I-Acesulfame K CAS 55589-62-3 Acesulfame Potassium Purity >99.0% (HPLC)
I-Shanghai Ruifu Chemical Co., Ltd. ngumenzi ohamba phambili we-Acesulfame K (i-Acesulfame Potassium) (i-CAS: 55589-62-3) enomgangatho ophezulu, i-sweetener yokutya.I-Ruifu inokubonelela ngenkonzo yehlabathi jikelele, ixabiso elikhuphisanayo, amanani amancinci kunye nesixa esikhulu esikhoyo.Thenga iAcesulfame K,Please contact: alvin@ruifuchem.com
| Igama leMchiza | Acesulfame K |
| Izithethantonye | iAcesulfame Potassium;iTyuwa yeAcesulfame yePotassium;6-Methyl-1,2,3-Oxathiazin-4 (3H) -enye 2,2-Dioxide Potassium Ityuwa;I-Potassium 6-Methyl-1,2,3-Oxathiazin-4 (3H) -enye 2,2-Dioxide;Otizon;iPotassium Acesulfame;Sunett;Sunnett;Imnandi enye;I-ADI |
| Ubume beStokhwe | Kwi-Stock, Kwenziwa uRhwebo |
| Inombolo yeCAS | 55589-62-3 |
| Ifomula yeemolekyuli | I-C4H4KNO4S |
| Ubunzima beMolekyuli | 201.24 g/mol |
| Indawo yokunyibilika | 229.0~232.0℃(dec.) |
| Inovakalelo | Ukungenwa kukufuma |
| Ukunyibilika kwamanzi | Inyibilika Emanzini, Phantse Ukungafihli |
| Ivumba | Ayinavumba neTaste eSweet |
| Ugcino Temp. | Indawo epholileyo neyomileyo (2~8℃, Kude nokufuma) |
| I-COA kunye ne-MSDS | Iyafumaneka |
| Uphawu | Ruifu Chemical |
| Izinto | ImiGangatho yokuHlola | Iziphumo |
| Imbonakalo | Umgubo weCrystalline oMhlophe | Iyahambelana |
| Isiqulatho sokuVavanya | 99.0 ~ 101.0% (Ibalwe kwiSisekelo esomileyo) | 99.63% |
| Indawo yokunyibilika | 229.0 ~ 232.0℃ | Iyahambelana |
| Ilahleko ekomisweni | <1.00% | 0.09% |
| I-Sulfate Ash | <0.50% | Iyahambelana |
| Ixabiso le-pH (1 kwi-100 isisombululo) | 5.5~7.5 | 6.65 |
| Potassium | 17.0 ~ 21.0% | Iyahambelana |
| Ukungcola kwezinto eziphilayo | ≤20ppm | Iyahambelana |
| Ukungcola A | ≤0.125% | Iyahambelana |
| Ukungcola B | ≤20ppm | Iyahambelana |
| Iintsimbi ezinzima (Pb) | ≤10ppm | <5ppm |
| I-Fluoride | ≤3ppm | Iyahambelana |
| Arsenic | ≤3ppm | Iyahambelana |
| Inkokeli | ≤1ppm | Iyahambelana |
| Selenium | ≤10ppm | Iyahambelana |
| I-Infrared Spectrum | Iyahambelana neSakhiwo | Iyahambelana |
| I-1 H NMR Spectrum | Iyahambelana neSakhiwo | Iyahambelana |
| Ukuqukumbela | Imveliso ivavanyiwe kwaye iyahambelana neenkcukacha | |
Umqulu:Ibhotile, ingxowa yefoyile yeAluminiyam, 25kg/Igubu lekhadibhodi, okanye ngokwemfuno yomthengi.
Imeko yoGcino:Gcina kwisitya esivaliweyo.Gcina kwindawo epholileyo, eyomileyo (2~8℃) kunye nendawo yokugcina impahla engenamoya kude nezinto ezingahambelaniyo.Khusela ukukhanya kunye nokufuma.
Ukuhambisa ngenqanawe:Zisa kwihlabathi liphela ngomoya, ngeFedEx / DHL Express.Ukubonelela ngokukhawuleza nangokuthembekileyo.
INGCACISO
I-Acesulfame Potassium iqulethe i-NLT 99.0% kunye ne-NMT 101.0% ye-C4H4NO4SK, ibalwe ngokomisiweyo.
