6-Chloro-2-methyl-2H-indazol-5-amine CAS 1893125-36-4 Ucoceko >98.0% (LCMS) Ensitrelvir (S-217622) Intermediate COVID-19
Ubonelelo ngezoRhwebo lwe-Ensitrelvir (S-217622) abaPhakathi:
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2,4,5-Trifluorobenzyl Bromide CAS 157911-56-3
I-Trimethyloxonium Tetrafluoroborate CAS 420-37-1
I-6-Chloro-2-methyl-2H-indazol-5-amine CAS 1893125-36-4
3-(Chloromethyl)-1-methyl-1H-1,2,4-triazole hydrochloride CAS 135206-76-7
1,3,5-Triazine-2,4 (1H,3H)-dione, 3-(1,1-dimethylethyl)-6-(ethylthio)- CAS 1360105-53-8
Igama leMchiza | I-6-Chloro-2-methyl-2H-indazol-5-amine |
Inombolo yeCAS | 1893125-36-4 |
Inombolo yeCAT | RF-PI1506 |
Ubume beStokhwe | Ikhona evenkileni |
Ifomula yeemolekyuli | C8H8ClN3 |
Ubunzima beMolekyuli | 181.62 |
Uphawu | Ruifu Chemical |
Into | Iinkcukacha |
Imbonakalo | I-Brown eKhanyayo ukuya kuMvumbi oLuqilima |
Ubunyulu / Indlela yokuHlalutya | >98.0% (LCMS) |
I-1 H NMR Spectrum | Ukungqinelana Nolwakhiwo |
I-LCMS | Ukungqinelana Nolwakhiwo |
Ilahleko ekomisweni | ≤1.00% |
Ukungcola ngokupheleleyo | <2.00% |
Umgangatho woVavanyo | Umgangatho woShishino |
Ukusetyenziswa | Umbindi we-Ensitrelvir (S-217622), COVID-19 |
Iphakheji: Ibhotile, 25kg / Drum, okanye ngokwemfuno umthengi.
Imeko yoGcino:Gcina kwizikhongozeli ezivaliweyo kwindawo epholileyo neyomileyo;Khusela ukukhanya kunye nokufuma.
I-6-Chloro-2-methyl-2H-indazol-5-amine (i-CAS: 1893125-36-4) iphakathi kwe-Ensitrelvir (S-217622).I-Ensitrelvir nguShionogi & Co. lichiza elisebenza kakhulu lokuthomalalisa iintsholongwane elisebenza kanye njengePfizer's Paxlovid.I-Oral Xocova (Ensitrelvir), enendlela yokusebenza efanayo nePfizer's Paxlovid (Nirmatrelvir+Ritonavir), yohluka ngokuba kufuneka ithathwe kube kanye ngosuku, ngelixa ukusebenza konyango kwe-ensitrelvir kungabonakali kungaphantsi kwePaxlovid.Njengesikhumbuzo, i-Nirmatrelvir isetyenziswa kabini yonke imihla, kunye ne-booster emelwe yi-Ritonavir.I-Ensitrelvir yaba yipilisi yokuqala yasekhaya yaseJapan ukunyanga i-COVID-19, eyesithathu ukuba yamkelwe ngokusemthethweni eJapan;ngoFebruwari 2022.