Afatinib Dimaleate Intermediate CAS 314771-88-5 Ubunyulu > 99.0% (HPLC) Factory
I-Ruifu Chemical Supply Intermediates ye-Afatinib
Afatinib CAS 439081-18-2
Afatinib Dimaleate CAS 850140-73-7
(S)-(+)-3-Hydroxytetrahydrofuran CAS 86087-23-2
(Dimethylamino)i-acetaldehyde I-Diethyl Acetal CAS 3616-56-6
trans-4-Dimethylaminocrotonic Acid Hydrochloride CAS 848133-35-7
I-Diethylphosphonoacetic Acid CAS 3095-95-2
7-Fluoro-6-Nitroquinazolin-4 (1H)-enye CAS 162012-69-3
I-7-Chloro-6-Nitro-4-Hydroxyquinazoline CAS 53449-14-2
N-(3-Chloro-4-Fluorophenyl)-7-Fluoro-6-Nitroquinazolin-4-Amine CAS 162012-67-1
(S)-N4-(3-Chloro-4-Fluorophenyl)-7-((Tetrahydrofuran-3-yl)oxy)quinazoline-4,6-DiamineI-CAS 314771-76-1
(S)-N-(3-Chloro-4-Fluorophenyl)-6-Nitro-7-((Tetrahydrofuran-3-yl)oxy)quinazolin-4-AmineI-CAS 314771-88-5
Igama leMchiza | (S)-N-(3-Chloro-4-Fluorophenyl)-6-Nitro-7-((Tetrahydrofuran-3-yl)oxy)quinazolin-4-Amine |
Izithethantonye | N-(3-Chloro-4-Fluorophenyl)-6-Nitro-7-[(3S)-oxolan-3-yl]oxyquinazolin-4-Amine;7-((S)-Tetrahydrofuran-3-yloxy)-4-(3-Chloro-4-Fluorophenyl)amino-6-Nitroquinazoline;Afatinib Ukungcola |
Inombolo yeCAS | 314771-88-5 |
Inombolo yeCAT | RF-PI2027 |
Ubume beStokhwe | Kwi-Stock, iMveliso yoMveliso ukuya kwiiToni |
Ifomula yeemolekyuli | I-C18H14ClFN4O4 |
Ubunzima beMolekyuli | 404.78 |
Ukuxinana | 1.534±0.060 g/cm3 |
Uphawu | Ruifu Chemical |
Into | Iinkcukacha |
Imbonakalo | Umgubo oMthubi ukuya kokuKhanya |
Ubunyulu / Indlela yokuHlalutya | >99.0% (HPLC) |
Ilahleko ekomisweni | <0.50% |
Ukungacoceki komntu | <0.50% |
Ukungcola ngokupheleleyo | <1.00% |
Iintsimbi ezinzima | ≤20ppm |
Umgangatho woVavanyo | Umgangatho woShishino |
Ukusetyenziswa | Phakathi kwe-Afatinib Dimaleate (CAS: 850140-73-7) |
Iphakheji: Ibhotile, ingxowa yefoyile yeAluminiyam, 25kg/Igubu lekhadibhodi, okanye ngokwemfuno yomthengi
Imeko yoGcino:Gcina kwizikhongozeli ezivaliweyo kwindawo epholileyo neyomileyo;Khusela ukukhanya kunye nokufuma
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(S)-N-(3-Chloro-4-Fluorophenyl)-6-Nitro-7-((Tetrahydrofuran-3-yl)oxy)quinazolin-4-Amine (CAS: 314771-88-5) isetyenziswa kwi ukulungiswa kwe-Afatinib Dimaleate (CAS: 850140-73-7).I-Afatinib lichiza ekujoliswe kulo elichasene nomhlaza, isizukulwana esitsha sechiza ekujoliswe kulo ngomlomo, iyeza lokuqala lehlabathi elichasene nomhlaza elibophelela ngokungenakuguquleka kusapho lwe-ErbB, kwaye lisebenza ngakumbi kwaye lijolise kwiiBlocks uphawu olubangela ukukhula kweeseli zomhlaza. , ukunciphisa okanye ukulibazisa ukwanda kweeseli zomhlaza.I-Afatinib yeyeklasi yamachiza eyaziwa ngokuba yi-tyrosine kinase inhibitors.Isebenza ngokuthintela umsebenzi weeprotheni ezimbini ezinxulumene ngokusondeleyo, i-epidermal growth factor receptor (EGFR) kunye ne-epidermal growth factor receptor 2 (HER2).Isetyenziselwa unyango lodidi lokuqala lwezigulane ezinomhlaza wemiphunga we-metastatic ongeyonxalenye encinci.I-Afatinib lichiza ekujoliswe kulo elichasene nomhlaza, isizukulwana esitsha sechiza ekujoliswe kulo ngomlomo, iyeza lokuqala lehlabathi elichasene nomhlaza elibophelela ngokungenakuguquleka kusapho lwe-ErbB, kwaye lisebenza ngakumbi kwaye lijolise kwiiBlocks uphawu olubangela ukukhula kweeseli zomhlaza. , ukunciphisa okanye ukulibazisa ukwanda kweeseli zomhlaza.
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(Dimethylamino)acetaldehyde Diethyl Acetal CAS ...
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(S)-(+)-3-Hydroxytetrahydrofuran CAS 86087-23-2...
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I-Diethylphosphonoacetic Acid CAS 3095-95-2 Purit...
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Trans-4-Dimethylaminocrotonic Acid Hydrochlorid...
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Afatinib Dimaleate Intermediate CAS 314771-76-1...
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Afatinib Dimaleate Intermediate CAS 314771-88-5...
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N-(3-Chloro-4-Fluorophenyl)-7-Fluoro-6-Nitroqui...
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I-7-Chloro-6-Nitro-4-Hydroxyquinazoline CAS 53449...
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7-Fluoro-6-Nitroquinazolin-4 (1H)-enye CAS 162012...
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I-Afatinib CAS 439081-18-2 Ubunyulu > 99.5% (HPLC) F...
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Afatinib Dimaleate CAS 850140-73-7 Ubunyulu > 99.5...