4-(Methylthio)phenylacetic Acid CAS 16188-55-9 Ubunyulu>98.0% (GC) Etoricoxib Intermediate

Inkcazelo emfutshane:

Igama leKhemikhali: 4-(Methylthio)phenylacetic Acid

CAS: 16188-55-9

Ubunyulu: >98.0% (GC)

Imbonakalo: Umgubo oMhlophe ukuya kokuKhanyayo oMthubi

Umbindi we-Etoricoxib (CAS: 202409-33-4)

Qhagamshelana: UGqr. Alvin Huang

Iselula/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com


Iinkcukacha zeMveliso

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Iithegi zeMveliso

Inkcazo:

I-Shanghai Ruifu Chemical Co., Ltd. ngumenzi ohamba phambili kunye nomthengisi we-4-(Methylthio) phenylacetic Acid (CAS: 16188-55-9) enomgangatho ophezulu.Sinokubonelela nge-COA, ukuhanjiswa kwehlabathi jikelele, ubuninzi obuncinci kunye nobuninzi obukhoyo.Ukuba unomdla kule mveliso, nceda uthumele ulwazi oluneenkcukacha lubandakanya inombolo ye-CAS, igama lemveliso, ubuninzi kuthi.Please contact: alvin@ruifuchem.com 

Iipropati zeMichiza:

Igama leMchiza 4-(Methylthio)phenylacetic Acid
Izithethantonye I-4-Methylthiophenylacetic Acid;2-(4-(Methylthio)phenyl)acetic Acid;2-[4-(Methylsulfanyl)phenyl]acetic Acid;4-(Methylthio)benzeneacetic Acid
Inombolo yeCAS 16188-55-9
Inombolo yeCAT RF-PI1183
Ubume beStokhwe Kwi-Stock, iMveliso yoMveliso ukuya kwiiToni
Ifomula yeemolekyuli I-C9H10O2S
Ubunzima beMolekyuli 182.24
Indawo yokunyibilika 96.0~99.0℃ (ilayiti.)
Indawo yokubilisa 337.4±25.0℃ (isibane.)
Ukuxinana 1.23±0.10 g/cm3
Uphawu Ruifu Chemical

Iinkcukacha:

Into Iinkcukacha
Imbonakalo Umgubo oMhlophe ukuya koMthubi oKhanyayo
Ubunyulu / Indlela yokuHlalutya >98.0% (GC)
Ubunyulu / Indlela yokuHlalutya >98.0% (iNeutralization Titration)
Indawo yokunyibilika 96.0~99.0℃
Ilahleko ekomisweni <1.00%
Intsalela kwi-Ignition <0.50%
Ukungcola ngokupheleleyo <2.00%
Umgangatho woVavanyo Umgangatho woShishino
Ukusetyenziswa Umbindi we-Etoricoxib (CAS: 202409-33-4)

Ukupakishwa kunye noGcino:

Iphakheji: Ibhotile, ingxowa yefoyile yeAluminiyam, 25kg/Igubu lekhadibhodi, okanye ngokwemfuno yomthengi

Imeko yoGcino:Gcina kwizikhongozeli ezivaliweyo kwindawo epholileyo neyomileyo;Khusela ukukhanya kunye nokufuma

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Isicelo:

I-4-(Methylthio) i-phenylacetic Acid (i-CAS: 16188-55-9) iyona nto ingundoqo ephakathi ukulungiselela i-Etoricoxib (i-CAS: 202409-33-4).I-Etoricoxib luhlobo lwe-cyclooxygenase-2 (COX-2) inhibitors ekhethiweyo kakhulu eyenziwe yinkampani ye-Merck enegama lekhemikhali engu-5-chloro-6'-methyl-3-4-(methanesulfonamide) phenyl] -2, 3'- i-bipyridine.I-Etoricoxib inokwakheka kweekhemikhali ezikhethekileyo kwiqela le-methylsulfonyl.Ukuqaliswa kweli qela akukwazi ukunyusa kuphela ukukhethwa kweziyobisi ze-COX-2, kodwa kwakhona akuvelisi iziyobisi ze-sulfa kunye ne-cross-allergic reactions.I-Etoricoxib isetyenziswa ngokubanzi kunyango lwe-osteoarthritis (OA), isifo samathambo, isifo samathambo, i-ankylosing spondylitis, iintlungu ezinganyangekiyo ezisezantsi, i-acute gouty arthritis, i-dysmenorrhea ephambili kunye neentlungu zasemva kokuhlinzwa, kunye nezinye izifo.

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