I-Aripiprazole ePhakathi CAS 129722-34-5 Ubunyulu > 98.0% (HPLC)
AbaPhakathi boBonelelo boMvelisi be-Aripiprazole Ngobunyulu obuPhezulu
Aripiprazole API CAS 129722-12-9
1-(2,3-Dichlorophenyl)piperazine Hydrochloride CAS 119532-26-2
I-7-Hydroxy-3,4-Dihydro-2 (1H)-Quinolinone CAS 22246-18-0
7-(4-Bromobutoxy)-3,4-Dihydro-2(1H)-Quinolinone CAS 129722-34-5
| Igama leMchiza | 7-(4-Bromobutoxy)-3,4-Dihydro-2(1H)-Quinolinone |
| Izithethantonye | I-7-(4-Bromobutoxy) -3,4-Dihydroquinolin-2 (1H) -enye;I-7-(4-Bromobutoxy) -1,2,3,4-Tetrahydro-2-Oxoquinoline;3,4-Dihydro-7-(4-Bromobutoxy)-2(1H)-Quinolinone;Ukungacoceki kweAripiprazole 3 |
| Inombolo yeCAS | 129722-34-5 |
| Inombolo yeCAT | RF-PI2269 |
| Ubume beStokhwe | Kwi-Stock, iMveliso yoMveliso ukuya kwiiToni |
| Ifomula yeemolekyuli | I-C13H16BrNO2 |
| Ubunzima beMolekyuli | 298.18 |
| Ukuxinana | 1.383 g/cm3 |
| Uphawu | Ruifu Chemical |
| Into | Iinkcukacha |
| Imbonakalo | Umgubo weCrystal oMhlophe okanye oMthubi |
| Ubunyulu / Indlela yokuHlalutya | >98.0% (HPLC) |
| Indawo yokunyibilika | 110.0 ~ 114.0℃ |
| Ilahleko ekomisweni | <1.00% |
| Intsalela kwi-Ignition | <0.50% |
| Iintsimbi ezinzima (njenge Pb) | ≤20ppm |
| Proton NMR Spectrum | Iyahambelana neSakhiwo |
| Umgangatho woVavanyo | Umgangatho woShishino |
| Ukusetyenziswa | Umbindi we-Aripiprazole (CAS: 129722-12-9) |
Iphakheji: Ibhotile, ingxowa yefoyile yeAluminiyam, 25kg/Igubu lekhadibhodi, okanye ngokwemfuno yomthengi
Imeko yoGcino:Gcina kwizikhongozeli ezivaliweyo kwindawo epholileyo neyomileyo;Khusela ukukhanya kunye nokufuma
I-7-(4-Bromobutoxy) -3,4-Dihydro-2 (1H)-Quinolinone (CAS: 129722-34-5) iphakathi kwi-synthesis ye-Aripiprazole (CAS: 129722-12-9).Imveliso yokunciphisa kwiipilisi ze-Aripiprazole.Aripiprazole (Abilify).Elona litsha, i-longactingaripiprazole (i-arylpiperazine quinolinone derivative), ibonakala ngathi iyinxalenye ye-agonist ye-D2 receptors (okt, ivuselela ii-receptors ezithile ze-D2 ngelixa ivimba ezinye ngokuxhomekeke kwiindawo zazo zengqondo kunye noxinzelelo lwechiza).I-Bioavailability ye-Aripiprazole ijikeleze i-87%, kunye ne-peak concentration ye-plasma efunyenwe kwi-3 kwiiyure ze-5 emva kokuthatha.I-metabolized yi-dehydrogenation, i-oxidative hydroxylation, kunye ne-N-dealkylation, ngokuyininzi idibene ne-CYPs ye-hepatic 3A4 kunye ne-2D6.Kunyango lwe-schizophrenia kunye nokuphazamiseka kwengqondo okuhlobene.I-dopamine ekhethiweyo ye-D2-receptor antagonist kunye ne-dopamine autoreceptor agonist umsebenzi.I-Antipsychotic.
