I-5-Cyanoindole CAS 15861-24-2 Ubunyulu > 99.0% (HPLC) Factory
AbaPhakathi abaNxulumene noBonelelo loMvelisi
5-Cyanoindole CAS 15861-24-2
3-(4-Chlorobutyl)-5-Cyanoindole CAS 143612-79-7
I-Ethyl 5-Nitrobenzofuran-2-Carboxylate CAS 69604-00-8
Ethyl 5-Aminobenzofuran-2-Carboxylate CAS 174775-48-5
5-(Piperazin-1-yl)benzofuran-2-Carboxamide CAS 183288-46-2
I-CAS 163521-08-2
Igama leMchiza | 5-Cyanoindole |
Izithethantonye | 5-Cyano-1H-Indole;Indoline-5-Carbonitrile;1H-Indole-5-Carbonitrile |
Inombolo yeCAS | 15861-24-2 |
Inombolo yeCAT | RF-PI1493 |
Ubume beStokhwe | Kwi-Stock, iMveliso yoMveliso ukuya kwiiToni |
Ifomula yeemolekyuli | C9H6N2 |
Ubunzima beMolekyuli | 142.16 |
Indawo yokunyibilika | 106.0~108.0℃ (ilayiti.) |
Ukunyibilika | Inyibilika kwiChloroform, iHexane kunye neMethanol.Ayinyibilikiyo emanzini |
Uphawu | Ruifu Chemical |
Into | Iinkcukacha |
Imbonakalo | Umgubo weCrystal oMthubi oMthubi |
Ukuchongwa | Ixesha lokugcinwa kwencopho enkulu kwikhromatogram yesampulu ihambelana naleyo ikwichromatogram efunyenwe ngomgangatho |
Ubunyulu / Indlela yokuHlalutya | >99.0% (HPLC) |
Ilahleko ekomisweni | ≤0.20% (Kwi-105°C ngeeyure eziyi-3.0.) |
Umxholo wamanzi | ≤0.20% |
Intsalela kwi-Ignition | ≤0.20% |
Ukungacoceki Okukodwa | ≤0.50% |
Ukungcola ngokupheleleyo | <1.00% |
Umgangatho woVavanyo | Umgangatho woShishino |
Ukusetyenziswa | abaPhakathi bamayeza;I-API ephakathi (CAS: 163521-08-2) |
Iphakheji: Ibhotile, ingxowa yefoyile yeAluminiyam, 25kg/Igubu lekhadibhodi, okanye ngokwemfuno yomthengi
Imeko yoGcino:Gcina kwizikhongozeli ezivaliweyo kwindawo epholileyo neyomileyo;Khusela ukukhanya kunye nokufuma
I-5-Cyanoindole (i-CAS: i-15861-24-2) isetyenziswa kakhulu kwishishini leyeza njenge-pharmaceutical intermediate.I-5-Cyanoindole ingasetyenziselwa njenge-intermediate ye-API (i-CAS: 163521-08-2), luhlobo lwe-antidepressant ye-serotonergic eyenziwa yiNkampani ye-Merck KGaA.I-API (i-CAS: i-163521-08-2) i-compound yenoveli kunye nobudlelwane obuphezulu kunye nokukhetha kwi-5-hydroxytrptamine (5-HT) umthuthi kunye ne-5-HT (1A) i-receptors, ibonakaliswe kunyango lwe-disorder disorder enkulu ( MDD), inokusetyenziswa njengelinye lamachiza olunye uhlobo lwamachiza adityanisiweyo angenako ukunyamezela izigulana.Njengokhetho lwe-serotonin reuptake inhibitor, (i-CAS: 163521-08-2) inokuthintela i-serotonin ukuba iphinde ingene kwimizimba yeeseli, ngoko ke yenza ukuba ihlale ixesha elide ngaphakathi kwe-synapse.Ngaphezu koko, (i-CAS: i-163521-08-2) inokukhethwa okuphezulu kwe-serotonin-1A receptor, ithatha impembelelo njenge-agonist eyingxenye engakwazi ukulinganisa ukuveliswa kwe-serotonin.Ezi ziphumo zikhokelela ekwandeni kwe-serotonin kwi-synaptic cleft.Esi siphumo sinxulumene nefuthe le-antidepressant yalo kwi-vivo.