UKUCHAZA
• A. UKUFUNWA KWE-IFRARED <197K>
• B. IIMVAVANYO ZOKUCHAZA NGOKUBANZI, iPotassium <191>
Isisombululo sesampuli: 100 mg / mL
Indlela yolwamkelo: Iyahlangabezana neemfuno
UVAVANYO
• INKQUBO
Isampulu: 150 mg
Inkqubo ye-Titrimetric (Jonga i-Titrimetry <541>)
Imowudi: Ukubhalwa ngokuthe ngqo
I-Titrant: 0.1 N i-perchloric acid VS
Akunanto: 50mL ye-acetic acid yeglacial
Ukubonwa kwendawo yokugqibela: I-Potentiometric
Uhlalutyo: Nciba iSampulu kwi-50 mL ye-acetic acid ekhenkcezayo.
I-Titrate nge-0.1 N perchloric acid VS.Yenza isigqibo esingenanto.
Bala ipesenti ye-acesulfame potassium (C4H4NO4SK) kwiSampuli:
Isiphumo = [(V − B) × N × F × 100]/W
V = umthamo we-titrant osetyenziswe yiSampuli (mL)
B = umthamo we-titrant osetyenziswe yi-Gank (mL)
N = ukuqheleka okuqhelekileyo (mEq/mL)
F = i-equivalency factor, i-201.2 mg / mEq
W = ubunzima beSampuli (mg)
Indlela yokwamkela: 99.0% -101.0% kwisiseko esomileyo
UBUNGCOLA
• UMDA WEFLUORIDE
[QAPHELA-Sebenzisa izinto zeplastiki kulo lonke olu vavanyo.]
Isisombululo A: Dissolve 210 g ye-citric acid monohydrate kwi-400 mL yamanzi.Lungisa nge-ammonia egxininisiweyo kwi-pH ye-7.0, kwaye uhlambulule ngamanzi kwi-1000 mL.
Isisombululo B: 132 mg/mL ye-dibasic ammonium phosphate
Isisombululo C: Ukunqunyanyiswa kwe-292 g ye-edetic acid kwi-500 mL yamanzi, yongeza i-200 mL ye-ammonium hydroxide, ulungelelanise ne-ammonium hydroxide kwi-pH phakathi kwe-6 kunye ne-7, kwaye udibanise ngamanzi ukwenza i-1000 mL.
Isisombululo se-Buffer: Hlanganisa umthamo olinganayo weSisombululo A, Isisombululo B kunye neSisombululo C, kwaye ulungelelanise ne-ammonium hydroxide kwi-pH ye-7.5.
Isisombululo sesitokhwe esisemgangathweni: Ubunzima be-0.442 g ye-sodium fluoride, eyomisiwe ngaphambili kwi-300 ° ye-12 h, kwi-flask ye-volumetric 1-L, kwaye ihlambulule ngamanzi ukuya kwivolumu.Gcina isisombululo kwisitya seplastiki esivaliweyo.Ngokukhawuleza ngaphambi kokusetyenziswa, ipayipi ye-5 mL yesi sisombululo kwi-flask ye-volumetric 100-mL, kwaye uhlambulule ngamanzi ukuya kumthamo.I-mL nganye yesi sinyibiliko iqulethe i-10µg ye-ion ye-fluoride.
Isisombululo esisemgangathweni A: Xuba i-0.5 mL yesisombululo sesitokhwe esisemgangathweni kunye ne-15.0 mL yesisombululo se-Buffer, kwaye uhlambulule ngamanzi kwi-50mL.
Isisombululo esisemgangathweni B: Xuba i-1.0 mL yesisombululo sesitokhwe esisemgangathweni kunye ne-15.0 mL yesisombululo se-Buffer, kwaye uhlambulule ngamanzi kwi-50mL.
Isisombululo esisemgangathweni C: Xuba i-1.5 mL yesisombululo se-Standard stock kunye ne-15.0 mL yesisombululo se-Buffer, kwaye uhlambulule ngamanzi kwi-50mL.
Isisombululo esisemgangathweni D: Xuba i-3.0 mL yesisombululo sesitokhwe esisemgangathweni kunye ne-15.0 mL yesisombululo se-Buffer, kwaye uhlambulule ngamanzi kwi-50mL.
Isampuli yesisombululo: Kwi-50-mL ye-volumetric flask yongeza i-3 g ye-Acesulfame Potassium.Ukunyibilikisa emanzini, yongeza i-15.0 mL yesisombululo se-Buffer, kwaye uhlambulule ngamanzi ukuya kwivolumu.
