S-Adenosyl-L-Methionine (Ademetionine; SAMe) CAS 29908-03-0
I-Ruifu Chemical ngumenzi ohamba phambili we-S-Adenosyl-L-Methionine (i-Ademetionine; i-SAMe) (i-CAS: 29908-03-0) enomgangatho ophezulu.I-Ruifu Chemical inokubonelela ngenkonzo yehlabathi jikelele, ixabiso elikhuphisanayo, inkonzo egqwesileyo, encinci kunye nezixa ezininzi ezikhoyo.Thenga i-S-Adenosyl-L-Methionine,Please contact: alvin@ruifuchem.com
| Igama leMchiza | S-Adenosyl-L-Methionine |
| Izithethantonye | Ademetionine;S-Adenosylmethionine;SAM;SAM;AdoMet |
| Ubume beStokhwe | Kwi-Stock, iMveliso yoRhwebo |
| Inombolo yeCAS | 29908-03-0 |
| Ifomula yeemolekyuli | I-C15H22N6O5S |
| Ubunzima beMolekyuli | 398.44 g/mol |
| Indawo yokunyibilika | 267.0~269.0℃ |
| Inovakalelo | I-Hygroscopic kakhulu |
| Ukunyibilika kwamanzi | Inyibilika emanzini |
| Ivumba kunye neNcasa | Iimpawu |
| I-COA kunye ne-MSDS | Iyafumaneka |
| Isampulu | Iyafumaneka |
| Imvelaphi | Shanghai, China |
| Uphawu | Ruifu Chemical |
| Izinto | Iinkcukacha | Iziphumo |
| Imbonakalo | Phantse uMhlophe oFine Powder (Hygroscopic kakhulu) | Iqinisekisiwe |
| Ukunyibilika | Inyibilika emanzini | |
| Ukuchongwa | 1. Ukusabela kweekhemikhali | Ukusabela okulungileyo |
| 2. I-IR: Ihambelana ne-spectrum efunyenwe nge-RS | Iqinisekisiwe | |
| 3. Ixesha lokugcinwa kwencopho enkulu lihlangabezana nezicelo | Iqinisekisiwe | |
| Ixabiso le-Acid | 1.5~2.5 | 1.9 |
| Ukucaca kunye nombala wesisombululo | AyinaMbala Ngokugqithisileyo kune-RS Y1 | Iqinisekisiwe |
| Amanzi nguKarl Fischer | ≤3.00% | 2.2% |
| Intsalela kwi-Ignition | ≤0.30% | 0.14% |
| Iintsimbi ezinzima (Pb) | ≤10ppm | <10ppm |
| Endotoxin | ≤0.3EU/mg | Iqinisekisiwe |
| IMicrobiological | Ufanele Uyifezekise Imfuneko | |
| Ukubalwa kwePleti iyonke | ≤1000cfu/g | 55cfu/g |
| Igwele kunye noMngundo | ≤100cfu/g | 12cfu/g |
| E. Coli | Ukungabikho/10g | Iyahambelana |
| S. Aureus | Ukungabikho/10g | Iyahambelana |
| Salmonella | Ukungabikho/10g | Iyahambelana |
| S-Adenosyl-L-Homocysteine | ≤0.50% | 0.10% |
| Methioadenosine | ≤1.00% | 0.24% |
| Adenine | ≤0.50% | 0.09% |
| Izinto ezinxulumeneyo | ||
| Olunye Ukungcola Okukhulu | ≤0.20% | 0.01% |
| Olunye Ukungcola Kuphelele | ≤0.50% | 0.006% |
| (S,S) Isomer | >62.0% | 79.4% |
| I-Butanedisulfonate | 46.0 ~ 49.0% (Isekwe Komisiweyo) | 47.5% |
| Ademetionine | 50.0 ~ 53.0% (Base on Dried) | 52.1% |
| Isiqulatho esipheleleyo | >97.5% (Isekwe Komisiweyo) | 99.6% |
| Ukuqukumbela | Imveliso ivavanyiwe kwaye ihambelana neenkcukacha ezinikiweyo | |
| Beka ubomi kwishelufa | Iminyaka emi-2 xa igcinwe ngokufanelekileyo | |
Umqulu:Ibhotile, ingxowa yefoyile yeAluminiyam, 25kg/Igubu lekhadibhodi, okanye ngokwemfuno yomthengi.
