Argatroban CAS 74863-84-6 API Factory High Purity Anticoagulant
Ubonelelo loMvelisi kwiArgatroban eNxulumeneyo naMaphakathi:
I-Ethyl (2R,4R)-4-Methyl-2-Piperidinecarboxylate CAS 74892-82-3
N-Nitro-1,2,3,4-tetradehydro Argatroban Ethyl Ester CAS 74874-09-2
I-3-Methyl-8-Quinolinesulphonyl Chloride CAS 74863-82-4
Argatroban Monohydrate CAS 141396-28-3
Argatroban Anhydrous CAS 74863-84-6
Igama leMchiza | Argatroban |
Izithethantonye | Argatroban Anhydrous |
Inombolo yeCAS | 74863-84-6 |
Inombolo yeCAT | RF-API67 |
Ubume beStokhwe | Kwi-Stock, iMveliso yeMveliso ukuya kumakhulu eeKilogram |
Ifomula yeemolekyuli | I-C23H36N6O5S |
Ubunzima beMolekyuli | 508.63 |
Indawo yokunyibilika | 188.0 ~ 189.0℃ |
Indawo yokubilisa | 801.3ºC ku-760 mmHg |
Ukuxinana | 1.47 g/cm3 |
Imeko yokuthumela ngenqanawa | Ithunyelwe Ngaphantsi Kweqondo Lobushushu Le-Ambient |
Uphawu | Ruifu Chemical |
Into | Iinkcukacha |
Imbonakalo | Mhlophe ukuya kuMhlophe oMhlophe wePowder |
Ukuchongwa kwe-HPLC | Ixesha lokugcinwa kwencopho yomgaqo efunyenwe kwisisombululo soVavanyo sihambelana neso sifunyenwe kwisisombululo esiPhakathi, njengovavanyo kwi-Assay |
Ukuchongwa kwe-IR | Ingqinelana ne-IR Spectrum ye-AG RS |
Ukuchongwa kwe-UV | Kwi-259nm kunye ne-332nm wavelength indawo kufuneka ibe nokufunxa okuphezulu. |
Amanzi | 2.5-4.5% |
Umbala Wesisombululo & Ukucaca | Isisombululo kufuneka Sicace Imibala |
Nxulumanisa Izinto | |
Ukungacoceki A + Ukungacoceki H | ≤0.10% |
Ukungcola B | ≤0.10% |
Ukungcola C + Ukungacoceki E | ≤0.10% |
Ukungcola D | ≤0.10% |
Ukungcola I | ≤0.10% |
I-Bach yokungcola okungachazwanga | ≤0.10% |
Ukungcola ngokupheleleyo | ≤0.30% |
Izinyibilikisi ezishiyekileyo | |
IMethanol | ≤3000ppm |
I-Ethanol | ≤5000ppm |
Dichloromethane | ≤600ppm |
I-Ethyl Acetate | ≤5000ppm |
I-Enantiomer (HPLC) | ≤0.10% |
Umlinganiselo we-Isomer (HPLC) | 30.0%-40.0% |
I-Chloride | ≤0.01% |
Intsalela kwi-Ignition | ≤0.10% |
Iintsimbi ezinzima | ≤10ppm |
Iintsholongwane ze-Endotoxins | <5EU/mg |
Umda weMicrobial | TAMC ≤1000 cfu/g |
Isivavanyi | 98.0% -102.0% (kwisiseko se-anhydrous) |
Umgangatho woVavanyo | Umgangatho woShishino |
Ukusetyenziswa | API, Synthetic Antithrombotic Agent Anticoagulant |
Iphakheji: Ibhotile, ingxowa yefoyile yeAluminiyam, Igubu lekhadibhodi, 25kg/Igubu, okanye ngokwemfuno yomthengi.
Imeko yoGcino:Gcina kwizikhongozeli ezivaliweyo kwindawo epholileyo neyomileyo;Khusela ekukhanyeni, ukufuma kunye nokuhlaselwa zizinambuzane.
I-Shanghai Ruifu Chemical Co., Ltd. ngumenzi ohamba phambili kunye nomthengisi we-Argatroban (i-CAS: 74863-84-6) enomgangatho ophezulu, i-API.
I-Argatroban (i-CAS: 74863-84-6) yinto entsha ye-antithrombotic agent eluncedo ekugcinweni kwe-anticoagulation kubo ischemic stroke kunye nokusabalalisa i-intravascular coagulation.Yi-anticoagulant eyi-molecule encinci ye-thrombin inhibitor.Kwi-2000, i-argatroban ilayisensi yi-Food and Drug Administration (FDA) ye-prophylaxis okanye unyango lwe-thrombosis kwizigulane ezine-heparin-induced thrombocytopenia (HIT).Kwi-2002, yavunywa ukuba isetyenziswe ngexesha lokungenelela kwe-coronary percutaneous kwizigulane ezine-HIT okanye ezisengozini yokuphuhlisa.Kwi-2012, yavunywa yi-MHRA e-UK ye-anticoagulation kwizigulane ezine-heparin-induced thrombocytopenia Type II (HIT) ezifuna unyango lwe-antithrombotic parenteral.