Uhlalutyo
Iisampulu: Isisombululo esisemgangathweni A, isisombululo esisemgangathweni B, isisombululo esisemgangathweni C, isisombululo esisemgangathweni D, kunye nesisombululo seSampuli
Ngokuhambelanayo ukulinganisa amandla (jonga i-Titrimetry <541>) kwi-mV, ye-Standard solutions kunye ne-Sample solution, kunye ne-pH meter efanelekileyo exhotyiswe nge-electrode ye-fluoride-specifiion kunye ne-silver-silver chloride reference electrode.Xa uthatha imilinganiselo, dlulisela isisombululo kwi-beaker ye-25-mL, kwaye ucwilise i-electrodes.Faka ibha yokuvuselela egqunywe ngepolytef kwibeaker, beka ibhekha kwisivusi-magnethi esinomphezulu ogqunyiweyo kwaye uvumele ukushukuma de ulungelelwaniso lufikeleleke (1-2 min).Pula, kwaye womise i-electrode phakathi kwemilinganiselo, unakekele ukuba ungakhuhli ikristale kwi-electrode ye-ion ye-fluoride.Ukulinganisa amandla esisombululo soMgangatho ngamnye, kwaye wenze isicwangciso soxinaniso lwefluoride, kwi-µg/mL, ngokuthelekisa nokubanakho, kwi-mV, kwiphepha le-semilogarithmic.Ukulinganisa amandla esisombululo seSampuli, kwaye umisele ugxininiso lwefluoride ukusuka kwigophe elisemgangathweni, kwiµg/mL.
Bala umxholo, kwi-ppm, wefluoride kwinxalenye yeAcesulfame Potassium ethathiweyo:
Isiphumo = (V × C/W)
V = umthamo weSampuli yesisombululo (mL)
C = ukuxinwa kwe-fluoride kwisisombululo seSampuli, ukusuka kwigophe eliqhelekileyo (mg/mL)
W = ubunzima beAcesulfame Potassium ethathiweyo ukulungiselela isisombululo seSampuli (g)
Indlela yolwamkelo: NMT 3 ppm
• IIMETALI EZINZIMA, Indlela I <231>: NMT 10 ppm
• UBUNCUNGULO WEKHROMATOGRAPHIC
Isisombululo A: 3.3 mg / mL ye-tetrabutylammonium hydrogen sulfate
Isigaba esiphathwayo: I-Acetonitrile kunye nesisombululo A (2:3)
Isisombululo sokufaneleka kwenkqubo: 2 µg/mL nganye ye-USP Acesulfame Potassium RS kunye ne-ethylparaben
Isisombululo esisemgangathweni: 0.2 µg/mL ye-USP Acesulfame Potassium RS
Isisombululo sesampuli: 10 mg / mL
Inkqubo yeChromatographic
(Jonga iChromatography <621>, Ukufaneleka kweNkqubo.)
Indlela: LC
Umtshina: UV 227 nm
Ikholomu: 4.6-mm × 25-cm;5-µm ukupakisha i-L1
Izinga lokuhamba: 1 mL / min
Ubungakanani betofu: 20 µL
Ukufaneleka kwenkqubo
Isampulu: Isisombululo sokufaneleka kwenkqubo
Iimfuno zokufaneleka
Isisombululo: I-NLT 2 phakathi kwe-acesulfame potassium kunye ne-ethylparaben
Uhlalutyo
Iisampulu: Isisombululo esisemgangathweni kunye nesisombululo seSampuli
Rekhoda iichromatograms zexesha lokuqhuba i-NLT 3 amaxesha okugcinwa kwe-acesulfame potassium peak, kwaye ulinganise iimpendulo zengingqi zeendawo eziphakamileyo.
Iinqobo zokwamkelwa: Ukuphendula kwanoma yiyiphi incopho ngexesha lokugcinwa ngaphandle kwe-acesulfame potassium ukusuka kwiSampuli isisombululo asidluli impendulo ye-acesulfame potassium peak ukusuka kwisisombululo esiPhambili (0.002%).
IIMVAVANYO EZITHILE
• I-AIDITY OKANYE Ialkalinity
Isisombululo sesampuli: 4.0 g kwi-20 mL yamanzi angenayo i-carbon dioxide
Uhlalutyo: Yongeza i-0.1 mL ye-bromothymol blue TS.Ukuba isisombululo sityheli, i-titrate nge-0.01 N sodium hydroxide ukuvelisa umbala ozuba.Ukuba isisombululo siluhlaza okwesibhakabhaka, i-titrate nge-0.01 N hydrochloride acid ukuvelisa umbala ophuzi.
