I-Ac-HMBA-Linker CAS 15561-46-3 4-(Acetoxymethyl)benzoic Acid Purity>98.0% (HPLC)
I-Shanghai Ruifu Chemical Co., Ltd. ngumenzi ohamba phambili we-4- (Acetoxymethyl) benzoic Acid (Ac-HMBA-Linker) (i-CAS: 15561-46-3) enomgangatho ophezulu.I-Ruifu Chemical ibonelela ngothotho lwamakhonkco okudibanisa kwisigaba esiqinileyo.I-Ruifu inokubonelela ngenkonzo yehlabathi jikelele, ixabiso elikhuphisanayo, amanani amancinci kunye nesixa esikhulu esikhoyo.Thenga i-Ac-HMBA-Linker,Please contact: alvin@ruifuchem.com
Igama leMchiza | 4-(Acetoxymethyl) benzoic Acid |
Izithethantonye | I-Ac-HMBA-Linker;4-[(Acetyloxy)methyl]benzoic Acid;I-4-Acetoxymethylbenzoic Acid |
Ubume beStokhwe | Ikhona evenkileni |
Inombolo yeCAS | 15561-46-3 |
Ifomula yeemolekyuli | C10H10O4 |
Ubunzima beMolekyuli | 194.18 g/mol |
Indawo yokunyibilika | 123.0 ~ 124.0℃ |
Ukuxinana | 1.254±0.06 g/cm3 |
Ugcino Temp. | Indawo epholileyo neyomileyo (2~8℃) |
I-COA kunye ne-MSDS | Iyafumaneka |
Udidi | Izinxulumanisi zeSigaba esiSolid iSnthesis |
Uphawu | Ruifu Chemical |
Izinto | ImiGangatho yokuHlola | Iziphumo |
Imbonakalo | Mhlophe ukuya kwi-Off-White Powder | Iyahambelana |
Ubunyulu / Indlela yokuHlalutya | >98.0% (HPLC) | 99.59% |
I-1 H NMR Spectrum | Ngokungqinelana noLwakhiwo | Iyahambelana |
Ukuqukumbela | Imveliso ivavanyiwe kwaye iyahambelana neenkcukacha |
Umqulu:Ibhotile yeFluoride, ibhotile yeglasi, okanye ngokwemfuno yomthengi.
Imeko yoGcino:Gcina kwizikhongozeli ezivaliweyo kwindawo yokugcina impahla epholileyo neyomileyo (2~8℃) kude nezinto ezingahambelaniyo.Khusela ukukhanya kunye nokufuma.
Ukuhambisa ngenqanawe:Zisa kwihlabathi liphela ngeFedEx / DHL Express.Ukubonelela ngokukhawuleza nangokuthembekileyo.
Ukuthenga njani?Nceda uqhagamshelaneDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
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UmgangathoIsiqinisekiso?Inkqubo yokulawula umgangatho ongqongqo.Izixhobo zobuchwephesha zokuhlalutya ziquka i-NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, njl.
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MOQ?Akukho MOQ.Umyalelo omncinci wamkelekile.
Ixesha lokuzisa? Ukuba ngaphakathi kwesitokhwe, ukuhanjiswa kweentsuku ezintathu kuqinisekisiwe.
Ezothutho?Nge-Express (FedEx, DHL), ngoMoya, ngoLwandle.
Amaxwebhu?Emva kwenkonzo yokuthengisa: I-COA, i-MOA, i-ROS, i-MSDS, njl.
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Immimiselo yokuhlawula?I-invoyisi yeProforma iya kuthunyelwa kuqala emva kokuqinisekiswa kwe-odolo, efakwe kwiinkcukacha zethu zebhanki.Intlawulo nge-T / T (i-Telex Transfer), i-PayPal, i-Western Union, njl.
I-4-(i-Acetoxymethyl) i-benzoic Acid (i-Ac-HMBA-Linker) (i-CAS: i-15561-46-3), izixhumanisi ze-synthesis yesigaba esiqinileyo.Isiseko se-labile ye-4-hydroxymethylbenzoic acid (HMBA) ikhonkco, isuswe ngokufanelekileyo kwi-pH = 10.Ikhonkco ye-HMBA yaboniswa ukuba izinzile kwiimeko ezifunekayo kwi-native chemical ligation, ukuguqulwa okulandelayo kunye nokucocwa kokugqibela.I-benzyl ester, eyenza i-HMBA ikhonkco kunye ne-amino acid yokuqala, izinzile kwi-piperidine, esetyenziselwa ukususwa kweqela le-Fmoc, okwenza uxhulumaniso lusebenze kwi-chemical elongation ye-peptide sequence kunye nezicwangciso ze-Fmoc.Uluhlu olukhulu lwe-C-terminally modified peptides lufunyenwe nge-nucleophilic cleavage ye-ester bond kwisigaba esiqinileyo se-peptide esters ye-4-hydroxymethyl benzamide (HMBA).Iindlela eziphuhlisiwe zibonelela ngeepeptides, i-C-terminally functionalized njenge-esters, i-amides kunye ne-thioesters, ngokucoceka okuphezulu ngokuthe ngqo kwi-resin kwisinyathelo esisodwa sokusabela.I-4-hydroxymethylbenzoic acid linkage, eyayicatshulwe yi-ammonolysis kwi-isopropanol, yanika imodeli ye-peptide 1 kwisivuno esihle ngokubanzi (53% kubandakanywa nokusebenza).