Anastrozole CAS 120511-73-1 API Factory High Quality Featured Image

I-Anastrozole CAS 120511-73-1 API Factory High Quality

Inkcazelo emfutshane:

Igama: Anastrozole

CAS: 120511-73-1

Imbonakalo: Mhlophe ukuya kuMhlophe-Mhlophe wePowder

Uvavanyo: 98.0% ~ 102.0%

AnastrozoleUnyango loMhlaza wamabele

Umgangatho ophezulu we-API, iMveliso yoRhwebo

Inquiry: alvin@ruifuchem.com

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Iinkcukacha zeMveliso

Iimveliso ezinxulumeneyo

Iithegi zeMveliso

Inkcazo:

Ubonelelo lwabavelisi ngoBusulungekileyo obuPhezulu kunye noMgangatho oZinzileyo
Igama leKhemikhali: Anastrozole
CAS: 120511-73-1

Iipropati zeMichiza:

Igama	Anastrozole
Izithethantonye	I-Arimidex;α,α,α',α'-Tetramethyl-5-(1H-1,2,4-triazol-1-ylmethyl)-1,3-benzenediacetonitrile
Inombolo yeCAS	120511-73-1
Inombolo yeCAT	RF-API74
Ubume beStokhwe	Kwi-Stock, iMveliso yeMveliso ukuya kumakhulu eeKilogram
Ifomula yeemolekyuli	C17H19N5
Ubunzima beMolekyuli	293.37
Ukunyibilika	Inyibilika kwi-DMSO kunye ne-Ethanol
Uphawu	Ruifu Chemical

Iinkcukacha:

Into	Iinkcukacha
Imbonakalo	Mhlophe ukuya kuMhlophe oMhlophe wePowder
Isazisi A	I-IR/MS Iyahambelana nomgangatho wereferensi
Isazisi B	I-HPLC kunye nepeak shape: Ihambelana nereferensi
Indawo yokunyibilika	81.0~84.0℃
Isiqulatho samanzi (nge-KF)	≤0.30%
Intsalela kwi-Ignition	≤0.10%
Ilahleko ekomisweni	≤0.50%
Iintsimbi ezinzima	≤10ppm
Izinto ezinxulumeneyo
Ukungcola A	≤0.10%
Ukungcola B	≤0.20%
Ukungcola C	≤0.20%
Ukungcola D	≤0.10%
Ukungcola E	≤0.10%
Ukungacoceki Okunye	≤0.10%
Ukungcola ngokupheleleyo	≤0.50%
Izinyibilikisi ezishiyekileyo
Cyclohexane	≤0.30%
I-Ethyl Acetate	≤0.50%
Isivavanyi	98.0% ~ 102.0% (kwisiseko esomileyo)
Beka ubomi kwishelufa	Iinyanga ezingama-24
Umgangatho woVavanyo	uMgangatho woShishino;Umgangatho we-United States Pharmacopoeia (USP).
Ukusetyenziswa	Unyango loMhlaza wamabele

Ukupakishwa kunye noGcino:

Iphakheji: Ibhotile, ingxowa yefoyile yeAluminiyam, igubu lekhadibhodi, 25kg/Igubu, okanye ngokwemfuno yomthengi.

Imeko yoGcino:Gcina kwizikhongozeli ezivaliweyo kwindawo epholileyo neyomileyo;Khusela ekukhanyeni, ukufuma kunye nokuhlaselwa zizinambuzane.

Izinto eziluncedo:

FAQ:

Isicelo:

I-Anastrozole (i-CAS 120511-73-1), i-non-steroidal, isizukulwana sesithathu se-achiral triazole derivative ithengiswa njenge-ARIMIDEX® yi-AstraZeneca Pharmaceuticals LP1.Ngomnye wesizukulwana sesithathu se-aromatase inhibitor ekhuphisana kakhulu kunye ne-inhibitor ekhethiweyo ye-aromatase, ngaloo ndlela ivimbela ukuguqulwa kwe-testosterone kwi-estradiol kunye ne-androstenedione kwi-estrone.Ukuvinjelwa kwe-enzayimu yearomatase kwenzeka ngokukodwa ngokubophelelana kwe-aromatase kwi-hemegroup ye-cytochrome P450, ukuncipha kwe-estrogen biosynthesis kwizicubu ezijikelezayo zomzimba kunye nasebeleni.

I-Anastrozole lunyango olunyanyezelwayo jikelele kumhlaza wamabele okwinqanaba lokuqala.Njengezinye i-aromatase inhibitors, eyona mpembelelo yayo ibaluleke kakhulu yayiyingozi eyongeziweyo yokuphuka kwamathambo, apho i-anastrozole yayikhawulelwe kwixesha lonyango.Ibonakala inetyhefu encinci xa ithelekiswa nechemotherapy;nangona kunjalo, kuye kwaqatshelwa ukuba izigulane ezininzi eziphathwe nge-anastrozole ziye zakhalaza ngeempawu ezidibeneyo kunokuba zilindelwe, ngokukodwa ukuqina kwedijithali kufana ne-rheumatoid arthritis.Olunye ulingo lwezonyango lwe-anastrozole lwabasetyhini abasemva kokuya exesheni abanomhlaza wamabele eYurophu nase-United States bachaze ukuphazamiseka kwe-musculoskeletal njengeziganeko ezimbi.I-Anastrozole (i-Arimidex®) yi-inhibitor ye-aromatase evunyiweyo kwi-EU, e-US nakwamanye amazwe emhlabeni jikelele ukuba isetyenziswe njengonyango lwe-adjuvant kubasetyhini be-postmenopausal kunye nesigaba sokuqala, umdlavuza webele we-hormone receptor-positive.Ikwavunyiwe kwi-EU nakwamanye amazwe kwihlabathi jikelele ngokuqhubeka nonyango lwe-adjuvant kwabasetyhini abasele beneminyaka eyi-2-3 ye-adjuvant tamoxifen yonyango lomhlaza wamabele.