Indlela yokwamkela: I-NMT 0.2 mL ye-0.01 N sodium hydroxide okanye i-NMT 0.2 mL ye-0.01 N i-hydrochloric acid iyafuneka.
• UKULAHLEKO EKOMISENI <731>: Yomisa isampuli kwi-105° kangange-3 h: ilahlekelwa yi-NMT 1.0% yobunzima bayo.
IIMFUNO EZONGEZELELWEYO
Ukupakishwa NOKUGCINA: Yigcine kwisingxobo esivaleke kakuhle, kwaye ukhusele ekukhanyeni.Gcina kwiqondo lokushisa.
IMIGANGATHO YE-USP REFERENCE <11>
USP Acesulfame Potassium RS
Ukuthenga njani?Nceda uqhagamshelaneDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
Amava Eminyaka Eli-15?Sineminyaka engaphezu kwe-15 yamava ekwenziweni nasekuthumeleni kumazwe angaphandle uluhlu olubanzi oluphezulu lwamayeza aphakathi okanye amachiza alungileyo.
Iimarike eziphambili?Thengisa kwimarike yasekhaya, eMntla Melika, eYurophu, eIndiya, eKorea, eJapan, eOstreliya, njl.
Iingenelo?Umgangatho ophezulu, ixabiso elifikelelekayo, iinkonzo zengcali kunye nenkxaso yobugcisa, ukuhanjiswa ngokukhawuleza.
UmgangathoIsiqinisekiso?Inkqubo yokulawula umgangatho ongqongqo.Izixhobo zobuchwephesha zokuhlalutya ziquka i-NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, njl.
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Factory Audit?Uphicotho-zincwadi lwasefektri wamkelekile.Nceda wenze idinga kwangaphambili.
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Iikhowudi zoMngcipheko 36/37/38 - Ukucaphukisa amehlo, inkqubo yokuphefumula kunye nesikhumba.
Inkcazelo yoKhuseleko
S26 - Xa udibana namehlo, hlambulula ngokukhawuleza ngamanzi amaninzi kwaye ufune iingcebiso zonyango.
S36/37/39 - Nxiba iimpahla ezifanelekileyo zokukhusela, iiglavu kunye nokukhusela amehlo / ubuso.
WGK eJamani 1
RTECS RP4489165
Ikhowudi yeHS 2934990002
Ubuthi be-LD50 kwiigundane (mg / kg): 7431 ngomlomo, i-2243 ip (Mayer, Kemper)
Ngo-1976, i-Acesulfame-K yaqala ukwenziwa
Ngowe-1983, i-EU yavuma ukusetyenziswa kwayo ekutyeni nakwisiselo
Ngo-1988, i-FDA yavuma ukusetyenziswa kwayo kwi-ejenti yobumnandi betafile, itshungama kunye nekofu
Ngo-1992, i-China yavuma ukusetyenziswa kwayo ekutyeni nakwisiselo
Ngo-1994, i-FDA yavuma ukusetyenziswa kwayo kwisiraphu, ivenkile yokubhaka kunye neemveliso zobisi
Ngo-1995, i-FDA yavuma ukusetyenziswa kwayo kwisiselo esinxilisayo
Ngo-1998, i-FDA yavuma ukusetyenziswa kwayo kwiziselo ezithambileyo
Ngowama-2000, iJapan yavuma ukusetyenziswa kwayo
I-Acesulfame K (i-Acesulfame Potassium) (i-CAS: 55589-62-3) i-sweetener eyenziweyo.
Njengezimuncumuncu ezingenazo izondlo, akukho tshintsho kugxininiso lokutya kunye neziselo ezisetyenziswa kuluhlu lwe-pH ngokubanzi.
Usetyenziso oluqhelekileyo lwe-Acesulfame-K kukusetyenziswa kwetafile, iintsini zokuhlafuna, iziselo, ukutya, iimveliso zokubhaka, i-confectionary, iimveliso zococeko lomlomo, kunye namayeza.
Sweeteners.Emva kokungeniswa komzimba womntu awufuni, awuvelisi ukushisa, okufanelekileyo ukusetyenziswa kwizigulane ezinesifo sikashukela kunye nokukhuluphala.Ingasetyenziswa yodwa okanye idityaniswe nezinye izimuncumuncu.IAcesulfame K ihlala idityaniswa nezinye izimuncumuncu (idla ngokuba yiSucralose okanye iAspartame).Le mixube ichazwa njengokunika incasa efana ne-sucrose apho iswiti ngasinye sigquma incasa yomnye, kunye/okanye ibonise impembelelo ye-synergistic apho umxube ubaswiti kuneenxalenye zawo.
