4,6-Dimethyl-2-(Methylsulfonyl)pyrimidine CAS 35144-22-0 Ubunyulu ≥99.0% (HPLC) Factory

Inkcazelo emfutshane:

4,6-Dimethyl-2- (Methylsulfonyl) pyrimidine

CAS: 35144-22-0

Imbonakalo: Umgubo weCrystalline oMthubi

Ubunyulu: ≥99.0% (HPLC)

I-API ephakathi (i-CAS: 177036-94-1) kunyango lwe-Pulmonary Arterial Hypertension (PAH)

Qhagamshelana: UGqr. Alvin Huang

Iselula/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com

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Iinkcukacha zeMveliso

Iimveliso ezinxulumeneyo

Iithegi zeMveliso

Inkcazo:

Ubonelelo ngezoRhwebo (CAS: 177036-94-1) abaPhakathi abaNxulumeneyo:
CAS: 177036-94-1
I-Methyl 2-Hydroxy-3-Methoxy-3,3-Diphenylpropanoate CAS: 178306-47-3
I-2-Hydroxy-3-Methoxy-3,3-Diphenylpropanoic Acid CAS: 178306-51-9
(S)-2-Hydroxy-3-Methoxy-3,3-Diphenylpropionic Acid CAS: 178306-52-0
L-Proline Methyl Ester Hydrochlorid CAS: 2133-40-6
4,6-Dimethyl-2-(Methylsulfonyl)pyrimidine CAS: 35144-22-0

Iipropati zeMichiza:

Igama leMchiza	4,6-Dimethyl-2- (Methylsulfonyl) pyrimidine
Ushunqulelo	I-DLMSP
Inombolo yeCAS	35144-22-0
Ubume beStokhwe	Kwi-Stock, iMveliso yoMveliso ukuya kwiiToni
Ifomula yeemolekyuli	I-C7H10N2O2S
Ubunzima beMolekyuli	186.23
Indawo yokunyibilika	80.0 ~ 84.0℃
Ukuxinana	1.239g/cm3
Ukunyibilika (Nyibilika ngaphakathi)	IMethanol
I-COA kunye ne-MSDS	Iyafumaneka
Isampulu	Iyafumaneka
Imvelaphi	Shanghai, China
Uphawu	Ruifu Chemical

Iinkcukacha:

Into	Iinkcukacha	Iinkcukacha
Imbonakalo	Umgubo weCrystalline otyheli	Umgubo weCrystalline otyheli
Ubunyulu / Indlela yokuHlalutya	≥99.0% (HPLC)	99.60%
Indawo yokunyibilika	80.0 ~ 84.0℃	80.0 ~ 82.0℃
Ukufuma (KF)	≤0.50%	0.33%
Intsalela kwi-Ignition	≤0.30%	0.09%
Ukungacoceki Okukodwa	≤0.50%	<0.50%
Iintsimbi ezinzima	≤20ppm	<20ppm
I-1 H NMR Spectrum	Ngokungqinelana noLwakhiwo	Iyahambelana
Ukuqukumbela	Imveliso ivavanyiwe kwaye ihambelana neenkcukacha ezinikiweyo
Usetyenziso oluphambili	I-Intermediate ye-API (CAS: 177036-94-1)

I-4,6-Dimethyl-2- (Methylsulfonyl) pyrimidine (CAS: 35144-22-0) Indlela yokwenziwa

Ukupakishwa kunye noGcino:

Umqulu:Ibhotile, ingxowa yefoyile yeAluminiyam, 25kg/Igubu lekhadibhodi, okanye ngokwemfuno yomthengi.
Imeko yoGcino:Gcina isikhongozeli sivaliwe kwaye usigcine kwindawo epholileyo, eyomileyo nengena umoya kakuhle kude nezinto ezingahambelaniyo.Khusela ukukhanya kunye nokufuma.
Ukuhambisa ngenqanawe:Zisa kwihlabathi liphela ngomoya, ngeFedEx / DHL Express.Ukubonelela ngokukhawuleza nangokuthembekileyo.

Izinto eziluncedo:

FAQ:

35144-22-0 - Umngcipheko kunye noKhuseleko:

Iimpawu zeHazard Xi - Irritant
Iikhowudi zoMngcipheko
36/37/38 - Ukucaphukisa emehlweni, inkqubo yokuphefumula kunye nesikhumba.
Inkcazelo yoKhuseleko
S26 - Xa udibana namehlo, hlambulula ngokukhawuleza ngamanzi amaninzi kwaye ufune iingcebiso zonyango.
S36 - Nxiba iimpahla ezifanelekileyo zokukhusela.

35144-22-0 - Isicelo:

I-Shanghai Ruifu Chemical Co., Ltd. ngumenzi ohamba phambili kunye nomthengisi we-4,6-Dimethyl-2- (Methylsulfonyl) pyrimidine (CAS: 35144-22-0) kunye nomgangatho ophezulu.I-pharmaceutical Intermediate ingasetyenziswa kwi-synthesis ye-API (CAS: 177036-94-1).(I-CAS: 177036-94-1) ngumchasi we-endothelin-A (ETA) okhethiweyo owaziswa kunyango lomlomo lwezigulane ezine-pulmonary arterial hypertension (PAH), ukuphucula umthamo wokuzilolonga kunye nokulibaziseka kweklinikhi.Ngumchasi wesithathu we-ET-receptor oza kuthengiswa ngolu phawu emva kwe-bosentan kunye ne-sitaxsentan.I-PAH isifo esinqabileyo semibhobho encinci ye-pulmonary ebonakaliswe ngokunyuka kwe-vascular and remodeling, okubangelwa ukunyuka okuqhubekayo kwi-pulmonary vascular resistance and pulmonary arterial pressure, kwaye ekugqibeleni, ukungaphumeleli kwe-ventricular kunye nokufa kwangaphambi kwexesha.Iimpawu zakwangoko ze-PAH ziquka ukuphelelwa ngumphefumlo ngokuthe ngcembe, ukudinwa, ukubetha kwentliziyo, ukudumba, nokuquleka.