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7-Chloro-1,2,3,4-tetrahydrobenzo[b]azepin-5-enye CAS 160129-45-3 Tolvaptan Intermediate Featured Image
  • 7-Chloro-1,2,3,4-tetrahydrobenzo[b]azepin-5-enye CAS 160129-45-3 Tolvaptan Intermediate

7-Chloro-1,2,3,4-tetrahydrobenzo[b]azepin-5-enye CAS 160129-45-3 Tolvaptan Intermediate

Inkcazelo emfutshane:

Igama: 7-Chloro-1,2,3,4-tetrahydrobenzo[b]azepin-5-enye

CAS: 160129-45-3

Ubunyulu: ≥99.0% (HPLC)

Imbonakalo: Buhlaza obuKhanyayo ukuya kumgubo oMthubi oKhanyayo

Phakathi kweTolvaptan (CAS 150683-30-0) yonyango lwe-Hyponatremia

Umgangatho ophezulu, iMveliso yoRhwebo

Inquiry: alvin@ruifuchem.com

 


Iinkcukacha zeMveliso

Iimveliso ezinxulumeneyo

Iithegi zeMveliso

Inkcazo:

Ubonelelo loMvelisi, uMgangatho oPhezulu, iMveliso yoRhwebo
I-Tolvaptan kunye nabaPhakathi abaNxulumeneyo:
Tolvaptan CAS 150683-30-0
7-Chloro-1,2,3,4-tetrahydrobenzo[b]azepin-5-enye CAS 160129-45-3
o-Toluoyl Chloride CAS 933-88-0
I-4-Amino-2-Methylbenzoic Acid CAS 2486-75-1
I-2-Methyl-4-Nitrobenzoic Acid CAS 1975-51-5

Iipropati zeMichiza:

Igama leMchiza 7-Chloro-1,2,3,4-tetrahydrobenzo[b]azepin-5-enye
Izithethantonye I-7-Chloro-1,2,3,4-tetrahydro-5H-1-benzazepin-5-enye;7-Chloro-3,4-dihydro-1H-benzo[b]azepin-5(2H)-enye
Inombolo yeCAS 160129-45-3
Inombolo yeCAT RF-PI395
Ubume beStokhwe Kwi-Stock, iMveliso yoMveliso ukuya kwiiToni
Ifomula yeemolekyuli C10H10ClNO
Ubunzima beMolekyuli 195.65
Indawo yokunyibilika 103.0 ukuba 107.0℃
Ukunyibilika Inyibilika kwiMethanol
Uphawu Ruifu Chemical

Iinkcukacha:

Into Iinkcukacha
Imbonakalo UBuhlaza obuKhanyayo ukuya kumgubo oMthubi oKhanyayo
Iindlela zokuchongwa NMR, HPLC
Ubunyulu / Indlela yokuHlalutya ≥99.0% (HPLC)
Ilahleko ekomisweni ≤1.0%
Intsalela kwi-Ignition ≤0.50%
Nakuphi na Ukungacoceki Okukodwa ≤0.50%
Ukungcola ngokupheleleyo ≤1.0%
Umgangatho woVavanyo Umgangatho woShishino
Ukusetyenziswa Phakathi kweTolvaptan (CAS 150683-30-0), unyango lwe-Hyponatremia

Ukupakishwa kunye noGcino:

Iphakheji: Ibhotile, ingxowa yefoyile yeAluminiyam, 25kg/Igubu lekhadibhodi, okanye ngokwemfuno yomthengi.

Imeko yoGcino:Gcina kwizikhongozeli ezivaliweyo kwindawo epholileyo neyomileyo;Khusela ukukhanya kunye nokufuma.

Izinto eziluncedo:

1

FAQ:

Isicelo:

I-7-Chloro-1,2,3,4-tetrahydrobenzo [b] i-azepin-5-enye (i-CAS 160129-45-3) iphakathi kwi-synthesis ye-Tolvaptan (CAS 150683-30-0).I-Tolvaptan yinto ekhethiweyo, ekhuphisanayo ngomlomo esebenzayo i-nonpeptide arginine vasopressin V2 i-receptor antagonist kunye ne-IC50 ye-1.28µM yokuthintela i-AVP-induced platelet aggregation.I-Tolvaptan isetyenziselwa ukunyanga i-hyponatremia ehambelana nokungaphumeleli kwentliziyo, i-cirrhosis, kunye ne-syndrome ye-antidiuretic hormone engafanelekanga.I-Tolvaptan ikwakwizilingo zeklinikhi ezikhawulezayo zesifo sezintso ze-polycystic.Unyango ngeTolvaptan lubangela ukuthotywa kobunzima bomzimba obukhawulezayo nobuzinzileyo ngaxeshanye kunye nokunyuka kokuphuma komchamo, kuphucula kunye/okanye kulungelelanisa i-serum sodium kwizigulane ze-hyponatremic, kunciphisa iimpawu kunye neempawu zokuxinana kunye nokwandisa ukoma.

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