I-5-Bromoacetyl-2-Hydroxybenzaldehyde CAS 115787-50-3 Salmeterol Intermediate
Ubonelelo lwabavelisi ngoBusulungekileyo obuPhezulu kunye noMgangatho oZinzileyo
Igama leMichiza: 5-Bromoacetyl-2-Hydroxybenzaldehyde
CAS: 115787-50-3
Umgangatho ophezulu, iMveliso yoRhwebo
Igama leMchiza | I-5-Bromoacetyl-2-Hydroxybenzaldehyde |
Izithethantonye | I-5-(2-Bromoacetyl) -2-Hydroxybenzaldehyde;5-(Bromoacetyl)salicylaldehyde |
Inombolo yeCAS | 115787-50-3 |
Inombolo yeCAT | RF-PI343 |
Ubume beStokhwe | Kwi-Stock, iMveliso yoMveliso ukuya kwiiToni |
Ifomula yeemolekyuli | C9H7BrO3 |
Ubunzima beMolekyuli | 243.05 |
Ukunyibilika | Dichloromethane, Ethyl Acetate |
Uphawu | Ruifu Chemical |
Into | Iinkcukacha |
Imbonakalo | Umgubo weCrystalline oMhlophe okanye otyheli |
Ukufuma (Ngu-KF) | ≤0.50% |
Indlela yoVavanyo / yoHlahlelo | ≥97.0% (HPLC) |
Ukungcola ngokupheleleyo | ≤3.0% |
Umgangatho woVavanyo | Umgangatho woShishino |
Ukusetyenziswa | abaPhakathi bamayeza;Umbindi weSalmeterol, iAntiasthmatic |
Iphakheji: Ibhotile, ingxowa yefoyile yeAluminiyam, igubu lekhadibhodi, 25kg/Igubu, okanye ngokwemfuno yomthengi.
Imeko yoGcino:Gcina kwizikhongozeli ezivaliweyo kwindawo epholileyo neyomileyo;Khusela ekukhanyeni, ukufuma.
I-5-Bromoacetyl-2-Hydroxybenzaldehyde (i-CAS: 115787-50-3) yeyona nto iphakathi ekulungiseleleni iSalmeterol (S090100).I-Salmeterol liyeza le-asthma.Iphuhliswa kwi-molecular structure ye-salbutamol kunye nenxalenye yomsila owongezelelweyo kuphela.Le nxalenye ihambelana ngokusondeleyo nesakhiwo esithile se-beta 2 receptor, indawo ye-receptor yangaphandle.Oku kuvumela ezinye iindawo ze-molecule ukuba zisebenze ngokukhululekile kwi-beta 2 receptor.Kwaye ngenxa yesi sizathu, le mveliso inokuqhubeka nokuhlala kwindawo yesenzo.I-Salmeterol ingasetyenziselwa njenge-bronchodilator ye-beta-2 ye-receptor agonists yexesha elide ekulawuleni imihla ngemihla iimpawu ze-asthma.Ingasetyenziselwa unyango lwexesha elide lwe-asthma (kubandakanya i-asthma yasebusuku kunye ne-asthma-induced asthma), ukuvinjelwa kwendlela yomoya ebuyiselwayo kwi-bronchitis engapheliyo kunye ne-emphysema, kwaye ayifanelekanga ukuhlaselwa kwe-asthma.