I-5-Fluoro-2-Oxindole CAS 56341-41-4 Ubunyulu > 99.0% (LCMS) I-Sunitinib Malate Intermediate Factory

Inkcazelo emfutshane:

Igama leKhemikhali: 5-Fluoro-2-Oxindole

CAS: 56341-41-4

Ubunyulu: >99.0% (LCMS)

Imbonakalo: Umgubo wekristale oKhanyayo oMthubi

Umbindi we-Sunitinib Malate (CAS: 341031-54-7)

Umgangatho ophezulu, iMveliso yoRhwebo

E-Mail: alvin@ruifuchem.com

Thumela i-imeyile kuthi

Iinkcukacha zeMveliso

Iimveliso ezinxulumeneyo

Iithegi zeMveliso

Inkcazo:

I-Shanghai Ruifu Chemical Co., Ltd. ngumenzi ohamba phambili kunye nomthengisi we-5-Fluoro-2-Oxindole (i-CAS: 56341-41-4) enomgangatho ophezulu, imveliso yorhwebo.Wamkelekile kwiodolo.

Iipropati zeMichiza:

Igama leMchiza	5-Fluoro-2-Oxindole
Izithethantonye	5-Fluorooxindole;5-Fluoro-2-indolinone;I-5-Fluoroindolin-2-enye;5-Fluoro-1,3-Dihydro-indol-2-enye
Inombolo yeCAS	56341-41-4
Inombolo yeCAT	RF-PI1543
Ubume beStokhwe	Kwi-Stock, iMveliso yoMveliso ukuya kwiiToni
Ifomula yeemolekyuli	C8H6FNO
Ubunzima beMolekyuli	151.14
Ukuxinana	1.311±0.06 g/cm3
Uphawu	Ruifu Chemical

Iinkcukacha:

Into	Iinkcukacha
Imbonakalo	Umgubo weCrystalline oKhanyayo oMthubi
I-1 H NMR Spectrum	Ukungqinelana Nolwakhiwo
I-LCMS	Ukungqinelana Nolwakhiwo
Ubunyulu / Indlela yokuHlalutya	>99.0% (LCMS)
Indawo yokunyibilika	143.0 ~ 147.0℃
Ilahleko ekomisweni	<0.50%
Ukungcola ngokupheleleyo	<1.00%
Umgangatho woVavanyo	Umgangatho woShishino
Ukusetyenziswa	abaPhakathi bamayeza;I-Sunitinib Malate ePhakathi

Ukupakishwa kunye noGcino:

Iphakheji: Ibhotile, ingxowa yefoyile yeAluminiyam, 25kg/Igubu lekhadibhodi, okanye ngokwemfuno yomthengi.

Imeko yoGcino:Gcina kwizikhongozeli ezivaliweyo kwindawo epholileyo neyomileyo;Khusela ukukhanya kunye nokufuma.

Izinto eziluncedo:

FAQ:

Isicelo:

I-5-Fluoro-2-Oxindole (i-CAS: 56341-41-4) isetyenziswa kakhulu kwishishini lamachiza njengendawo ephakathi yamayeza.I-5-Fluoro-2-Oxindole yindawo ephakathi kwi-synthesis ye-Sunitinib Malate (i-CAS: 341031-54-7).I-Sunitinib Malate luhlobo lwenoveli yomlomo we-anticancer ekujoliswe kuyo ngamachiza amaninzi kwaye yeye-tyrosine kinase inhibitor ene-multi-targeted enegama layo lokurhweba elithi "Suntent".Iphuhliswe ngempumelelo yiNkampani yePfizer kwaye ineempembelelo ezimbini zokulwa nethumba.Ngaphaya koko, lelona chiza lonyango kuphela elinokuhamba ngaphaya kweminyaka emi-2 yokusinda kumhlaza wezintso okwinqanaba eliphezulu kwaye lidlala indima ephambili kwicandelo le-carcinoma kunye ne-gastrointestinal stromal tumor therapeutic areas.Yangena kwimarike ngoFebruwari 2006 eUnited States.Eli chiza yaba lichiza lokuqala elichasene nomhlaza elavunywa yi-US FDA kwaye ngaxeshanye linganyanga izifo ezibini.