6,6-Dimethyl-3-azabicyclo[3.1.0]hexane CAS 943516-54-9 PF-07321332 Boceprevir Eliphakathi
Ubonelelo ngezoRhwebo PF-07321332 Paxlovid abaPhakathi abaNxungupheleyo abanoMgangatho oPhezulu
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(1R,2S,5S)-6,6-Dimethyl-3-azabicyclo[3.1.0]hexane-2-Carboxylic Acid Methyl Ester Hydrochloride 565456-77-1
I-Methyl (S)-2-(Boc-amino)-3-[(S)-2-oxo-3-pyrrolidinyl]propanoate CAS 328086-60-8
6,6-Dimethyl-3-azabicyclo[3.1.0]hexane CAS 943516-54-9
Igama leMchiza | 6,6-Dimethyl-3-azabicyclo [3.1.0] hexane |
Inombolo yeCAS | 943516-54-9 |
Inombolo yeCAT | RF-PI316 |
Ubume beStokhwe | Kwi-Stock, iMveliso yoMveliso ukuya kwiiToni |
Ifomula yeemolekyuli | C7H13N |
Ubunzima beMolekyuli | 111.18 |
Indawo yokubilisa | 135℃ |
Ukuxinana | 0.911 |
Uphawu | Ruifu Chemical |
Into | Iinkcukacha |
Imbonakalo | Ulwelo oluNgaMabala oluNgaMabala |
Ubunyulu | ≥98.0% |
Ukungacoceki Okukodwa | ≤0.50% |
Ukungcola ngokupheleleyo | ≤2.0% |
Iintsimbi ezinzima | ≤20ppm |
Umgangatho woVavanyo | Umgangatho woShishino |
Ukusetyenziswa | Phakathi kwe-PF-07321332 Paxlovid (CAS 2628280-40-8) kunye ne-Boceprevir (CAS 394730-60-0) |
Iphakheji: Ibhotile, ingxowa yefoyile yeAluminiyam, igubu lekhadibhodi, 25kg/Igubu, okanye ngokwemfuno yomthengi.
Imeko yoGcino:Gcina kwizikhongozeli ezivaliweyo kwindawo epholileyo neyomileyo;Khusela ekukhanyeni, ukufuma kunye nokuhlaselwa zizinambuzane.
I-6,6-Dimethyl-3-azabicyclo [3.1.0] i-hexane (i-CAS 943516-54-9) iphakathi kwe-PF-07321332 Paxlovid (CAS 2628280-40-8) kunye ne-Boceprevir (CAS 394730-60-0).I-Pfizer's Paxlovid PF-07321332 lunyango lwe-antiviral lomlomo olujolise kwi-SARS-CoV-2 betacoronavirus ukuthintela i-COVID-19.I-Paxlovid yi-protease inhibitor ebonise umsebenzi onamandla we-vitro antiviral ngokuchasene ne-SARS-CoV-2 kunye nezinye ii-coronavirus, ecebisa ukuba zinokusetyenziswa kunyango lwe-COVID-19, kunye nokusetyenziswa okunokwenzeka ngokuchasene nezoyikiso zentsholongwane kwixesha elizayo, utshilo uPfizer.I-Boceprevir (EBP 520) inamandla, ikhetha kakhulu, i-oral bioavailable HCV NS3 protease inhibitor ene-Ki ye-14 nM kuzo zombini i-enzyme assay kunye ne-EC90 ye-350 nM kwi-cell-based replicon assay.I-Boceprevir inqanda umsebenzi we-SARS-CoV-2 3CLpro.