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Ukuthenga njani?Nceda uqhagamshelaneDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
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Iikhowudi zoMngcipheko R49 - Inokubangela umhlaza ngokuphefumla
I-R23 - Inetyhefu ngokuphefumla
I-R34 - Ibangela ukutsha
INkcazelo yoKhuseleko S53-Kuphephe ukuba sesichengeni-fumana imiyalelo eyodwa phambi kokusetyenziswa.
S23 - Musa ukuphefumla umphunga.
S36/37/39 - Nxiba iimpahla ezifanelekileyo zokukhusela, iiglavu kunye nokukhusela amehlo / ubuso.
S45 - Kwimeko yengozi okanye ukuba uziva ungaphilanga, funa ingcebiso kagqirha ngokukhawuleza (bonisa ileyibhile nanini na kunokwenzeka.)
Ikhowudi yeHS 2934999099
I-S-Adenosyl-L-Methionine (i-Ademetionine; i-SAMe) (i-CAS: i-29908-03-0) i-cosubstrate eqhelekileyo ebandakanyekayo ekudlulisweni kweqela le-methyl.I-SAMe yafunyanwa okokuqala e-Itali ngu-GL Cantoni ngo-1952, i-SAMe yimolekyuli eveliswa rhoqo zizo zonke iiseli eziphilayo, inokuthintela umhlaza wesibindi, ukukhuthaza ukwakhiwa kwezicubu ze-cartilaginous kunye ne-concrescence, inokunceda ukulwa nokudakumba, isifo se-Alzheimer, isifo sesibindi, kunye neentlungu I-osteoarthritis, i-SAMe ngoku yamkelwe kwihlabathi jikelele njengeyeza elibalulekileyo lokunyanga izifo zesibindi.Namhlanje i-SAMe iqhele ukusetyenziswa kumayeza, kukhathalelo lwempilo kwishishini lokutya kwintengiso yasekhaya neyamanye amazwe.I-SAMe ithengiswa eMelika njengesongezelelo sokutya.
1. I-S-Adenosyl-L-Methionine iyisondlo esilungileyo sesibindi, esinokuthintela utywala, iziyobisi kunye nomonakalo weseli yesibindi;
2. I-S-Adenosyl-L-Methionine inempembelelo ebalulekileyo yokukhusela kwi-hepatitis esebenzayo engapheliyo kunye nezinye izinto ezibangela umonakalo wesibindi, isifo senhliziyo, umhlaza njalo njalo.
3. I-S-Adenosyl-L-Methionine ifunyenwe iyasebenza njengamachiza okunyanga isifo samathambo kunye nokudakumba okukhulu.
4. E-United States, i-SAM ithengiswa njengesongezelelo sesondlo phantsi kwegama lentengiso elithi SAM-e (iphinde ibhalwe SAME okanye SAMe).Ezinye izifundo zibonise ukuba ukuthatha i-SAM rhoqo kunokunceda ukulwa nokudakumba, isifo sesibindi, kunye neentlungu ze-osteoarthritis.Inani lolingo lwezonyango lubonise ukuba lulungile kuxinzelelo, izifo ezithile zesibindi kunye ne-osteoarthritis.Zonke ezinye iimpawu azikaqinisekiswa.
5. Ngokweklinikhi esetyenziselwa ukuphucula umsebenzi wesibindi.Ukudibanisa ne-L-DOPA kunyango lwe-Parkinson's disease kunokuphucula ukusebenza kwe-L-dopa kunye nokunciphisa iziphumo ebezingalindelekanga.Intlungu yendawo, ukuxhalaba okwethutyana kunye nokungalali kwindawo yokutofa kunokubonwa.
I-S-Adenosyl-L-Methionine (i-Ademetionine; i-SAMe) (i-CAS: i-29908-03-0) nayo inefuthe elihle lonyango kwi-arthritis, i-fibrous muscle, i-migraine kunye nezinye izifo, kwaye inempembelelo encinci.Kwangoo-1970s, i-SAMe yayisetyenziswa njengechiza elimiselweyo kwi-arthritis eYurophu.Ngo-1999, i-US FDA yavuma i-SAMe njengemveliso yezempilo kwaye iye yaba yenye yeemveliso zesondlo ezithengiswa kakhulu e-United States.