Ngokungafaniyo ne-Aspartame, i-Acesulfame K izinzile phantsi kobushushu, naphantsi kweemeko ze-acidic ephakathi okanye ezisisiseko, ezivumela ukuba isetyenziswe njengesongezo sokutya ekubhakeni, okanye kwiimveliso ezifuna ixesha elide leshelufu.Kwiziselo ze-carbonated, isoloko isetyenziswa ngokubambisana nenye i-sweetener, njenge-Aspartame okanye i-Sucralose.Ikwasetyenziswa njenge-sweetener kwi-protein shakes kunye neemveliso zamachiza, ngokukodwa amayeza ahlafunwayo kunye namanzi, apho anokwenza izithako ezisebenzayo zibe mnandi ngakumbi.
I-Acesulfame potassium isetyenziswa njenge-ejenti enencasa enzulu kwizinto zokuthambisa, ukutya, iimveliso zesiselo, ii-sweeteners eziphezu kwetafile, iivithamin kunye namalungiselelo amayeza, kubandakanya imixube yomgubo, iipilisi, kunye neemveliso ezingamanzi.Isetyenziswa kakhulu endaweni yeswekile kwimixube edityanisiweyo, kwaye njengentlama yokuthambisa yamazinyo.Amandla aqikelelweyo eswiti ngama-180-200 amaxesha e-sucrose, afana ne-aspartame, malunga nesinye kwisithathu esiswiti njenge-sucralose, isiqingatha esimnandi njenge-sodium saccharin, kunye namaxesha angama-4-5 amnandi kune-sodium cyclamate. kwaye ingasetyenziselwa ukugquma ezinye iimpawu zencasa ezingemnandanga.
I-Acesulfame Potassium isetyenziswa kakhulu kwiziselo, kwizinto zokuthambisa, ekutyeni, nakwimixube yamayeza, kwaye ngokuqhelekileyo ithathwa njengezinto ezingenatyhefu nezingakhuseliyo.Ucwaningo lwe-Pharmacokinetic lubonise ukuba i-acesulfame potassium ayinayo i-metabolized kwaye ikhutshwe ngokukhawuleza ingatshintshi kumchamo.Uphononongo lwexesha elide lokutyisa kwiimpuku kunye nezinja alubonisi bungqina bokuba i-acesulfame potassium i-mutagenic okanye i-carcinogenic.
I-WHO imisele ukuthathwa kwemihla ngemihla eyamkelekileyo ye-acesulfame potassium ukuya kuthi ga kwi-15 mg / kg ubunzima bomzimba.I-Scientific Committee for Foods of the European Union imisele ixabiso lemihla ngemihla lokuya kwi-9 mg / kg yesisindo somzimba.
I-LD50 (impuku, IP): 2.2 g/kg
I-LD50 (impuku, ngomlomo): 6.9-8.0 g / kg
IAcesulfame Potassium inozinzo oluhle.Kwifomu yobuninzi ayibonakalisi uphawu lokubola kwiqondo lokushisa eliphakathi kwiminyaka emininzi.Akukho kuncipha koswiti kubonwe kwisithuba esimalunga neminyaka emi-2.Uzinzo kumaqondo obushushu aphezulu kulungile, nangona okunye ukubola kuye kwaphawulwa emva kokugcinwa kwi-408℃ kangangeenyanga ezininzi.Ukwenziwa inzala kunye ne-pasteurization ayichaphazeli incasa ye-acesulfame potassium.
Izinto ezininzi kufuneka zigcinwe kwisitya esivaliweyo kwindawo epholileyo, eyomileyo kwaye ikhuselwe ekukhanyeni.
Ibandakanywe kwi-FDA ye-Inactive Ingredients Database yokulungiswa komlomo kunye neelwimi ezingaphantsi.Ibandakanyiwe kuLuhlu lwaseKhanada lweZithako ezaMkelweyo ezingezizo amayeza.Yamkelwe ukusetyenziswa eYurophu njengesongezo sokutya.Ikwamkelwe ukusetyenziswa kwiimveliso ezithile zokutya e-USA nakumazwe aliqela kuMbindi noMzantsi Melika, kuMbindi Mpuma, eAfrika, eAsia, naseOstreliya.
