5-Amino-1-(2-Hydroxyethyl)pyrazole CAS 73616-27-0 Ubunyulu >99.0% (HPLC) Cefoselis Intermediate
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Igama leMchiza | 5-Amino-1-(2-Hydroxyethyl)pyrazole |
Izithethantonye | 3-Aminopyrazole-2-Ethanol;3-Amino-2-Pyrazoleethanol;5-Amino-1-(beta-Hydroxyethyl)pyrazole |
Inombolo yeCAS | 73616-27-0 |
Inombolo yeCAT | RF2586 |
Ubume beStokhwe | Kwi-Stock, iMveliso yoMveliso ukuya kwiiToni |
Ifomula yeemolekyuli | I-C5H9N3O |
Ubunzima beMolekyuli | 127.15 |
Indawo yokunyibilika | 107.0 ukuya 109.0℃ |
Indawo yokubilisa | 140℃/0.04 mmHg |
Ukuxinana | 1.35±0.10 g/cm3 |
Inovakalelo | Ukungeva kuMoya, Ubushushu abuva |
Uphawu | Ruifu Chemical |
Into | Iinkcukacha |
Imbonakalo | Umgubo oMthubi oKhanyayo ukuya koBomvu oMthubi |
Ubunyulu / Indlela yokuHlalutya | >99.0% (HPLC) |
Ubunyulu / Indlela yokuHlalutya | >98.0% (Nonaqueous Titration) |
Indawo yokunyibilika | 107.0 ukuya 109.0℃ |
Ilahleko ekomisweni | <0.50% |
Ukungcola ngokupheleleyo | <1.00% |
I-1 H NMR Spectrum | Ukungqinelana Nolwakhiwo |
Ukusetyenziswa | I-Intermediates of Cefoselis (CAS: 122841-10-5) & Cefoselis Sulfate (CAS: 122841-12-7) |
Iphakheji: Ibhotile, ingxowa yefoyile yeAluminiyam, 25kg/Igubu lekhadibhodi, okanye ngokwemfuno yomthengi
Imeko yoGcino:Gcina kwizikhongozeli ezivaliweyo kwindawo epholileyo neyomileyo;Khusela ukukhanya kunye nokufuma
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I-5-Amino-1- (2-Hydroxyethyl) pyrazole (CAS: 73616-27-0) yi-intermediates ye-Cefoselis (CAS: 122841-10-5) kunye ne-Cefoselis Sulfate (CAS: 122841-12-7).I-Cefoselis sisizukulwana esitsha se-cephalosporin sesizukulwana sesine kwaye yasungulwa eJapan njengeyeza lokubulala iintsholongwane kubazali kwiintlobo ezahlukeneyo zosulelo oluquka i-Staphylococcus aureus (ingakumbi i-MRSA ekwaziyo ukumelana ne-methicillin) kunye ne-Pseudornonas aeruginosa.Iyakwazi ukulungiswa kwiindlela ezi-3 ezinxulumene nazo, zonke zisebenzisa i-2-pyrazolomethyl-3-cephem-4-carboxylic njengento engundoqo ephakathi.Kwizifundo zangaphambi kweklinikhi, i-Cefolesis yayine-MIC50 engcono kune-Ceftazidime ngokuchasene ne-Streptococcus pneurnoniae okanye i-Staphflococcus aureus (i-methicillin-sensitive MSSA okanye i-MRSA exhathisayo) kwaye yabonisa umsebenzi obalulekileyo wokulwa ne-antibacterial ngokuchasene ne-Citrobacter kunye ne-Enterobacter.I-Cefolesis inyamezeleka kakuhle kwizifundo zeklinikhi, isuswa ikakhulu ngokuhluzwa kweglomerular ebantwini.