I-S-Adenosyl-L-Methionine ilungiswa ngokuyintloko nge-chemical synthesis, i-fermentation kunye nokuguqulwa kwe-enzymatic.Indlela yokuvutshelwa kukongeza i-precursor L-Methionine kwindawo esisiseko equlethe imithombo ye-C kunye ne-N, kunye nenani elikhulu le-S-Adenosylmethionine linokufumaneka ngokuhlakulela iiseli ze-microbial.Le ngoku yeyona ndlela iphambili yemveliso yemizi-mveliso ye-S-Adenosylmethionine.Phakathi kwazo, ii-microorganisms ezisetyenziselwa ukuvutshelwa zingafumaneka ngokuhlola okanye ukudibanisa iindlela zokwakha, ezibhalwe kumanqaku amaninzi kunye namalungelo obunikazi ekhaya nakwamanye amazwe.Ezinye izifundo zibonelele ngendlela yokulungiselela i-S-adenosylmethionine, usebenzisa i-polyhydroxy reagents ephilayo ukukhusela umsebenzi we-enzyme, usebenzisa i-adenosine triphosphate precursor, i-L-Methionine kunye ne-phosphate ions njenge-substrates, i-glucose okanye / kunye ne-maltose njengabanikezeli bamandla, ukongeza ukubunjwa. yeeyoni zetsimbi, kunye nokusetyenziswa koxinzelelo lwemveliso oluvuzayo ukwenza ukuveliswa kwe-S-Adenosylmethionine kwiiseli ezipheleleyo.Ukusebenzisa ukubunjwa kwee-ion zetsimbi ukulawula ukuhamba kwe-metabolic ukuphucula amandla okuzidibanisa ngokufanelekileyo, ukongeza ii-reagents ze-organic ukukhusela umsebenzi webhaktheriya kunye ne-enzymes, usebenzisa i-permeable strain yemveliso ukulungiselela i-S-Adenosylmethionine, ukunciphisa ixesha lokudibanisa, kunye yenza imveliso iqokelele ngaphandle kweseli, enokugcina iindleko zokwahlula okulandelayo kunye nokwenza lula amanyathelo okusebenza.
Ulwazi malunga nokhuseleko lwexesha elide lwe-S-Adenosyl-L-Methionine lulinganiselwe kuba abathathi-nxaxheba kwizifundo ezininzi bathathe ixesha elifutshane kuphela.Nangona kunjalo, kwisifundo esinye sesifo sesibindi esinxulumene notywala, abathathi-nxaxheba bathatha i-S-Adenosyl-L-methionine iminyaka eyi-2;kweso sifundo, akukho miphumo emibi echazwe.
Abantu abane-bipolar disorder (isigulo esiphawulwa kukuguquka kwemizwelo, ukusuka kuxinzelelo ukuya kwi-mania) akufuneki bathathe i-SAMe ngeempawu zabo ezidakumbisayo ngaphandle kokuba phantsi kweliso lomboneleli wezempilo kuba i-SAMe inokuzenza mbi ngakumbi iimpawu ze-mania.
Nangona i-S-Adenosyl-L-Methionine isetyenziselwa ukuphatha i-cholestasis ngexesha lokukhulelwa, ukhuseleko lwayo ngexesha lokukhulelwa aluzange lusekwe.
I-SAMe inokunciphisa iziphumo ze-levodopa (L-dopa), ichiza elisetyenziselwa ukunyanga isifo sikaParkinson.Kwakhona kunokwenzeka ukuba i-SAMe inokunxibelelana namachiza kunye nezongezelelo zokutya ezinyusa amanqanaba e-serotonin (ikhemikhali eveliswa ngamaseli e-nerve), njenge-antidepressants, i-L-tryptophan, kunye ne-St.
Kukho inkxalabo yethiyori malunga nokusetyenziswa kwe-SAMe ngabantu abangenamajoni omzimba (njengabo bane-HIV).Abantu abane-Immunocompromised basemngciphekweni wosulelo lwe-Pneumocystis carinii, kwaye i-SAMe iphucula ukukhula kwale microorganism.
Iziphumo ebezingalindelekanga ze-SAMe aziqhelekanga, kwaye xa zithe zenzeka zikholisa ukuba ziingxaki ezincinci ezifana nesicaphucaphu okanye ukuphazamiseka kokutya.
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