5-Bromo-2-Chloro-N-Cyclopentylpyrimidin-4-Amine CAS 733039-20-8 Ubunyulu > 99.0% (HPLC) Palbociclib Intermediate Factory
I-Ruifu Chemical Supply Palbociclib Related Intermediates:
Palbociclib CAS 571190-30-2
5-Bromo-2,4-Dichloropyrimidine CAS 36082-50-5
I-5-Bromo-2-Chloro-N-Cyclopentylpyrimidin-4-Amine CAS 733039-20-8
tert-Butyl 4-(6-Nitropyridin-3-yl)piperazine-1-Carboxylate CAS 571189-16-7
tert-Butyl 4-(6-Amino-3-Pyridyl)piperazine-1-Carboxylate CAS 571188-59-5
6-Bromo-2-Chloro-8-Cyclopentyl-5-Methylpyrido-[2,3-d]pyrimidin-7 (8H)-enye CAS 1016636-76-2
I-2-Chloro-8-Cyclopentyl-5-Methyl-8H-Pyrido[2,3-d]pyrimidin-7-enye CAS 1013916-37-4
Igama leMchiza | 5-Bromo-2-Chloro-N-Cyclopentylpyrimidin-4-Amine |
Izithethantonye | N-(5-Bromo-2-Chloropyrimidin-4-yl)(cyclopentyl)amine;5-Bromo-2-Chloro-4-(Cyclopentylamino)pyrimidine |
Inombolo yeCAS | 733039-20-8 |
Inombolo yeCAT | RF-PI1851 |
Ubume beStokhwe | Kwi-Stock, iMveliso yoMveliso ukuya kwiiToni |
Ifomula yeemolekyuli | I-C9H11BrClN3 |
Ubunzima beMolekyuli | 276.56 |
Uphawu | Ruifu Chemical |
Into | Iinkcukacha |
Imbonakalo | Mhlophe ukuya kwi-Off-White Powder |
Ubunyulu / Indlela yokuHlalutya | >99.0% (HPLC) |
I-1 H NMR Spectrum | Ukungqinelana Nolwakhiwo |
Ilahleko ekomisweni | <1.00% |
Ukungcola ngokupheleleyo | <1.00% |
Umgangatho woVavanyo | Umgangatho woShishino |
Ukusetyenziswa | Umbindi wePalbociclib (CAS: 571190-30-2) |
Iphakheji: Ibhotile, ingxowa yefoyile yeAluminiyam, 25kg/Igubu lekhadibhodi, okanye ngokwemfuno yomthengi
Imeko yoGcino:Gcina kwizikhongozeli ezivaliweyo kwindawo epholileyo neyomileyo;Khusela ukukhanya kunye nokufuma
I-5-Bromo-2-Chloro-N-Cyclopentylpyrimidin-4-Amine (i-CAS: 733039-20-8) ingasetyenziselwa njengendawo ephakathi kwePalbociclib (CAS: 571190-30-2).Palbociclib (igama lorhwebo: Ibrance)yi-inhibitor ekhethiweyo ye-cyclin-dependent kinases CDK4 kunye ne-CDK6.I-Palbociclib i-kinase inhibitor eboniswe kunyango lwe-hormone receptor (HR) -positive, i-epidermal growth factor receptor 2 (HER2) -negative eziphambili okanye umdlavuza webele we-metastatic ngokudibanisa: I-aromatase inhibitor njengonyango lokuqala olusekelwe kwi-endocrine kubasetyhini be-postmenopausal;okanye i-Fulvestrant kubasetyhini abanokukhula kwesifo emva konyango lwe-endocrine.