I-7-Ethyl-10-Hydroxycamptothecin CAS 86639-52-3 Irinotecan Hydrochloride Ucoceko oluPhakathi oluPhakathi

Inkcazelo emfutshane:

Igama leMichiza: 7-Ethyl-10-Hydroxycamptothecin (SN-38)

CAS: 86639-52-3

INkangeleko: Umgubo weeCrystals eziMthubi oKhanyayo

Uvavanyo: ≥98.0% (HPLC)

Phakathi kwe-Irinotecan Hydrochloride (CAS: 100286-90-6), i-DNA Topoisomerase I Inhibitor

Umgangatho ophezulu, iMveliso yoRhwebo

Inquiry: alvin@ruifuchem.com


Iinkcukacha zeMveliso

Iimveliso ezinxulumeneyo

Iithegi zeMveliso

Inkcazo:

Iipropati zeMichiza:

Igama leMchiza 7-Ethyl-10-Hydroxycamptothecin
Izithethantonye SN-38
Inombolo yeCAS 86639-52-3
Inombolo yeCAT RF-PI242
Ubume beStokhwe Kwi-Stock, iMveliso yoMveliso ukuya kwiiToni
Ifomula yeemolekyuli I-C22H20N2O5
Ubunzima beMolekyuli 392.41
Uphawu Ruifu Chemical

Iinkcukacha:

Into Iinkcukacha
Imbonakalo Umgubo Wamakristale aMthubi oKhanyayo
Ukuchongwa (IR, UV) (1) Imitha ye-ultraviolet yokufunxa i-spectrum ihambelana neemfuno
(2) I-infrared ray yokufunxa i-spectrum ehambelanayo kunye ne-reference standard spectrum iya kuhambelana novavanyo oluvunyiweyo.
Indawo yokunyibilika 228.0~235.0℃
Izinto ezinxulumeneyo ≤1.5%
I-10-Hydroxycamptothecin ≤0.30%
7-Cthylcamptothecin ≤0.70%
Ubuninzi bokungcola okungaziwayo ≤0.50%
Ilahleko ekomisweni ≤1.0%
Iintsimbi ezinzima ≤10ppm
Intsalela kwi-Ignition ≤0.10%
Ukucaca kwesisombululo Cacileyo
Isivavanyi ≥98.0% (HPLC)
Umgangatho woVavanyo Umgangatho woShishino
Ukusetyenziswa I-Pharmaceutical Intermediate ye-Irinotecan

Ukupakishwa kunye noGcino:

Iphakheji: Ibhotile, ingxowa yefoyile yeAluminiyam, igubu lekhadibhodi, 25kg/Igubu, okanye ngokwemfuno yomthengi.

Imeko yoGcino:Gcina kwizikhongozeli ezivaliweyo kwindawo epholileyo neyomileyo;Khusela ekukhanyeni, ukufuma kunye nokuhlaselwa zizinambuzane.

Izinto eziluncedo:

1

FAQ:

Isicelo:

I-Shanghai Ruifu Chemical Co., Ltd. ngumenzi ohamba phambili kunye nomthengisi we-7-Ethyl-10-Hydroxycamptothecin (i-CAS: 86639-52-3) enomgangatho ophezulu.I-7-Ethyl-10-Hydroxycamptothecin (i-CAS: 86639-52-3) i-metabolite esebenzayo ye-Topoisomerase I inhibitor Irinotecan.I-SN-38 (NK012) inqanda i-DNA kunye ne-RNA synthesis kunye ne-IC50s of 0.077 kunye 1.3 μM, ngokulandelelanayo.I-7-Ethyl-10-Hydroxycamptothecin (SN-38), i-metabolite esebenzayo ye-Irinotecan, i-semisynthetic derivative ye-camptothecin, i-alkaloid esekelwe kwi-quinoline efumaneka kwi-bark ye-Chinese camptotheca tree kunye ne-Asian nothapodytes tree.Nangona i-7-Ethyl-10-Hydroxycamptothecin ifikelela kumaxesha angama-1,000 anamandla ngaphezu kwe-Irinotecan, ayizange iguqulwe ibe ngumviwa weziyobisi osebenzayo ngenxa yokuba ayinakunyibilika.Kungoku nje iphantsi kolingo lwezonyango zidityaniswe nezinye iinxalenye ezinokuthi ekugqibeleni zivumeleke ukuba zisebenze njengechiza le-antineoplastic.

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