I-5,6,7,8-Tetrahydronaphthalene-1-Carboxylic Acid CAS 4242-18-6 Ubunyulu > 99.0% (HPLC) Palonosetron Hydrochloride Umfanekiso oPhakathi oveziweyo

5,6,7,8-Tetrahydronaphthalene-1-Carboxylic Acid CAS 4242-18-6 Ubunyulu > 99.0% (HPLC) Palonosetron Hydrochloride Intermediate

Inkcazelo emfutshane:

Igama: 5,6,7,8-Tetrahydronaphthalene-1-Carboxylic Acid

Izithethantonye: 5,6,7,8-Tetrahydro-1-Naphthalenecarboxylic Acid

CAS: 4242-18-6

Ubunyulu: >99.0% (HPLC)

Imbonakalo: Umgubo weCrystalline oMhlophe okanye ophantse wamhlophe

Umbindi wePalonosetron Hydrochloride CAS 135729-62-3

Qhagamshelana: UGqr. Alvin Huang

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E-Mail: alvin@ruifuchem.com

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Inkcazo:

I-Shanghai Ruifu Chemical Co., Ltd. ngumenzi ohamba phambili kunye nomthengisi we-5,6,7,8-Tetrahydronaphthalene-1-Carboxylic Acid (CAS: 4242-18-6) enomgangatho ophezulu.Sinokubonelela nge-COA, ukuhanjiswa kwehlabathi jikelele, ubuninzi obuncinci kunye nobuninzi obukhoyo.Ukuba unomdla kule mveliso, nceda uthumele ulwazi oluneenkcukacha lubandakanya inombolo ye-CAS, igama lemveliso, ubuninzi kuthi.Please contact: alvin@ruifuchem.com

Iipropati zeMichiza:

Igama leMchiza	I-5,6,7,8-Tetrahydronaphthalene-1-Carboxylic Acid
Izithethantonye	I-5,6,7,8-Tetrahydro-1-Naphthalenecarboxylic Acid;I-5,6,7,8-Tetrahydro-Naphthalene-1-Carboxylic Acid;I-5,6,7,8-Tetrahydro-1-Naphthoic Acid
Ubume beStokhwe	KwiStokhwe, Umthamo weMveliso kwiiToni
Inombolo yeCAS	4242-18-6
Ifomula yeemolekyuli	C11H12O2
Ubunzima beMolekyuli	176.22
Indawo yokunyibilika	148.0 ~ 152.0℃
Indawo yokubilisa	336.8±31.0℃
Ukuxinana	1.184±0.06 g/cm3
Imeko yokuthumela ngenqanawa	Ubushushu be-Ambient
I-COA kunye ne-MSDS	Iyafumaneka
Uphawu	Ruifu Chemical

Iinkcukacha:

Into	Umgangatho Wokuhlola	Iziphumo
Imbonakalo	Umgubo weCrystalline oMhlophe okanye ophantse wamhlophe	Ithotyelwe
Ilahleko ekomisweni	<1.00%	0.67%
Intsalela kwi-Ignition	<0.20%	0.03%
Indawo yokunyibilika	148.0 ~ 152.0℃	149.9 ~ 150.9℃
Ubunyulu (HPLC)	>99.0% (HPLC)	99.9%
Isivavanyi	98.0 ~ 101.0% (Neutralization Titration)	100.9%
I-1 H NMR Spectrum	Ukungqinelana Nolwakhiwo
Ukuqukumbela	Le Mveliso ngokuHlolwa kweZivumelwano kunye noMgangatho woShishino
Usetyenziso oluphambili	Phakathi kwePalonosetron Hydrochloride (CAS: 135729-62-3)

Ukupakishwa kunye noGcino:

Iphakheji: Ibhotile, ingxowa yefoyile yeAluminiyam, 25kg/Igubu lekhadibhodi, okanye ngokwemfuno yomthengi.

Imeko yoGcino:Gcina kwizikhongozeli ezivaliweyo kwindawo yokugcina impahla epholileyo, eyomileyo nengena umoya kude nezinto ezingahambelaniyo.Khusela ukukhanya kunye nokufuma.

Izinto eziluncedo:

Umthamo owaneleyo: Izixhobo ezaneleyo kunye namagcisa

Inkonzo yobuNgcali: Inkonzo enye yokuyeka ukuthenga

Ipakethe ye-OEM: Iphakheji yesiko kunye neleyibhile ekhoyo

Ukuhanjiswa ngokukhawuleza: Ukuba ngaphakathi kwesitokhwe, ukuhanjiswa kweentsuku ezintathu kuqinisekisiwe

Ubonelelo oluzinzileyo: Gcina isitokhwe esifanelekileyo

Inkxaso yobuGcisa: Isisombululo seTekhnoloji siyafumaneka

Inkonzo yesiNtu yoHlanganiso: Isuka kwiigram ukuya kwiikhilos

Umgangatho ophezulu: Kusekwe inkqubo epheleleyo yokuqinisekisa umgangatho

FAQ:

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Isicelo:

I-5,6,7,8-Tetrahydronaphthalene-1-Carboxylic Acid (CAS: 4242-18-6) yindawo ephakathi esetyenziselwa ukulungiswa kwe-agent ye-antiemetic eluncedo yonyango i-Palonosetron Hydrochloride (CAS: 135729-62-3).I-Palonosetron Hydrochloride iyichiza lokuthintela isicaphucaphu kunye nokuhlanza, luhlobo olutsha olukhethiweyo oluphezulu, oluhambelana ne-5-HT3 ye-receptor antagonist enokuthintela i-vomiting reflex center peripheral neurons presynaptic 5-HT.I-receptor excitement ichaphazela ngokuthe ngqo inkqubo ye-nervous central kwi-5-HT.I-impulse receptor excitement eyenziwa yindima ye-vagal afferent nerve emva kommandla, ukuvimbela i-vagus nerve endings emathunjini, ukukhusela iimpawu kwi-5-HT.Indawo ye-receptor trigger zone inokunciphisa izehlo zesicaphucaphu kunye nokuhlanza.Embindini weklinikhi kunyango lwe-emetogenic ebukhali kakhulu ichemotherapy ebangela ukulibaziseka kwesicaphucaphu kunye nokugabha.Ngenxa yempembelelo yayo ephezulu yokunyanga, isiphumo esincinci, isiqingatha sobomi obude (malunga ne-40 h), idosi encinci, njalo njalo, iye yatsala ingqalelo enkulu.