I-Acyclovir CAS 59277-89-3 API Factory Antiviral High Quality
Ubonelelo lwabavelisi ngoBusulungekileyo obuPhezulu kunye noMgangatho oZinzileyo
Igama leMchiza: Acyclovir
CAS: 59277-89-3
I-Antiviral esetyenziselwa ukunyanga i-HSV kunye ne-VZV Infections
Umgangatho ophezulu we-API, iMveliso yoRhwebo
| Igama leMchiza | I-Acyclovir |
| Izithethantonye | iACV;iAcycloguanosine;9- [(2-Hydroxyethoxy)methyl]guanine;Aiclovir |
| Inombolo yeCAS | 59277-89-3 |
| Inombolo yeCAT | RF-API83 |
| Ubume beStokhwe | Kwi-Stock, iMveliso yeMveliso ukuya kumakhulu eeKilogram |
| Ifomula yeemolekyuli | I-C8H11N5O3 |
| Ubunzima beMolekyuli | 225.2 |
| Indawo yokunyibilika | 256.0 ~ 257.0℃ |
| Uphawu | Ruifu Chemical |
| Into | Iinkcukacha |
| Imbonakalo | Umgubo weCrystalline oMhlophe okanye ophantse wamhlophe |
| Ukuchongwa | Ukufunxwa kwe-infrared;Ixesha lokugcinwa (HPLC) |
| Izinto ezinxulumeneyo | |
| I-Acetylguanine+Diacetylguanine | ≤0.60% |
| Okunye Ukungacoceki Okukodwa okuphezulu | ≤0.20% |
| Ukungcola ngokupheleleyo | ≤1.0% |
| Isiqulatho samanzi (nge-KF) | ≤6.0% |
| Intsalela yezinyibilikisi (GC) | ≤500ppm |
| Umda weGuanine (HPLC) | ≤0.70% |
| Isivavanyi | 98.0% ~ 101.0% (C8H11N5O3 Kubalwa kwisiseko se-anhydrous) |
| Iintsimbi ezinzima | ≤20ppm |
| Umgangatho woVavanyo | Umgangatho woShishino |
| Ukusetyenziswa | I-Antiviral esetyenziselwa ukunyanga i-HSV kunye ne-VZV Infections |
Iphakheji: Ibhotile, ingxowa yefoyile yeAluminiyam, igubu lekhadibhodi, 25kg/Igubu, okanye ngokwemfuno yomthengi.
Imeko yoGcino:Gcina kwizikhongozeli ezivaliweyo kwindawo epholileyo neyomileyo;Khusela ekukhanyeni, ukufuma kunye nokuhlaselwa zizinambuzane.
I-Acyclovir (ACV, CAS 59277-89-3), eyaziwa ngokuba yi-Acycloguanosine, iyeza le-antiviral.Ngokuyintloko isetyenziselwa unyango lwe-herpes simplex usulelo, irhashalala, kunye neeshingles.Olunye usetyenziso lubandakanya uthintelo losulelo lwe-cytomegalovirus emva kokutshintshwa kunye neengxaki ezinzima zosulelo lwe-Epstein-Barr.Inokuthi ithathwe ngomlomo, isetyenziswe njengekhilimu, okanye ifakwe.I-Acyclovir isetyenziselwa ukunyanga izifo ze-HSV kunye ne-VZV.I-Acyclovir yi-analogue ye-purine yokwenziwa ephuma kwi-guanine.Isebenzisa imiphumo yayo kwi-herpes simplex virus (HSV) kunye ne-varicella-zoster virus ngokuphazamisa i-DNA synthesis ngokusebenzisa i-phosphorylation nge-viral thymidine kinase kunye nokuvinjelwa okulandelayo kwe-viral DNA polymerase, ngaloo ndlela inqanda ukuphindaphinda kwentsholongwane.I-Acyclovir yayinelungelo elilodwa lomenzi wechiza ngo-1974, kwaye yamkelwa ukuba isetyenziswe kwezonyango ngo-1981. Ikuluhlu loMbutho wezeMpilo weHlabathi wamaYeza ayimfuneko.Iyafumaneka njengeyeza elenziwe lafana nalawo aveliswe ngabenzi kwaye ithengiswa phantsi kwamagama eebhrendi ezininzi kwihlabathi jikelele.
