7-Bromopyrrolo[2,1-f][1,2,4]triazin-4-amine CAS 937046-98-5 Remdesivir Intermediate COVID-19

Inkcazelo emfutshane:

Igama leMichiza: 7-Bromopyrrolo[2,1-f][1,2,4]triazin-4-amine

CAS: 937046-98-5

Imbonakalo: Umgubo oMthubi oKhanyayo

Ubunyulu: ≥97.0%

Umbindi we-Remdesivir (CAS 1809249-37-3) COVID-19

Umgangatho ophezulu, iMveliso yoRhwebo

Inquiry: alvin@ruifuchem.com

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Iinkcukacha zeMveliso

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Iithegi zeMveliso

Inkcazo:

Ubonelelo ngezoRhwebo loMvelisi i-Remdesivir kunye nabaPhakathi abaNxulumeneyo nabanoMgangatho oPhezulu
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Iipropati zeMichiza:

Igama leMchiza	7-Bromopyrrolo[2,1-f][1,2,4]triazin-4-amine
Izithethantonye	4-Amino-7-bromopyrrolo[2,1-f][1,2,4]triazine;Ukungacoceki kwe-Remdesivir 2
Inombolo yeCAS	937046-98-5
Inombolo yeCAT	RF-PI305
Ubume beStokhwe	Kwi-Stock, iMveliso yeMveliso ukuya kumakhulu eeKilogram
Ifomula yeemolekyuli	I-C6H5BrN4
Ubunzima beMolekyuli	213.04
Uphawu	Ruifu Chemical

Iinkcukacha:

Into	Iinkcukacha
Imbonakalo	Umgubo oMthubi oKhanya
I-Infrared Spectrum	Iyahambelana neSakhiwo
NMR	Iyahambelana neSakhiwo
Ubunyulu	≥97.0%
Ilahleko ekomisweni	≤1.0
Ukungacoceki Okukodwa	≤1.0%
Iintsimbi ezinzima	≤20ppm
Umgangatho woVavanyo	Umgangatho woShishino
Ukusetyenziswa	Umbindi we-Remdesivir (CAS 1809249-37-3)

Ukupakishwa kunye noGcino:

Iphakheji: Ibhotile, ingxowa yefoyile yeAluminiyam, igubu lekhadibhodi, 25kg/Igubu, okanye ngokwemfuno yomthengi.

Imeko yoGcino:Gcina kwizikhongozeli ezivaliweyo kwindawo epholileyo neyomileyo;Khusela ekukhanyeni, ukufuma kunye nokuhlaselwa zizinambuzane.

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Isicelo:

I-7-Bromopyrrolo[2,1-f][1,2,4] triazin-4-amine (CAS 937046-98-5) nguMphakathi we-Remdesivir (CAS 1809249-37-3).I-Remdesivir lichiza le-antiviral elisebenza ngokuchasene ne-acute acute breathing syndrome 2 (SARS-CoV-2).I-Remdesivir (ekwabizwa ngokuba yiVeklury okanye i-GS-5734) yi-SARS-CoV-2 nucleotide analog RNA polymerase inhibitor eboniswe kubantu abadala nakwizigulana zabantwana (abaneminyaka eyi-12 ubudala nangaphezulu kwaye banobunzima obungama-40 kg) kunyango lwesifo se-coronavirus ngo-2019. (COVID-19) ifuna ukulaliswa esibhedlele.I-Remdesivir kufuneka ilawulwe kuphela esibhedlele okanye kwindawo yokhathalelo lwempilo ekwaziyo ukunika ukhathalelo oluqatha oluthelekiswa nokhathalelo lwasesibhedlele.I-Remdesivir yaqala yaphuhliswa njenge-anti-viral ngokuchasene nentsholongwane ye-Ebola, kodwa ukusukela oko ibonakaliswe ukuba ithobe imithwalo yentsholongwane enani leentsholongwane ze-RNA ezibandakanya i-respiratory syncytial virus (RSV) kunye ne-β-coronaviruses ezifana ne-SARS-CoV, MERS-CoV, kunye unobangela we-COVID-19, SARS-CoV-2.