I-7-Ethyl-10-Hydroxycamptothecin CAS 86639-52-3 Irinotecan Hydrochloride Ucoceko oluPhakathi oluPhakathi
Ubonelelo lwabavelisi be-Irinotecan kunye nabaPhakathi abaNxulumeneyo:
Irinotecan Hydrochloride CAS: 100286-90-6
I-Irinotecan Isiseko sasimahla seCAS: 97682-44-5
Irinotecan Hydrochloride Trihydrate CAS: 136572-09-3
I-7-Ethyl-10-Hydroxycamptothecin CAS: 86639-52-3
I-1-Chlorocarbonyl-4-Piperidinopiperidine Hydrochloride CAS: 143254-82-4
| Igama leMchiza | 7-Ethyl-10-Hydroxycamptothecin |
| Izithethantonye | SN-38 |
| Inombolo yeCAS | 86639-52-3 |
| Inombolo yeCAT | RF-PI242 |
| Ubume beStokhwe | Kwi-Stock, iMveliso yoMveliso ukuya kwiiToni |
| Ifomula yeemolekyuli | I-C22H20N2O5 |
| Ubunzima beMolekyuli | 392.41 |
| Uphawu | Ruifu Chemical |
| Into | Iinkcukacha |
| Imbonakalo | Umgubo Wamakristale aMthubi oKhanyayo |
| Ukuchongwa (IR, UV) | (1) Imitha ye-ultraviolet yokufunxa i-spectrum ihambelana neemfuno (2) I-infrared ray yokufunxa i-spectrum ehambelanayo kunye ne-reference standard spectrum iya kuhambelana novavanyo oluvunyiweyo. |
| Indawo yokunyibilika | 228.0~235.0℃ |
| Izinto ezinxulumeneyo | ≤1.5% |
| I-10-Hydroxycamptothecin | ≤0.30% |
| 7-Cthylcamptothecin | ≤0.70% |
| Ubuninzi bokungcola okungaziwayo | ≤0.50% |
| Ilahleko ekomisweni | ≤1.0% |
| Iintsimbi ezinzima | ≤10ppm |
| Intsalela kwi-Ignition | ≤0.10% |
| Ukucaca kwesisombululo | Cacileyo |
| Isivavanyi | ≥98.0% (HPLC) |
| Umgangatho woVavanyo | Umgangatho woShishino |
| Ukusetyenziswa | I-Pharmaceutical Intermediate ye-Irinotecan |
Iphakheji: Ibhotile, ingxowa yefoyile yeAluminiyam, igubu lekhadibhodi, 25kg/Igubu, okanye ngokwemfuno yomthengi.
Imeko yoGcino:Gcina kwizikhongozeli ezivaliweyo kwindawo epholileyo neyomileyo;Khusela ekukhanyeni, ukufuma kunye nokuhlaselwa zizinambuzane.
I-Shanghai Ruifu Chemical Co., Ltd. ngumenzi ohamba phambili kunye nomthengisi we-7-Ethyl-10-Hydroxycamptothecin (i-CAS: 86639-52-3) enomgangatho ophezulu.I-7-Ethyl-10-Hydroxycamptothecin (i-CAS: 86639-52-3) i-metabolite esebenzayo ye-Topoisomerase I inhibitor Irinotecan.I-SN-38 (NK012) inqanda i-DNA kunye ne-RNA synthesis kunye ne-IC50s of 0.077 kunye 1.3 μM, ngokulandelelanayo.I-7-Ethyl-10-Hydroxycamptothecin (SN-38), i-metabolite esebenzayo ye-Irinotecan, i-semisynthetic derivative ye-camptothecin, i-alkaloid esekelwe kwi-quinoline efumaneka kwi-bark ye-Chinese camptotheca tree kunye ne-Asian nothapodytes tree.Nangona i-7-Ethyl-10-Hydroxycamptothecin ifikelela kumaxesha angama-1,000 anamandla ngaphezu kwe-Irinotecan, ayizange iguqulwe ibe ngumviwa weziyobisi osebenzayo ngenxa yokuba ayinakunyibilika.Kungoku nje iphantsi kolingo lwezonyango zidityaniswe nezinye iinxalenye ezinokuthi ekugqibeleni zivumeleke ukuba zisebenze njengechiza le-antineoplastic.
