kwendawo yokunyibilika.
5 Imithetho Yokuhlola
5.1 Ibhetshi nganye yeemveliso iya kuvavanywa lisebe lokuhlola umgangatho ngokwezinto ezikulo mgangatho phambi kokushiya umzi-mveliso.
5.2 Ukumiselwa kweebhetshi
Ibhetshi yeemveliso eziveliswe ngobuninzi bokutyisa (malunga nama-200kg).
5.3 Iisampulu
Iingxowa ezimbini (imigqomo) zikhethwe ngokungenamkhethe kwipakethe yebhetshi nganye yeemveliso.Emva kwesampuli kunye nokuxuba ngokulinganayo, zihlulwe zibe yi-50g ngendlela yamacandelo amane, ahlulwe abe ngamacandelo amabini, enye isetyenziselwa ukuvavanya kwaye enye igcinwe ukuze isetyenziswe.
5.4 Isigqibo
Ibhetshi nganye yeemveliso iya kuvavanywa ngokweemfuno ezibekwe kulo mgangatho.Ukuba nayiphi na into iyasilela ukuhlangabezana neemfuno ezichazwe kulo mgangatho, iyakuvunyelwa ukuba iphinde ivavanywe kwakhona ngesampulu ephindiweyo.Ukuba kusekho into enye engaphumeleliyo ekufezekiseni iimfuno ezichazwe kulo mgangatho, ibhetshi yeemveliso iya kugwetywa ingafanelekanga.
5.5 Ulamlo
Umsebenzisi unelungelo lokuqhuba ukuhlolwa kokwamkelwa kwiintsuku ze-15 emva kokufumana iimpahla ngokuhambelana nemimiselo yalo mgangatho.Kwimeko yayo nayiphi na inkcaso esemgangathweni, omabini amaqela angathethathethana ukuze asonjululwe, okanye aphathise iziko lolamlo elisemthethweni ekuvunyelwene ngalo ngamaqela omabini ukuba liqhube ulamlo ngokwezibonelelo zalo mgangatho.
6 iilebhile kunye neelebhile
La manqaku alandelayo aya kuncanyathiselwa kwiphakheji yemveliso:
a) Igama lemveliso;
b) Inombolo eqhelekileyo;
c) Ubunzima beNet;
d) Umhla wemveliso okanye inombolo yebhetshi;
e) Igama nedilesi yomzi-mveliso;
f) Ubomi beshelufu.
Ukuthenga njani?Nceda uqhagamshelaneDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
Amava Eminyaka Eli-15?Sineminyaka engaphezu kwe-15 yamava ekwenziweni nasekuthumeleni kumazwe angaphandle uluhlu olubanzi oluphezulu lwamayeza aphakathi okanye amachiza alungileyo.
Iimarike eziphambili?Thengisa kwimarike yasekhaya, eMntla Melika, eYurophu, eIndiya, eKorea, eJapan, eOstreliya, njl.
Iingenelo?Umgangatho ophezulu, ixabiso elifikelelekayo, iinkonzo zengcali kunye nenkxaso yobugcisa, ukuhanjiswa ngokukhawuleza.
UmgangathoIsiqinisekiso?Inkqubo yokulawula umgangatho ongqongqo.Izixhobo zobuchwephesha zokuhlalutya ziquka i-NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, njl.
Iisampulu?Uninzi lweemveliso zibonelela ngeesampulu zasimahla zokuvavanya umgangatho, iindleko zokuthumela kufuneka zihlawulwe ngabathengi.
Factory Audit?Uphicotho-zincwadi lwasefektri wamkelekile.Nceda wenze idinga kwangaphambili.
MOQ?Akukho MOQ.Umyalelo omncinci wamkelekile.
Ixesha lokuzisa? Ukuba ngaphakathi kwesitokhwe, ukuhanjiswa kweentsuku ezintathu kuqinisekisiwe.
Ezothutho?Nge-Express (FedEx, DHL), ngoMoya, ngoLwandle.
Amaxwebhu?Emva kwenkonzo yokuthengisa: I-COA, i-MOA, i-ROS, i-MSDS, njl.
Udibaniso lweSiko?Inokubonelela ngeenkonzo zesiko lokudibanisa ukuze zilungele iimfuno zakho zophando.
Immimiselo yokuhlawula?I-invoyisi yeProforma iya kuthunyelwa kuqala emva kokuqinisekiswa kwe-odolo, efakwe kwiinkcukacha zethu zebhanki.Intlawulo nge-T / T (i-Telex Transfer), i-PayPal, i-Western Union, njl.
Iikhowudi zoMngcipheko
I-R22 - Iyingozi xa iginyiwe
R36/37/38 - Ukucaphukisa emehlweni, inkqubo yokuphefumla kunye nolusu.
Inkcazelo yoKhuseleko
S26 - Xa udibana namehlo, hlambulula ngokukhawuleza ngamanzi amaninzi kwaye ufune iingcebiso zonyango.
S36 - Nxiba iimpahla ezifanelekileyo zokukhusela.
WGK eJamani 3
RTECS DJ3100000
TSCA Ewe
Ikhowudi yeHS 2932201000
I-Hazard Note irritant
I-4-Hydroxycoumarin (i-CAS: 1076-38-6) i-hydroxycoumarin eyi-coumarin apho i-hydrogen kwindawo ye-4 ithathelwa indawo liqela le-hydroxy.I-asidi ye-conjugate ye-4-hydroxycoumarin (1-).
I-4-Hydroxycoumarin sisityalo esiphuma kwi-antioxidant, sikhusela kwi-lipid peroxidation, kunye ne-inhibitor enokubakho ye-HIV-1 Integrase.I-4-Hydroxycoumarins ludidi olubaluleke kakhulu lwamachiza e-biologically asebenzayo asetyenziswa ngokubanzi njenge-anticoagulants-Warfarin kunye ne-Acenocoumarol.
I-4-Hydroxycoumarin, i-coumarin derivative, yenye yezona zinto zixhaphakileyo ze-heterocyclic scaffolds kwaye isetyenziswa rhoqo kwi-synthesis ye-organic compounds.I-4-Hydroxycoumarin inazo zombini iimpawu ze-electrophilic kunye ne-nucleophilic.I-4-i-Hydroxycoumarin derivatives iqeshwe njenge-anticoagulant, i-antibacterial, i-antifungal, i-antiviral, i-antitumor, i-antiprotozoal, i-insecticidal, i-antimycobacterial, i-antimutagenic, i-antioxidant, i-anti-inflammatory agents, i-HIV protease inhibitors kunye ne-tyrosine kinase inhibitors.
I-4-Hydroxycoumarin ibandakanyeka kwi-annulation reactions, ngenxa ye-acidity ephezulu ye-CH bond kwi-3-position: i-reaction yamacandelo amathathu kunye ne-isocyanides kunye ne-dialkyl acetylene dicarboxylates inikezela i-4H-pyrans e-annulated.
I-4-Hydroxycoumarin liyeza eliphakathi kunye nesibulali zinambuzane.
I-4-Hydroxycoumarin ikwasisinongo, kwaye i-coumarins isasazwe ngokubanzi kubukumkani bezityalo.
