6-Fluoro-3-Hydroxypyrazine-2-Carbonitrile CAS 356783-31-8 Ubunyulu ≥98.0% (HPLC) Favipiravir Intermediate COVID-19
Umenzi onobunyulu obuPhezulu kunye noMgangatho oZinzile
Ubonelelo ngezoRhwebo lweFavipiravir kunye nabaPhakathi abaNxulumeneyo:
IFavipiravir CAS 259793-96-9
I-2-Aminopropanediamide CAS 62009-47-6
I-Diethyl Aminomalonate Hydrochloride CAS 13433-00-6
3,6-Dichloropyrazine-2-Carbonitrile CAS 356783-16-9
3,6-Difluoropyrazine-2-Carbonitrile CAS 356783-28-3
I-6-Fluoro-3-Hydroxypyrazine-2-Carbonitrile CAS 356783-31-8
I-6-Bromo-3-Hydroxypyrazine-2-Carboxamide CAS 259793-88-9
I-3-Hydroxypyrazine-2-Carboxamide CAS 55321-99-8
Igama leMchiza | I-6-Fluoro-3-Hydroxypyrazine-2-Carbonitrile |
Izithethantonye | 6-Fluoro-3-oxo-3,4-Dihydropyrazine-2-Carbonitrile |
Inombolo yeCAS | 356783-31-8 |
Inombolo yeCAT | RF-API294 |
Ubume beStokhwe | Kwi-Stock, iMveliso yeMveliso ukuya kumakhulu eeKilogram |
Ifomula yeemolekyuli | I-C5H2FN3O |
Ubunzima beMolekyuli | 139.09 |
Uphawu | Ruifu Chemical |
Into | Iinkcukacha |
Imbonakalo | Mthubi oMthubi ukuya kumgubo oMhlophe |
Ukuchongwa | IR, HPLC |
Ukufuma (KF) | ≤1.0% |
Intsalela kwi-Ignition | ≤0.50% |
Ukungacoceki Okukodwa | ≤1.0% |
Ukungcola ngokupheleleyo | ≤2.0% |
Iintsimbi ezinzima | ≤20ppm |
Ubunyulu | ≥98.0% (nge-HPLC) |
Umgangatho woVavanyo | Umgangatho woShishino |
Ukusetyenziswa | Umbindi weFavipiravir (CAS 259793-96-9);I-Antiviral;I-COVID 19 |
Iphakheji: Ibhotile, ingxowa yefoyile yeAluminiyam, igubu lekhadibhodi, 25kg/Igubu, okanye ngokwemfuno yomthengi.
Imeko yoGcino:Gcina kwizikhongozeli ezivaliweyo kwindawo epholileyo neyomileyo;Khusela ekukhanyeni, ukufuma kunye nokuhlaselwa zizinambuzane.
I-6-Fluoro-3-Hydroxypyrazine-2-Carbonitrile (CAS 356783-31-8) nguMphakathi weFavipiravir (CAS 259793-96-9).I-Favipiravir lichiza elitsha le-antiviral ebanzi elijolise kwi-RNA exhomekeke kwi-RNA polymerase (RdRp).IFavipiravir yaveliswa ekupheleni kweminyaka yoo-1990 yinkampani eyathi kamva yathengwa yifem yaseJapan iFujifilm njengenxalenye yotshintsho lwayo ukusuka kwishishini leefoto ukuya kukhathalelo lwempilo.Emva kokuvavanywa ngokuchasene noluhlu lweentsholongwane, ichiza lamkelwa eJapan ngo-2014 ukuze lisetyenziswe ngokukhawuleza ngokuchasene nobhubhane lomkhuhlane okanye ukunyanga iintlobo ezintsha zomkhuhlane.Ngexesha lokuqhambuka kwe-coronavirus entsha, iziphumo zeSigaba soku-I sophononongo lwezonyango lwechiza elapapashwa ngo-Matshi ka-2020 zabonisa ukuba iyeza linokuba nefuthe lokukhawulezisa ukucocwa kwentsholongwane ukudambisa inkqubela-phambili yenyumoniya entsha ye-coronavirus.IFavipiravir inokusetyenziswa kunyango lwezigulane ezine-COVID-19 ezicetyiswa yi-WHO.Yacinywa nguMlawuli Jikelele weZiyobisi waseIndiya (DCGI) kusetyenziso "lwexesha likaxakeka" phakathi kwabaguli be-COVID-19.