I-6-Mercaptopurine 6-MP CAS 50-44-2 Assay 97.0 ~ 102.0% Factory USP Standard
Ubonelelo lwabavelisi, ubunyulu obuphezulu, iMveliso yoRhwebo
Igama leKhemikhali: 6-Mercaptopurine
CAS: 50-44-2
Igama leMchiza | 6-Mercaptopurine |
Izithethantonye | iMercaptopurine;6-MP;6-Mercaptopurine (monohydrate) |
Inombolo yeCAS | 50-44-2 |
Inombolo yeCAT | RF-PI487 |
Ubume beStokhwe | Kwi-Stock, iMveliso yoMveliso ukuya kwiiToni |
Ifomula yeemolekyuli | I-C5H4N4S |
Ubunzima beMolekyuli | 152.18 |
Uphawu | Ruifu Chemical |
Into | Iinkcukacha |
Imbonakalo | Umgubo weCrystalline otyheli |
Isivavanyi | 97.0~102.0% |
Indawo yokunyibilika | ≥300℃ |
Ukungcola okuguquguqukayo kwe-Organic | Yifezekise iMfuneko |
Ilahleko ekomisweni | ≤11.0% |
Intsalela kwi-Ignition | ≤0.20% |
Hypoxanthine | ≤1.0% |
Iintsimbi ezinzima | ≤10ppm |
Umgangatho woVavanyo | I-United States Pharmacopoeia (USP) |
Ukusetyenziswa | API;AbaPhakathi bamayeza |
Iphakheji: Ibhotile, ingxowa yefoyile yeAluminiyam, 25kg/Igubu lekhadibhodi, okanye ngokwemfuno yomthengi.
Imeko yoGcino:Gcina kwizikhongozeli ezivaliweyo kwindawo epholileyo neyomileyo;Khusela ukukhanya kunye nokufuma.
I-6-Mercaptopurine (i-CAS: i-50-44-2) i-agent ye-antileukemic esetyenziswa ngokubanzi kunye ne-immunosuppressive drug inhibits de novo purine synthesis ngokufakwa kwe-thiopurine methyltransferase metabolites kwi-DNA kunye ne-RNA.I-6-Mercaptopurine i-analogue ye-purine esebenza njengomchasi we-endogenous purines kwaye isetyenziswe ngokubanzi njenge-antileukemic agent kunye ne-immunosuppressive drug.I-Mercaptopurine inqanda i-purine nucleotide synthesis kunye ne-metabolism ngokuvimbela i-enzyme ebizwa ngokuba yi-Phosphoribosyl pyrophosphate amidotransferase (PRPP Amidotransferase).I-Mercaptopurine iphazamisa i-nucleotide interconversion kunye ne-glycoprotein synthesis.I-Mercaptopurine, ethengiswa phantsi kwegama le-brand yePurinethol, ngokukodwa isetyenziselwa ukunyanga i-acute lymphocytic leukemia (YONKE), i-myeloid leukemia engapheliyo (CML), isifo sikaCrohn, kunye ne-ulcerative colitis.